Anne Tybjærg-Hansen
Clinical Professor
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Repositioning of the global epicentre of non-optimal cholesterol
NCD Risk Factor Collaboration (NCD-RisC), N. R. F. C. (., Taddei, C., Zhou, B., Bixby, H., Nordestgaard, Børge, Benn, Marianne, Linneberg, Allan René, Tybjærg-Hansen, Anne, Cisneros, J. Z., Gregg, E. W., Ezzati, M. & Sørensen, Thorkild I.A., 2020, In: Nature. 582, 7810, p. 73-77Research output: Contribution to journal › Journal article › Research › peer-review
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Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
EADB contributors, E. C., The GR@ACE study group, T. G. S. G., DEGESCO consortium, D. C., IGAP (ADGC, CHARGE, EADI, GERAD), I. (. C. E. G. & PGC-ALZ consortia, P. C., Dec 2021, In: Nature Communications. 12, 1, 16 p., 3417.Research output: Contribution to journal › Journal article › Research › peer-review
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Identification of new susceptibility loci for type 2 diabetes and shared etiological pathways with coronary heart disease
Zhao, W., Rasheed, A., Tikkanen, E., Lee, J-J., Butterworth, A. S., Howson, J. M. M., Assimes, T. L., Chowdhury, R., Orho-Melander, M., Damrauer, S., Small, A., Asma, S., Imamura, M., Yamauch, T., Chambers, J. C., Chen, P., Sapkota, B. R., Shah, N., Jabeen, S., Surendran, P. & 31 others, , Oct 2017, In: Nature Genetics. 49, 10, p. 1450-1457 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rare variant in scavenger receptor BI raises HDL cholesterol and increases risk of coronary heart disease
CHD Exome+ Consortium, C. E. C., CARDIoGRAM Exome Consortium, C. E. C. & Global Lipids Genetics Consortium, G. L. G. C., 11 Mar 2016, In: Science (New York, N.Y.). 351, 6278, p. 1166-71 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Posttranscriptional Regulation of the Human LDL Receptor by the U2-Spliceosome
Zanoni, P., Panteloglou, G., Othman, A., Haas, J. T., Meier, R., Rimbert, A., Futema, M., Khalil, Y. A., Norrelykke, S. F., Rzepiela, A. J., Stoma, S., Stebler, M., Van Dijk, F., Wijers, M., Wolters, J. C., Dalila, N., Huijkman, N. C. A., Smit, M., Gallo, A., Carreau, V. & 26 others, , 2022, In: Circulation Research. 130, 1, p. 80-95 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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C-reactive protein and all-cause mortality--the Copenhagen City Heart Study
Zacho, J., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 Jul 2010, In: European Heart Journal. 31, 13, p. 1624-32 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hyperhomocysteinemia, methylenetetrahydrofolate reductase c.677C>T polymorphism and risk of cancer: cross-sectional and prospective studies and meta-analyses of 75,000 cases and 93,000 controls
Zacho, J., Yazdanyar, S., Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2011, In: International Journal of Cancer. 128, 3, p. 644-52 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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C-reaktivt protein og risiko for iskæmisk hjerte- og cerebrovaskulær sygdom - sekundærpublikation
Zacho, J., Tybjærg-Hansen, Anne, Jensen, J. S., Grande, P., Sillesen, Henrik & Nordestgaard, Børge, 2009, In: Ugeskrift for læger. 171, p. 1751-1755Research output: Contribution to journal › Journal article › Research › peer-review
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C-reactive protein, genetically elevated levels and risk of ischemic heart and cerebrovascular disease
Zacho, J., Tybjærg-Hansen, Anne & Nordestgaard, B. G., 2009, In: Scandinavian Journal of Clinical & Laboratory Investigation. 69, 4, p. 442-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Increased Baseline C-Reactive Protein Concentrations Are Associated with Increased Risk of Infections: Results from 2 Large Danish Population Cohorts
Zacho, J., Benfield, Thomas, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Feb 2016, In: Clinical Chemistry. 62, 2, p. 335-42 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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C-reactive protein and risk of venous thromboembolism in the general population
