Kirsten Grønbæk

Kirsten Grønbæk

Clinical Professor

Member of:

  • Internal Medicine: Haematology


  1. Published

    DNA Methyltransferase Inhibitors in Myeloid Cancer: Clonal Eradication or Clonal Differentiation?

    mxz703, mxz703 & Grønbæk, Kirsten, Sep 2017, In: Cancer journal (Sudbury, Mass.). 23, 5, p. 277-285 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  2. Published

    Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation

    mxz703, mxz703, Treppendahl, M. B., Skovbo, A., Holm, M. S., Friis, L. S., Hokland, M. & Grønbæk, Kirsten, 2015, In: OncoTarget. 6, 11, p. 9612-26 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    How a Medical Association Can Make a Difference in a Crisis Situation

    van Havre, N., Orsini, E., Almeida, A., Gribben, J., Bolanos, N., Doeswijk, R., Gaidano, G., Mouhssine, S., Doehner, K., Grønbæk, Kirsten, Porkka, K. & Macintyre, E., 2022, In: HemaSphere. 6, 9, 3 p., 765.

    Research output: Contribution to journalEditorialResearchpeer-review

  4. Published

    Risk of new malignancies among patients with CLL treated with chemotherapy: results of a Danish population-based study

    da Cunha-Bang, C., Rostgaard, K., Andersen, M. A., Rotbain, E. C., Grønbæk, Kirsten, Frederiksen, H., Niemann, Carsten & Hjalgrim, Henrik, 2021, In: British Journal of Haematology. 193, 2, p. 339-345

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Myelomonocytic Leukemia: Clinical and Molecular Genetic Prognostic Factors in a Nordic Population

    Wedge, E., Hansen, J. W., Dybedal, I., Creignou, M., Ejerblad, E., Lorenz, F., Werlenius, O., Ungerstedt, J., Holm, M. S., Nilsson, L., Kittang, A. O., Antunovic, P., Rohon, P., Andersen, M. K., Papaemmanuil, E., Bernard, E., Jädersten, M., Hellström-Lindberg, E., Grønbæk, K., Ljungman, P. & 1 others, Friis, L. S., 2021, In: Transplantation and Cellular Therapy. 27, 12, p. 991.e1-991.e9

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Improved Outcomes after Allogenic Hematopoietic Stem Cell Transplantation with Fludarabine/Treosulfan for Patients with Myelodysplastic Syndromes

    Wedge, E., Sengeløv, Henrik, Hansen, Jakob Werner, Andersen, N. S., Schjødt, I., Petersen, S. L., Kornblit, B., Grønbæk, Kirsten & Friis, L. S., 2020, In: Biology of Blood and Marrow Transplantation. 26, 6, p. 1091-1098

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Global hypomethylation is an independent prognostic factor in diffuse large B cell lymphoma

    Wedge, E., Hansen, Jakob Werner, Garde, C., Asmar, F., Tholstrup, Dorte Maegaard, Kristensen, S. S., Munch-Petersen, H. D., Ralfkiaer, E., Brown, Peter de Nully, Grønbæk, Kirsten & Kristensen, L. S., Jul 2017, In: American Journal of Hematology. 92, 7, p. 689-694 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Impact of U2AF1 mutations on circular RNA expression in myelodysplastic neoplasms

    Wedge, E., Ahmadov, U., Hansen, T. B., Gao, Z., Tulstrup, Morten Rytter, Côme, Christophe Roger Michel, Nonavinkere Srivatsan, S., Ahmed, T., Jespersen, Jakob Schmidt, Schlotmann, Balthasar Clemens, Schöllkopf, C., Raaschou-Jensen, K., Ødum, Niels, Kjems, J., Bak, R. O., Walter, M. J., Grønbæk, Kirsten & Kristensen, L. S., 2023, In: Leukemia. 37, p. 1113-1125

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Angiotensinogen promoter methylation predicts bevacizumab treatment response of patients with recurrent glioblastoma

    Urup, T., Gillberg, Linn, Kaastrup, K., Lü, M. J. S., Michaelsen, Signe Regner, Andrée Larsen, V., Christensen, I. J., Broholm, H., Lassen, Ulrik Niels, Grønbæk, Kirsten & Poulsen, H. S., 2020, In: Molecular Oncology. 14, 5, p. 964-973

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Angiotensinogen promoter methylation to predict bevacizumab response in recurrent glioblastoma patients

    Urup, T., Gillberg, Linn, Kaastrup, K., Lu, M. S., Michaelsen, Signe Regner, Larsen, V. A., Christensen, I. J., Broholm, H., Lassen, Ulrik Niels, Grønbæk, Kirsten & Poulsen, H. S., 2019, In: Neuro-Oncology. 21, Supplement 6, p. vi149

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  11. Published

    Twin DNA Methylation Profiling Reveals Flare-Dependent Interferon Signature and B Cell Promoter Hypermethylation in Systemic Lupus Erythematosus

    Ulff-Møller, C. J., Asmar, F., Liu, Y., Svendsen, A. J., Busato, F., Grønbæk, Kirsten, Tost, J. & Jacobsen, Søren, 2018, In: Arthritis & rheumatology (Hoboken, N.J.). 70, 6, p. 878-890 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    TET2 mutations are associated with hypermethylation at key regulatory enhancers in normal and malignant hematopoiesis

    Tulstrup, Morten Rytter, Soerensen, M., Hansen, Jakob Werner, Gillberg, Linn, Needhamsen, M., Kaastrup, K., Helin, K., Christensen, K., Weischenfeldt, Joachim Lütken & Grønbæk, Kirsten, 2021, In: Nature Communications. 12, 1, 10 p., 6061.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A predictive model for bone marrow disease in cytopenia based on noninvasive procedures

