Kirsten Grønbæk
Clinical Professor
Department of Clinical Medicine
Blegdamsvej 3
2200 København N.
Member of:
Internal Medicine: Haematology
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DNA Methyltransferase Inhibitors in Myeloid Cancer: Clonal Eradication or Clonal Differentiation?
mxz703, mxz703 & Grønbæk, Kirsten, Sep 2017, In: Cancer journal (Sudbury, Mass.). 23, 5, p. 277-285 9 p.Research output: Contribution to journal › Review › Research › peer-review
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Hypomethylation and up-regulation of PD-1 in T cells by azacytidine in MDS/AML patients: A rationale for combined targeting of PD-1 and DNA methylation
mxz703, mxz703, Treppendahl, M. B., Skovbo, A., Holm, M. S., Friis, L. S., Hokland, M. & Grønbæk, Kirsten, 2015, In: OncoTarget. 6, 11, p. 9612-26 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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How a Medical Association Can Make a Difference in a Crisis Situation
van Havre, N., Orsini, E., Almeida, A., Gribben, J., Bolanos, N., Doeswijk, R., Gaidano, G., Mouhssine, S., Doehner, K., Grønbæk, Kirsten, Porkka, K. & Macintyre, E., 2022, In: HemaSphere. 6, 9, 3 p., 765.Research output: Contribution to journal › Editorial › Research › peer-review
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Risk of new malignancies among patients with CLL treated with chemotherapy: results of a Danish population-based study
da Cunha-Bang, C., Rostgaard, K., Andersen, M. A., Rotbain, E. C., Grønbæk, Kirsten, Frederiksen, H., Niemann, Carsten & Hjalgrim, Henrik, 2021, In: British Journal of Haematology. 193, 2, p. 339-345Research output: Contribution to journal › Journal article › Research › peer-review
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Allogeneic Hematopoietic Stem Cell Transplantation for Chronic Myelomonocytic Leukemia: Clinical and Molecular Genetic Prognostic Factors in a Nordic Population
Wedge, E., Hansen, J. W., Dybedal, I., Creignou, M., Ejerblad, E., Lorenz, F., Werlenius, O., Ungerstedt, J., Holm, M. S., Nilsson, L., Kittang, A. O., Antunovic, P., Rohon, P., Andersen, M. K., Papaemmanuil, E., Bernard, E., Jädersten, M., Hellström-Lindberg, E., Grønbæk, K., Ljungman, P. & 1 others, , 2021, In: Transplantation and Cellular Therapy. 27, 12, p. 991.e1-991.e9Research output: Contribution to journal › Journal article › Research › peer-review
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Improved Outcomes after Allogenic Hematopoietic Stem Cell Transplantation with Fludarabine/Treosulfan for Patients with Myelodysplastic Syndromes
Wedge, E., Sengeløv, Henrik, Hansen, Jakob Werner, Andersen, N. S., Schjødt, I., Petersen, S. L., Kornblit, B., Grønbæk, Kirsten & Friis, L. S., 2020, In: Biology of Blood and Marrow Transplantation. 26, 6, p. 1091-1098Research output: Contribution to journal › Journal article › Research › peer-review
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Global hypomethylation is an independent prognostic factor in diffuse large B cell lymphoma
Wedge, E., Hansen, Jakob Werner, Garde, C., Asmar, F., Tholstrup, Dorte Maegaard, Kristensen, S. S., Munch-Petersen, H. D., Ralfkiaer, E., Brown, Peter de Nully, Grønbæk, Kirsten & Kristensen, L. S., Jul 2017, In: American Journal of Hematology. 92, 7, p. 689-694 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of U2AF1 mutations on circular RNA expression in myelodysplastic neoplasms
Wedge, E., Ahmadov, U., Hansen, T. B., Gao, Z., Tulstrup, Morten Rytter, Côme, Christophe Roger Michel, Nonavinkere Srivatsan, S., Ahmed, T., Jespersen, Jakob Schmidt, Schlotmann, Balthasar Clemens, Schöllkopf, C., Raaschou-Jensen, K., Ødum, Niels, Kjems, J., Bak, R. O., Walter, M. J., Grønbæk, Kirsten & Kristensen, L. S., 2023, In: Leukemia. 37, p. 1113-1125Research output: Contribution to journal › Journal article › Research › peer-review