Zacho, J., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 Aug 2010, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 30, 8, p. 1672-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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C-reaktivt protein og risiko for iskaemisk hjerte- og cerebrovaskulaer sygdom--sekundaerpublikation
Zacho, J., Tybjærg-Hansen, Anne, Jensen, J. S., Grande, P., Sillesen, Henrik & Nordestgaard, B. G., 2009, In: Ugeskrift for læger. 171, 21, p. 1751-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetically elevated C-reactive protein and ischemic vascular disease
Zacho, J., Tybjærg-Hansen, Anne, Jensen, J. S., Grande, P., Sillesen, Henrik & Nordestgaard, B. G., 2008, In: New England Journal of Medicine. 359, 18, p. 1897-1908 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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[C-reactive protein and risk of ischaemic vascular and cerebrovascular disease--secondary publication]
Zacho, J., Tybjærg-Hansen, Anne, Jensen, J. S., Grande, P., Sillesen, Henrik & Nordestgaard, B. G., 2009, In: Ugeskrift for læger. 171, 21, p. 1751-1755 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Penetrance of NOD2/CARD15 genetic variants in the general population
Yazdanyar, S., Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 20 Apr 2010, In: C M A J. 182, 7, p. 661-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Steroid receptor coactivator-1 modulates the function of Pomc neurons and energy homeostasis
Yang, Y., van der Klaauw, A. A., Zhu, L., Cacciottolo, T. M., He, Y., Stadler, L. K. J., Wang, C., Xu, P., Saito, K., Hinton, A., Yan, X., Keogh, J. M., Henning, E., Banton, M. C., Hendricks, A. E., Bochukova, E. G., Mistry, V., Lawler, K. L., Liao, L., Xu, J. & 306 others, , 2019, In: Nature Communications. 10, 14 p., 1718.Research output: Contribution to journal › Journal article › Research › peer-review
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SCARB1 Gene Variants Are Associated With the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a)
Yang, X., Sethi, A. A., Yanek, L. R., Knapper, C., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Becker, D. M., Mathias, R. A., Remaley, A. T. & Becker, L. C., Oct 2016, In: Circulation: Cardiovascular Genetics. 9, 5, p. 408-418 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipoprotein Subclass Profiling Reveals Pleiotropy in the Genetic Variants of Lipid Risk Factors for Coronary Heart Disease: A Note on Mendelian Randomization Studies
Würtz, P., Kangas, A. J., Soininen, P., Lehtimäki, T., Kähönen, M., Viikari, J. S., Raitakari, O. T., Järvelin, M., Davey Smith, G., Ala-Korpela, M., Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2013, In: Journal of the American College of Cardiology. 62, 20, p. 1906-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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APOC3 Loss-of-Function Mutations, Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Cardiovascular Risk: Mediation- and Meta-Analyses of 137 895 Individuals
Wulff, A. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 3, p. 660-668Research output: Contribution to journal › Journal article › Research › peer-review
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Separate and combined associations of body-mass index and abdominal adiposity with cardiovascular disease: collaborative analysis of 58 prospective studies
Wormser, D., Kaptoge, S., Di Angelantonio, E., Wood, A. M., Pennells, L., Thompson, A., Sarwar, N., Kizer, J. R., Lawlor, D. A., Nordestgaard, B. G., Ridker, P., Salomaa, V., Stevens, J., Woodward, M., Sattar, N., Collins, R., Thompson, S. G., Whitlock, G., Danesh, J., Emerging Risk Factors Collaboration & 2 others, , 2011, In: Lancet. 377, 9771, p. 1085-95 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Combined analysis of six lipoprotein lipase genetic variants on triglycerides, high-density lipoprotein, and ischemic heart disease: cross-sectional, prospective, and case-control studies from the Copenhagen City Heart Study
Wittrup, H. H., Andersen, R. V., Tybjærg-Hansen, Anne, Jensen, G. B. & Nordestgaard, Børge, 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 4, p. 1438-45 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Combined analysis of six lipoprotein lipase genetic variants on triglycerides, high-density lipoprotein, and ischemic heart disease: cross-sectional, prospective, and case-control studies from the Copenhagen City Heart Study.