    Træden, D., Tulstrup, M., Cowland, J. B., Sjö, Lene Dissing, Bøgsted, M., Grønbæk, Kirsten, Andersen, M. K. & Hansen, J. W., 2022, In: Blood advances. 6, 11, p. 3541-3550

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Overall Survival in Patients with Ccus Depends on Presence of Anemia

    Træden, D., Tulstrup, Morten Rytter, Johansen, M. M., Ørskov, A. D., Marcher, C., Raaschou-jensen, K., Stidsholt Roug, A., Severinsen, M. T., Porse, Bo Torben, Theilgaard-mönch, K., Jespersen, Jakob Schmidt, Cowland, J. B., Sjö, Lene Dissing, Andersen, M. K., Grønbæk, Kirsten & Hansen, J. W., 2023, In: Blood. 142, Suppl. 1, p. 1864-1865

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  15. Published

    Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML

    Treppendahl, M. B., Qiu, X., Søgaard, A., Yang, X., Nandrup-Bus, C., Hother, C., Andersen, M. K., Kjeldsen, L., Möllgård, L., Möllgaard, L., Hellström-Lindberg, E., Jendholm, L. J., Porse, Bo Torben, Jones, P. A., Liang, G. & Grønbæk, Kirsten, 5 Jan 2012, In: Blood. 119, 1, p. 206-16 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Predicting response to epigenetic therapy

    Treppendahl, M. B., Sommer Kristensen, L. & Grønbæk, Kirsten, Jan 2014, In: The Journal of Clinical Investigation. 124, 1, p. 47-55 9 p.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes

    Trempenau, M. L., Schuster, Mikkel Bruhn, Pundhir, Sachin, Araújo Pereira, Mafalda, Kalvisa, A., Tapia, Marta Cecylia, Su, Jinyu, Ge, Y., de Boer, Bauke, Balhuizen, Alexander, Bagger, F. O., Shliaha, P., Sroczynska, P., Walfridsson, J., Grønbæk, Kirsten, Theilgaard-Mønch, Kim, Jensen, O. N., Helin, K. & Porse, Bo Torben, 2023, In: Leukemia. 37, 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Second primary malignancies in patients with lymphoma in Denmark after high-dose chemotherapy and autologous haematopoietic stem-cell transplantation: a population-based, retrospective cohort study

    Trab, Trine, Baech, J., Jakobsen, L. H., Husby, S., Severinsen, M. T., Eloranta, S., Gørløv, J. S., Jørgensen, J. M., Gudbrandsdottir, S., Larsen, T. S., Brown, Peter de Nully, Grønbæk, Kirsten, Smedby, K. E. & El-Galaly, T. C., 2023, In: The Lancet Haematology. 10, 10, p. e838-e848 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    A novel del(8)(q23.2q24.11) contributing to disease progression in a case of JAK2/TET2 double mutated chronic myelomonocytic leukemia

    Toft-Petersen, M., Kjeldsen, E., Nederby, L., Grønbæk, Kirsten, Hokland, P. & Roug, A. S., 2014, In: Leukemia Research Reports. 3, 2, p. 94-97 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Endogenous Retroviral Elements Constitute a Promising Vaccine Antigen Source for Haematological Malignancies

    Thygesen, Christian Bahne, Klausen, M. S., Thuesen, N., Garde, C., Jespersen, A., Grønbæk, Kirsten, Kringelum, J. & Bundgård Sørensen, A. B., 28 Nov 2023, In: Blood. 142, Supplement 1, p. 243-243

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    ProGraME: A novel flow cytometry algorithm for the diagnosis of low-risk myelodysplastic syndromes in patients with cytopenia

    Therkelsen, J., Træden, D. W., Schjødt, I., Andersen, M. K., Sjö, Lene Dissing, Hansen, Jakob Werner, Grønbæk, Kirsten & Dimopoulos, K., 2023, In: European Journal of Haematology. 111, 6, 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Immune-monitoring of myelodysplastic neoplasms: Recommendations from the i4MDS consortium

    i4MDS consortium, I. C., 2024, In: HemaSphere. 8, 5, 16 p., e64.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Clonal Hematopoiesis and Epigenetic Age Acceleration in Elderly Danish Twins

    Sørensen, M., Tulstrup, Morten Rytter, Hansen, Jakob Werner, Weischenfeldt, Joachim Lütken, Grønbæk, Kirsten & Christensen, K., 2022, In: HemaSphere. 6, 9, 6 p., 768.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The Thioredoxin-Interacting Protein TXNIP Is a Putative Tumour Suppressor in Cutaneous T-Cell Lymphoma

    Stolearenco, V., Levring, T. B., Nielsen, H. M., Lindahl, L., Fredholm, S., Kongsbak-Wismann, Martin, Willerslev-Olsen, A., Buus, Terkild Brink, Nastasi, C., Hu, T., Gluud, Maria, Côme, Christophe Roger Michel, Krejsgaard, T., Iversen, L., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Met, Özcan, Woetmann, Anders , Ødum, Niels & Geisler, Carsten, 2021, In: Dermatology. 237, 2, p. 283-290 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    A novel splice mutation in the TP53 gene associated with Leydig cell tumor and primitive neuroectodermal tumor

    Stecher, C. W., Hasle, H. & Grønbæk, Kirsten, 2008, In: Pediatric Blood & Cancer. 50, 3, p. 701-703 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 37722667