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Angiotensinogen promoter methylation predicts bevacizumab treatment response of patients with recurrent glioblastoma
Urup, T., Gillberg, Linn, Kaastrup, K., Lü, M. J. S., Michaelsen, Signe Regner, Andrée Larsen, V., Christensen, I. J., Broholm, H., Lassen, Ulrik Niels, Grønbæk, Kirsten & Poulsen, H. S., 2020, In: Molecular Oncology. 14, 5, p. 964-973Research output: Contribution to journal › Journal article › Research › peer-review
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Angiotensinogen promoter methylation to predict bevacizumab response in recurrent glioblastoma patients
Urup, T., Gillberg, Linn, Kaastrup, K., Lu, M. S., Michaelsen, Signe Regner, Larsen, V. A., Christensen, I. J., Broholm, H., Lassen, Ulrik Niels, Grønbæk, Kirsten & Poulsen, H. S., 2019, In: Neuro-Oncology. 21, Supplement 6, p. vi149Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Twin DNA Methylation Profiling Reveals Flare-Dependent Interferon Signature and B Cell Promoter Hypermethylation in Systemic Lupus Erythematosus
Ulff-Møller, C. J., Asmar, F., Liu, Y., Svendsen, A. J., Busato, F., Grønbæk, Kirsten, Tost, J. & Jacobsen, Søren, 2018, In: Arthritis & rheumatology (Hoboken, N.J.). 70, 6, p. 878-890 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TET2 mutations are associated with hypermethylation at key regulatory enhancers in normal and malignant hematopoiesis
Tulstrup, Morten Rytter, Soerensen, M., Hansen, Jakob Werner, Gillberg, Linn, Needhamsen, M., Kaastrup, K., Helin, K., Christensen, K., Weischenfeldt, Joachim Lütken & Grønbæk, Kirsten, 2021, In: Nature Communications. 12, 1, 10 p., 6061.Research output: Contribution to journal › Journal article › Research › peer-review
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A predictive model for bone marrow disease in cytopenia based on noninvasive procedures
Træden, D., Tulstrup, M., Cowland, J. B., Sjö, Lene Dissing, Bøgsted, M., Grønbæk, Kirsten, Andersen, M. K. & Hansen, J. W., 2022, In: Blood advances. 6, 11, p. 3541-3550Research output: Contribution to journal › Journal article › Research › peer-review
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Overall Survival in Patients with Ccus Depends on Presence of Anemia
Træden, D., Tulstrup, Morten Rytter, Johansen, M. M., Ørskov, A. D., Marcher, C., Raaschou-jensen, K., Stidsholt Roug, A., Severinsen, M. T., Porse, Bo Torben, Theilgaard-mönch, K., Jespersen, Jakob Schmidt, Cowland, J. B., Sjö, Lene Dissing, Andersen, M. K., Grønbæk, Kirsten & Hansen, J. W., 2023, In: Blood. 142, Suppl. 1, p. 1864-1865Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Allelic methylation levels of the noncoding VTRNA2-1 located on chromosome 5q31.1 predict outcome in AML
Treppendahl, M. B., Qiu, X., Søgaard, A., Yang, X., Nandrup-Bus, C., Hother, C., Andersen, M. K., Kjeldsen, L., Möllgård, L., Möllgaard, L., Hellström-Lindberg, E., Jendholm, L. J., Porse, Bo Torben, Jones, P. A., Liang, G. & Grønbæk, Kirsten, 5 Jan 2012, In: Blood. 119, 1, p. 206-16 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Predicting response to epigenetic therapy
Treppendahl, M. B., Sommer Kristensen, L. & Grønbæk, Kirsten, Jan 2014, In: The Journal of Clinical Investigation. 124, 1, p. 47-55 9 p.Research output: Contribution to journal › Review › Research › peer-review
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The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes
Trempenau, M. L., Schuster, Mikkel Bruhn, Pundhir, Sachin, Araújo Pereira, Mafalda, Kalvisa, A., Tapia, Marta Cecylia, Su, Jinyu, Ge, Y., de Boer, Bauke, Balhuizen, Alexander, Bagger, F. O., Shliaha, P., Sroczynska, P., Walfridsson, J., Grønbæk, Kirsten, Theilgaard-Mønch, Kim, Jensen, O. N., Helin, K. & Porse, Bo Torben, 2023, In: Leukemia. 37, 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Second primary malignancies in patients with lymphoma in Denmark after high-dose chemotherapy and autologous haematopoietic stem-cell transplantation: a population-based, retrospective cohort study