Wittrup, H., Andersen, R., Tybjærg-Hansen, A., Jensen, G. B., Nordestgaard, B. & Tybjærg-Hansen, Anne, 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 4, p. 1438-45Research output: Contribution to journal › Journal article › Research › peer-review
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Familial hypercholesterolaemia in children and adolescents: gaining decades of life by optimizing detection and treatment
Wiegman, A., Gidding, S. S., Watts, G. F., Chapman, M. J., Ginsberg, H. N., Cuchel, M., Ose, L., Averna, M., Boileau, C., Borén, J., Bruckert, E., Catapano, A. L., Defesche, J. C., Descamps, O. S., Hegele, R. A., Hovingh, G. K., Humphries, S. E., Kovanen, P. T., Kuivenhoven, J. A., Masana, L. & 13 others, , 21 Sep 2015, In: European Heart Journal. 36, 36, p. 2425-37 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data
Wensley, F., Gao, P., Burgess, S., Kaptoge, S., Di Angelantonio, E., Shah, T., Engert, J. C., Clarke, R., Davey-Smith, G., Nordestgaard, B. G., Saleheen, D., Samani, N. J., Sandhu, M., Anand, S., Pepys, M. B., Smeeth, L., Whittaker, J., Casas, J. P., Thompson, S. G., Hingorani, A. D. & 3 others, , 2011, In: B M J. 342, p. d548Research output: Contribution to journal › Journal article › Research › peer-review
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CHEK2*1100delC genotyping for clinical assessment of breast cancer risk: meta-analyses of 26,000 patient cases and 27,000 controls
Weischer, M., Bojesen, Stig Egil, Ellervik, C., Tybjærg-Hansen, Anne & Nordestgaard, B. G., 2008, In: Journal of Clinical Oncology. 26, 4, p. 542-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Short Telomere Length, Myocardial Infarction, Ischemic Heart Disease, and Early Death
Weischer, M., Bojesen, Stig Egil, Cawthon, R. M., Freiberg, J. J., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 32, p. 822-29Research output: Contribution to journal › Journal article › Research › peer-review
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Prothrombin and risk of venous thromboembolism, ischemic heart disease and ischemic cerebrovascular disease in the general population
Weischer, M., Juul, K., Zacho, J., Jensen, G. B., Steffensen, R., Schroeder, T. V., Tybjærg-Hansen, Anne, Nordestgaard, B. G., Weischer, M., Juul, K., Zacho, J., Jensen, G. B., Steffensen, R., Schroeder, T. V., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 Feb 2010, In: Atherosclerosis. 208, 2, p. 480-3 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Short telomere length, cancer survival, and cancer risk in 47102 individuals
Weischer, M., Nordestgaard, Børge, Cawthon, R. M., Freiberg, J. J., Tybjærg-Hansen, Anne & Bojesen, S. E., 3 Apr 2013, In: National Cancer Institute. Journal (Print). 105, 7, p. 459-68 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium
Wassel, C. L., Lamina, C., Nambi, V., Coassin, S., Mukamal, K. J., Ganesh, S. K., Jacobs, D. R., Franceschini, N., Papanicolaou, G. J., Gibson, Q., Yanek, L. R., van der Harst, P., Ferguson, J. F., Crawford, D. C., Waite, L. L., Allison, M. A., Criqui, M. H., McDermott, M. M., Mehra, R., Cupples, L. A. & 41 others, , 2012, In: Atherosclerosis. 222, 1, p. 138-47 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The UK10K project identifies rare variants in health and disease
Walter, K., Min, J. L., Huang, J., Crooks, L., Memari, Y., McCarthy, S., Perry, J. R. B., Xu, C., Futema, M., Lawson, D., Iotchkova, V., Schiffels, S., Hendricks, A. E., Danecek, P., Li, R., Floyd, J., Wain, L. V., Barroso, I., Humphries, S. E., Hurles, M. E. & 319 others, , 2015, In: Nature. 526, 7571, p. 82-90 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
Voight, B. F., Peloso, G. M., Orho-Melander, M., Frikke-Schmidt, R., Barbalic, M., Jensen, M. K., Hindy, G., Hólm, H., Ding, E. L., Johnson, T., Schunkert, H., Samani, N. J., Clarke, R., Hopewell, J. C., Thompson, J. F., Li, M., Thorleifsson, G., Newton-Cheh, C., Musunuru, K., Pirruccello, J. P. & 106 others, , 2012, In: Lancet. 380, 9841, p. 572-80 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Remnant cholesterol as a causal risk factor for ischemic heart disease
Varbo, A., Benn, M., Tybjærg-Hansen, Anne, Jørgensen, A. B., Frikke-Schmidt, R. & Nordestgaard, Børge, 2013, In: Journal of the American College of Cardiology. 61, 4, p. 427-36 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Blood Pressure as Mediators From Obesity to Ischemic Heart Disease
Varbo, A., Benn, Marianne, Smith, G. D., Timpson, N. J., Tybjærg-Hansen, Anne & Nordestgaard, Børge, Feb 2015, In: Circulation Research. 116, 4, p. 665-673 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonfasting triglycerides, cholesterol, and ischemic stroke in the general population
Varbo, A., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Schnohr, P., Jensen, G. B., Benn, M. & Benn, M., 1 Apr 2011, In: Annals of Neurology. 69, 4, p. 628-34 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Elevated Remnant Cholesterol Causes Both Low-Grade Inflammation and Ischemic Heart Disease, Whereas Elevated Low-Density Lipoprotein Cholesterol Causes Ischemic Heart Disease Without Inflammation
Varbo, A., Benn, Marianne, Tybjærg-Hansen, Anne, Nordestgaard, Børge & Benn, Marianne, 2013, In: Circulation. 128, 12, p. 1298-1309 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TRIB1 and GCKR polymorphisms, lipid levels, and risk of ischemic heart disease in the general population
Varbo, A., Benn, M., Tybjærg-Hansen, Anne, Grande, P., Nordestgaard, Børge & Benn, M., 2011, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 31, 2, p. 451-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Global perspective of familial hypercholesterolaemia: a cross-sectional study from the EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)
Vallejo-Vaz, A. J., Stevens, C. A. T., Lyons, A. R. M., Dharmayat, K. I., Freiberger, T., Hovingh, G. K., Mata, P., Raal, F. J., Santos, R. D., Soran, H., Watts, G. F., Abifadel, M., Aguilar-Salinas, C. A., Alhabib, K. F., Alkhnifsawi, M., Almahmeed, W., Alnouri, F., Alonso, R., Al-Rasadi, K., Al-Sarraf, A. & 31 others, , 2021, In: The Lancet. 398, 10312, p. 1713-1725 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Overview of the current status of familial hypercholesterolaemia care in over 60 countries - The EAS Familial Hypercholesterolaemia Studies Collaboration (FHSC)
Vallejo-Vaz, A. J., Marco, M. D., Stevens, C. A. T., Akram, A., Freiberger, T., Hovingh, G. K., Kastelein, J. J. P., Mata, P., Raal, F. J., Santos, R. D., Soran, H., Watts, G. F., Abifadel, M., Aguilar Salinas, C. A., Al-Khnifsawi, M., Alkindi, F. A., Alnouri, F., Alonso, R., Al-Rasadi, K., Al-Sarraf, A. & 248 others, , 2018, In: Atherosclerosis. 277, p. 234-255 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pharmacogenetics-guided CETP inhibition: an open question?
Tybjærg-Hansen, Anne, Nordestgaard, L. T. & Christoffersen, M., 2022, In: European Heart Journal. 43, 39, p. 3957-3959 3 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Using Human Genetics to Predict the Effects and Side Effects of Lipoprotein(a) Lowering Drugs
Tybjærg-Hansen, Anne, Dec 2016, In: Journal of the American College of Cardiology. 68, 25, p. 2773-2775 3 p.Research output: Contribution to journal › Comment/debate › Research
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Mendelsk randomisering - eller hvordan man kan bruge gener til at sandsynliggøre kausalitet.
Tybjærg-Hansen, Anne, May 2010, In: DSKB-Nyt. 2, p. 18-21 4 p.Research output: Contribution to journal › Journal article › Research
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Triglyceride-rich remnant lipoproteins are more atherogenic than LDL per particle: is this important?
Tybjærg-Hansen, Anne, Nordestgaard, Børge & Christoffersen, M., 2023, In: European Heart Journal. 44, 39, p. 4196-4198 3 p.Research output: Contribution to journal › Review › Research › peer-review
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Adult height and the risk of cause-specific death and vascular morbidity in 1 million people: individual participant meta-analysis
Tybjærg-Hansen, Anne, Jørgensen, T. & Emerging Risk Factors Collaboration, E. R. F. C., 2012, In: International Journal of Epidemiology. 41, 5, p. 1419-33 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Sialylation Pathway and Coronary Artery Disease
Tybjærg-Hansen, Anne, 2 Jun 2016, In: New England Journal of Medicine. 374, 22, p. 2169-2171 3 p.Research output: Contribution to journal › Editorial › Research
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Correcting for multivariate measurement error by regression calibration in meta-analyses of epidemiological studies
Tybjærg-Hansen, Anne, 2009, In: Statistics in Medicine. 28, 7, p. 1067-1092 25 p.Research output: Contribution to journal › Journal article › Research
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Phenotype of heterozygotes for low-density lipoprotein receptor mutations identified in different background populations
Tybjærg-Hansen, Anne, Jensen, H. K., Benn, M., Steffensen, R., Jensen, G. & Nordestgaard, Børge, 2005, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 25, 1, p. 211-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonfasting Triglycerides remnant lipoproteins, and cardiovascular disease
Tybjærg-Hansen, Anne, Nordestgaard, B. G. & Nordestgaard, Børge, 2009, In: Klinisk Kemi i Norden. 21, 3, p. 10-16 7 p.Research output: Contribution to journal › Journal article › Research