Trab, Trine, Baech, J., Jakobsen, L. H., Husby, S., Severinsen, M. T., Eloranta, S., Gørløv, J. S., Jørgensen, J. M., Gudbrandsdottir, S., Larsen, T. S., Brown, Peter de Nully, Grønbæk, Kirsten, Smedby, K. E. & El-Galaly, T. C., 2023, In: The Lancet Haematology. 10, 10, p. e838-e848 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A novel del(8)(q23.2q24.11) contributing to disease progression in a case of JAK2/TET2 double mutated chronic myelomonocytic leukemia
Toft-Petersen, M., Kjeldsen, E., Nederby, L., Grønbæk, Kirsten, Hokland, P. & Roug, A. S., 2014, In: Leukemia Research Reports. 3, 2, p. 94-97 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Endogenous Retroviral Elements Constitute a Promising Vaccine Antigen Source for Haematological Malignancies
Thygesen, Christian Bahne, Klausen, M. S., Thuesen, N., Garde, C., Jespersen, A., Grønbæk, Kirsten, Kringelum, J. & Bundgård Sørensen, A. B., 28 Nov 2023, In: Blood. 142, Supplement 1, p. 243-243Research output: Contribution to journal › Journal article › Research › peer-review
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ProGraME: A novel flow cytometry algorithm for the diagnosis of low-risk myelodysplastic syndromes in patients with cytopenia
Therkelsen, J., Træden, D. W., Schjødt, I., Andersen, M. K., Sjö, Lene Dissing, Hansen, Jakob Werner, Grønbæk, Kirsten & Dimopoulos, K., 2023, In: European Journal of Haematology. 111, 6, 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Immune-monitoring of myelodysplastic neoplasms: Recommendations from the i4MDS consortium
i4MDS consortium, I. C., 2024, In: HemaSphere. 8, 5, 16 p., e64.Research output: Contribution to journal › Journal article › Research › peer-review
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Clonal Hematopoiesis and Epigenetic Age Acceleration in Elderly Danish Twins
Sørensen, M., Tulstrup, Morten Rytter, Hansen, Jakob Werner, Weischenfeldt, Joachim Lütken, Grønbæk, Kirsten & Christensen, K., 2022, In: HemaSphere. 6, 9, 6 p., 768.Research output: Contribution to journal › Journal article › Research › peer-review
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The Thioredoxin-Interacting Protein TXNIP Is a Putative Tumour Suppressor in Cutaneous T-Cell Lymphoma
Stolearenco, V., Levring, T. B., Nielsen, H. M., Lindahl, L., Fredholm, S., Kongsbak-Wismann, Martin, Willerslev-Olsen, A., Buus, Terkild Brink, Nastasi, C., Hu, T., Gluud, Maria, Côme, Christophe Roger Michel, Krejsgaard, T., Iversen, L., Bonefeld, Charlotte Menne, Grønbæk, Kirsten, Met, Özcan, Woetmann, Anders , Ødum, Niels & Geisler, Carsten, 2021, In: Dermatology. 237, 2, p. 283-290 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A novel splice mutation in the TP53 gene associated with Leydig cell tumor and primitive neuroectodermal tumor
Stecher, C. W., Hasle, H. & Grønbæk, Kirsten, 2008, In: Pediatric Blood & Cancer. 50, 3, p. 701-703 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 37722667
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2554
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miR-449 inhibits cell proliferation and is down-regulated in gastric cancer
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
417
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Specific Lipid and Metabolic Profiles of R-CHOP-Resistant Diffuse Large B-Cell Lymphoma Elucidated by Matrix-Assisted Laser Desorption Ionization Mass Spectrometry Imaging and in Vivo Imaging
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
386
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TP53 hotspot mutations are predictive of survival in primary central nervous system lymphoma patients treated with combination chemotherapy
Research output: Contribution to journal › Journal article › Research
Published