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Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Turcot, V., Lu, Y., Highland, H. M., Bang, L. E., Benn, M., Kamstrup, P. R., Bork-Jensen, J., Frikke-Schmidt, R., Gjesing, A. P., Grarup, N., Hansen, T., Have, C. T., Jørgensen, T., Nielsen, S. F., Linneberg, A. R., Pedersen, O., Pers, T. H., Vestergaard, H., Nordestgaard, B., Tybjærg-Hansen, A. & 15 others, , 1 Jan 2018, In: Nature Genetics. 50, p. 26-41 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inhibition of Cholesteryl Ester Transfer Protein Preserves High-Density Lipoprotein Cholesterol and Improves Survival in Sepsis
Trinder, M., Wang, Y., Madsen, C. M., Ponomarev, T., Bohunek, L., Daisley, B. A., Kong, H. J., Blauw, L. L., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Wurfel, M. M., Russell, J. A., Walley, K. R., Rensen, P. C. N., Boyd, J. H. & Brunham, L. R., 2021, In: Circulation. 143, 9, p. 921–934Research output: Contribution to journal › Journal article › Research › peer-review
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Alcoholism and alcohol drinking habits predicted from alcohol dehydrogenase genes
Tolstrup, J. S., Nordestgaard, Børge, Rasmussen, S., Tybjærg-Hansen, Anne & Gronbaek, M., 2008, In: Pharmacogenomics Journal. 8, 3, p. 220-227 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetisk variation i alkoholdehydrogenase, alkoholdrikkevaner og alkoholisme--sekundaerpublikation
Tolstrup, J. S., Nordestgaard, B. G., Rasmussen, S., Tybjærg-Hansen, Anne & Gronbaek, M., 2008, In: Ugeskrift for læger. 170, 35, p. 2672-2675 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Alcohol intake, alcohol dehydrogenase genotypes, and liver damage and disease in the Danish general population
Tolstrup, J. S., Gronbaek, M., Tybjærg-Hansen, Anne & Nordestgaard, B. G., 2009, In: American Journal of Gastroenterology. 104, 9, p. 2182-2188 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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[Genetic variations in alcohol dehydrogenase, drinking habits and alcoholism]
Tolstrup, J. S., Rasmussen, S., Tybjærg-Hansen, Anne, Gronbaek, M. & Nordestgaard, Børge, 2008, In: Ugeskrift for læger. 170, 35, p. 2672-2675 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Does greater adiposity increase blood pressure and hypertension risk?: Mendelian randomization using the FTO/MC4R genotype
Timpson, N. J., Harbord, R., Davey Smith, G., Zacho, J., Tybjærg-Hansen, Anne & Nordestgaard, B. G., 2009, In: Hypertension. 54, 1, p. 84-90 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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C-reactive protein levels and body mass index: elucidating direction of causation through reciprocal Mendelian randomization
Timpson, N. J., Nordestgaard, Børge, Harbord, R. M., Zacho, J., Frayling, T. M., Tybjærg-Hansen, Anne, Smith, G. D. & Smith, G. D., 1 Feb 2011, In: International Journal of Obesity. 35, 2, p. 300-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Scavenger receptor AI/II truncation, lung function and COPD in 48,700 individuals: Abstracts - other lecturers
Thomsen, M., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Dahl, Morten, Oct 2011, In: The Clinical Respiratory Journal.Research output: Contribution to journal › Journal article › Research › peer-review
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ß2-adrenergic receptor Thr164Ile polymorphism, obesity, and diabetes: comparison with FTO, MC4R, and TMEM18 polymorphisms in more than 64,000 individuals
Thomsen, M., Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 6, p. E1074-9Research output: Contribution to journal › Journal article › Research › peer-review
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Splice site mutations in mismatch repair genes and risk of cancer in the general population
Thomsen, M., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Bojesen, S. E., 18 Jan 2013, In: Familial Cancer.Research output: Contribution to journal › Journal article › Research › peer-review
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β2-adrenergic receptor Thr164Ile polymorphism, obesity, and diabetes: comparison with FTO, MC4R, and TMEM18 polymorphisms in more than 64,000 individuals
Thomsen, M., Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 6, p. E1074-9Research output: Contribution to journal › Journal article › Research › peer-review
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Low Nonfasting Triglycerides and Reduced All-Cause Mortality: A Mendelian Randomization Study
Thomsen, M., Varbo, A., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2014, In: Clinical Chemistry. 60, 5, p. 737-746 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Scavenger receptor AI/II truncation, lung function and COPD: a large population-based study
Thomsen, M., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Dahl, M. & Dahl, M., 2011, In: Journal of Internal Medicine. 269, 3, p. 340-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Scavenger receptor AI/II truncation, lung function and COPD: a large population-based study
Thomsen, M., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Dahl, M., 2011, In: Journal of Internal Medicine. 269, 3, p. 340-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ß2 -adrenergic receptor Thr164IIe polymorphism, blood pressure and ischaemic heart disease in 66¿750 individuals
Thomsen, M., Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Journal of Internal Medicine. 271, 3, p. 305-14 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
β(2) -adrenergic receptor Thr164IIe polymorphism, blood pressure and ischaemic heart disease in 66 750 individuals
Thomsen, M., Dahl, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Journal of Internal Medicine. 271, 3, p. 305-14Research output: Contribution to journal › Journal article › Research › peer-review
- Published
β2-Adrenergic receptor polymorphisms, asthma and COPD: two large population-based studies
Thomsen, M., Nordestgaard, Børge, Sethi, A. A., Tybjærg-Hansen, Anne & Dahl, M., 2012, In: European Respiratory Journal. 39, 3, p. 558-66Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ß2-adrenergic receptor polymorphisms, asthma and COPD: two large population-based studies
Thomsen, M., Nordestgaard, Børge, Sethi, A. A., Tybjærg-Hansen, Anne & Dahl, M., 2012, In: European Respiratory Journal. 39, 3, p. 558-66 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Statistical methods for the time-to-event analysis of individual participant data from multiple epidemiological studies
Thompson, S., Kaptoge, S., White, I., Wood, A., Perry, P., Danesh, J., Jørgensen, T., Emerging Risk Factors Collaboration, E. R. F. C., Tybjærg-Hansen, Anne, Frikke-Schmidt, R. & Nordestgaard, Børge, 1 Oct 2010, In: International Journal of Epidemiology. 39, 5, p. 1345-59 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma Concentrations of Magnesium and Risk of Dementia: A General Population Study of 102 648 Individuals
Thomassen, J. Q., Tolstrup, J. S., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2021, In: Clinical Chemistry. 67, 6, p. 899-911 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma Concentrations of Calcium and Risk of Alzheimer Disease—Observational and Genetic Studies
Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: Clinical Chemistry. 69, 5, p. 525-536 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cascade Screening in Families with Inherited Cardiac Diseases Driven by Cardiologists: Feasibility and Nationwide Outcome in Long QT Syndrome
Theilade, J., Kanters, Jørgen K., Henriksen, F. L., Gilså-Hansen, M., Svendsen, Jesper Hastrup, Eschen, O., Toft, E., Reimers, J. I., Tybjærg-Hansen, Anne, Christiansen, M., Jensen, H. K. & Bundgaard, H., 2013, In: Cardiology. 126, 2, p. 131-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic associations with valvular calcification and aortic stenosis
Thanassoulis, G., Campbell, C. Y., Owens, D. S., Smith, J. G., Smith, A. V., Peloso, G. M., Kerr, K. F., Pechlivanis, S., Budoff, M. J., Harris, T. B., Malhotra, R., O'Brien, K. D., Kamstrup, P. R., Nordestgaard, B. G., Tybjaerg-Hansen, A., Allison, M. A., Aspelund, T., Criqui, M. H., Heckbert, S. R., Hwang, S-J. & 20 others, , 7 Feb 2013, In: New England Journal of Medicine. 368, 6, p. 503-12 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
rs641738C>T near MBOAT7 is associated with liver fat, ALT and fibrosis in NAFLD: A meta-analysis
EU-PNAFLD Investigators, E. I. & GOLD Consortium, G. C., Jan 2021, In: Journal of Hepatology. 74, 1, p. 20-30 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-Genome Sequencing Coupled to Imputation Discovers Genetic Signals for Anthropometric Traits
Tachmazidou, I., Süveges, D., Min, J. L., Ritchie, G. R. S., Steinberg, J., Walter, K., Iotchkova, V., Schwartzentruber, J., Huang, J., Memari, Y., McCarthy, S., Crawford, A. J., Bombieri, C., Cocca, M., Farmaki, A-E., Gaunt, T. R., Jousilahti, P., Kooijman, M. N., Lehne, B., Malerba, G. & 31 others, , 1 Jun 2017, In: American Journal of Human Genetics. 100, 6, p. 865-884 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fatalt forløb ved in vitro-fertilisation
Sørensen, Martin Kryspin, Møller-Sørensen, H., Svane, C., Jensen, C. H., Lange, Kai & Tybjærg-Hansen, Anne, 17 May 2010, In: Ugeskrift for Laeger. 172, 20, p. 1537-8 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ΔF508 heterozygosity and asthma (multiple letters) [1]
Swift, M., Su, Y., Warner, J. O., Lowenfels, A. B., Maisonneuve, P., Palys, B., Schoni, M. H., Redemann, B., Dahl, Morten, Tybjærg-Hansen, Anne, Lange, Peter & Nordestgaard, Børge, 19 Sep 1998, In: The Lancet. 352, 9132, p. 984-987 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: evidence from genetic analysis and randomised trials
Swerdlow, D. I., Preiss, D., Kuchenbaecker, K. B., Holmes, M. V., Engmann, J. E. L., Shah, T., Sofat, R., Stender, S., Johnson, P. C. D., Scott, R. A., Leusink, M., Verweij, N., Sharp, S. J., Guo, Y., Giambartolomei, C., Chung, C., Peasey, A., Amuzu, A., Li, K., Palmen, J. & 113 others, , 24 Jan 2015, In: Lancet. 385, 9965, p. 351-361 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipoprotein(a) Levels at Birth and in Early Childhood: The COMPARE Study
Strandkjær, N., Hansen, M. K., Nielsen, S. T., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Nordestgaard, Børge, Tabor, Ann, Bundgård, Henning, Iversen, Kasper & Kamstrup, P. R., 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 2, p. 324-335 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Context-dependent associations between variation in risk of ischemic heart disease and variation in the 5' promoter region of the apolipoprotein E gene in Danish women
Stengård, J. H., Dyson, G., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Nordestgaard, B. G., Sing, C. F., Stengård, J. H., Dyson, G., Frikke-Schmidt, R., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Sing, C. F., 1 Feb 2010, In: Circulation. Cardiovascular genetics. 3, 1, p. 22-30 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in liver x receptor alpha and risk of ischemic vascular disease in the general population
Stender, S., Frikke-Schmidt, R., Anestis, A., Kardassis, D., Sethi, A. A., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2011, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 31, 12, p. 2990-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variation in Liver X Receptor Alpha and Risk of Ischemic Vascular Disease in the General Population
Stender, Stefan, Frikke-Schmidt, Ruth, Sethi, A. A., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2010, In: Atherosclerosis. Supplement. 11, 2, p. 8-9 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Using human genetics to predict the effects and side-effects of drugs
Stender, S. & Tybjærg-Hansen, Anne, Apr 2016, In: Current Opinion in Lipidology. 27, 2, p. 105-111 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Low-density lipoprotein cholesterol and risk of gallstone disease: A Mendelian randomization study and meta-analyses
Stender, S., Frikke-Schmidt, R., Benn, M., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2013, In: Journal of Hepatology. 58, 1, p. 126-33 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sterol transporter adenosine triphosphate-binding cassette transporter G8, gallstones, and biliary cancer in 62,000 individuals from the general population
Stender, S., Frikke-Schmidt, R., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2011, In: Hepatology. 53, 2, p. 640-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extreme Bilirubin Levels as a Causal Risk Factor for Symptomatic Gallstone Disease
Stender, Stefan, Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2013, In: Annals of Internal Medicine. 173, 13, p. 1222-1228 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci
Stender, S., Kozlitina, J., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Hobbs, H. H. & Cohen, J. C., Jun 2017, In: Nature Genetics. 49, 6, p. 842-847 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationship between genetic variation at PPP1R3B and levels of liver glycogen and triglyceride
Stender, S., Smagris, E., Lauridsen, B. K., Kofoed, Klaus Fuglsang, Nordestgaard, Børge, Tybjærg-Hansen, Anne, Pennacchio, L. A., Dickel, D. E., Cohen, J. C. & Hobbs, H. H., 2018, In: Hepatology. 67, 6, p. 2182-2195 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ABCG5/8 Cholesterol Transporter and Myocardial Infarction Versus Gallstone Disease
Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2014, In: Journal of the American College of Cardiology. 63, 20, p. 2121-2128 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetically elevated bilirubin and risk of ischaemic heart disease: three Mendelian randomization studies and a meta-analysis
Stender, S., Frikke-Schmidt, R., Nordestgaard, Børge, Grande, P. & Tybjærg-Hansen, Anne, 2013, In: The Internet Journal of Internal Medicine. 273, 1, p. 59-68 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to: liver fat content, non-alcoholic fatty liver disease, and ischaemic heart disease
Stender, S. & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 36, p. 3399Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Elevated body mass index as a causal risk factor for symptomatic gallstone disease: A Mendelian randomization study
Stender, Stefan, Nordestgaard, B. G. & Tybjærg-Hansen, Anne, 2013, In: Hepatology. 58, 6, p. 2133–2141Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipoprotein distribution and serum concentrations of 7α-hydroxy-4-cholesten-3-one and bile acids: effects of monogenic disturbances in high-density lipoprotein metabolism
Steiner, C., Holleboom, A. G., Karuna, R., Motazacker, M. M., Kuivenhoven, J. A., Frikke-Schmidt, R., Tybjærg-Hansen, Anne, Rohrer, L., Rentsch, K. M. & von Eckardstein, A., 2012, In: Clinical Science. 122, 8, p. 385-96 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays
Smith, F. A., Howard, P., Shah, S., Eriksson, P., Stender, S., Giambartolomei, C., Folkersen, L. W., Tybjærg-Hansen, Anne, Kumari, M., Palmen, J., Hingorani, A. D., Talmud, P. J. & Humphries, S. E., 2012, In: P L o S Genetics. 8, 8, p. e1002908Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Strengthening the Reporting of Observational Studies in Epidemiology Using Mendelian Randomization: The STROBE-MR Statement
Skrivankova, V. W., Richmond, R. C., Woolf, B. A. R., Yarmolinsky, J., Davies, N. M., Swanson, S. A., Vanderweele, T. J., Higgins, J. P. T., Timpson, N. J., Dimou, N., Langenberg, C., Golub, R. M., Loder, E. W., Gallo, V., Tybjærg-Hansen, Anne, Davey Smith, G., Egger, M. & Richards, J. B., 2021, In: JAMA - Journal of the American Medical Association. 326, 16, p. 1614-1621Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Age-Specific Quantitative Effects of Metabolic Risk Factors on Cardiovascular Diseases and Diabetes: A Pooled Analysis
Singh, G. M., Danaei, G., Farzadfar, F., Stevens, G. A., Woodward, M., Wormser, D., Kaptoge, S., Whitlock, G., Qiao, Q., Lewington, S., Di Angelantonio, E., Vander Hoorn, S., Lawes, C. M. M., Ali, M. K., Mozaffarian, D., Ezzati, M., Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth, Benn, Marianne & Nordestgaard, Børge, Jul 2013, In: P L o S One. 8, 7, p. 1-10 10 p., e65174.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High pre-beta1 HDL concentrations and low lecithin: cholesterol acyltransferase activities are strong positive risk markers for ischemic heart disease and independent of HDL-cholesterol
Sethi, A. A., Sampson, M., Warnick, R., Muniz, N., Vaisman, B., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Remaley, A. T., 1 Jul 2010, In: Clinical Chemistry. 56, 7, p. 1128-37 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
164Ile allele in the beta2-Adrenergic receptor gene is associated with risk of elevated blood pressure in women. The Copenhagen City Heart Study
Sethi, A., Tybjærg-Hansen, A., Jensen, G. B., Nordestgaard, B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2005, In: Pharmacogenetics and Genomics. 15, 9, p. 633-45 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetes mellitus, fasting glucose, and risk of cause-specific death
Seshasai, S. R. K., Kaptoge, S., Thompson, A., Di Angelantonio, E., Gao, P., Sarwar, N., Whincup, P. H., Mukamal, K. J., Gillum, R. F., Holme, I., Njølstad, I., Fletcher, A., Nilsson, C. M. P., Lewington, S., Collins, R., Gudnason, V., Thompson, S. G., Sattar, N., Selvin, E., Hu, F. B. & 7 others, , 2011, In: New England Journal of Medicine. 364, 9, p. 829-41 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variation at PPP1R3B Increases Hepatic CT Attenuation and Interacts With Prandial Status on Plasma Glucose
Seidelin, A., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Stender, S., 2020, In: Journal of Clinical Endrocrinology and Metabolism. 105, 6, p. 1963–1972Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A rare genetic variant in the manganese transporter SLC30A10 and elevated liver enzymes in the general population
Seidelin, A. S., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Yaghootkar, H. & Stender, Stefan, 2022, In: Hepatology International. 16, 3, p. 702-711Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ABC transporter genes and risk of type 2 diabetes: a study of 40,000 individuals from the general population
Schou, J., Tybjærg-Hansen, Anne, Møller, H. J., Nordestgaard, Børge & Frikke-Schmidt, R., 2012, In: Diabetes Care. 35, 12, p. 2600-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 924951
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ABCA7 and risk of dementia and vascular disease in the Danish population
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256
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The UK10K project identifies rare variants in health and disease
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Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease
Research output: Contribution to journal › Journal article › Research › peer-review
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