Maiken Nedergaard

Maiken Nedergaard

Professor

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    101 - 150 out of 165Page size: 50
    1. 2020
    2. Published

      Glymphatic System Impairment in Alzheimer's Disease and Idiopathic Normal Pressure Hydrocephalus

      Reeves, B. C., Karimy, J. K., Kundishora, A. J., Mestre, H., Cerci, H. M., Matouk, C., Alper, S. L., Lundgaard, I., Nedergaard, Maiken & Kahle, K. T., 2020, In: Trends in Molecular Medicine. 26, 3, p. 285-295 11 p.

      Research output: Contribution to journal › Review › Research › peer-review

    3. Astrocytic Endocannabinoids Mediate Hippocampal Transient Heterosynaptic Depression

      Smith, N. A., Bekar, L. K. & Nedergaard, Maiken, 2020, In: Neurochemical Research. 45, 1, p. 100-108 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      A three-dimensional, population-based average of the C57BL/6 mouse brain from DAPI-stained coronal slices

      Stæger, Frederik Filip Vinggaard, Mortensen, K. N., Nielsen, M. S. N., Sigurdsson, B., Kaufmann, L. K., Hirase, Hajime & Nedergaard, Maiken, 2020, In: Scientific Data. 7, 1, 7 p., 235.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Editorial: Sleep and Mood Disorders

      Verkhratsky, A., Nedergaard, Maiken, Steardo, L. & Li, B., 2020, In: Frontiers in Psychiatry. 10, 3 p., 981.

      Research output: Contribution to journal › Editorial › Research › peer-review

    6. Published

      An ocular glymphatic clearance system removes beta-amyloid from the rodent eye

      Wang, X., Lou, N., Eberhardt, A., Yang, Y., Kusk, P., Xu, Q., Forstera, B., Peng, S., Shi, M., Ladron-de-Guevara, A., Delle, Christine, Sigurdsson, B., L R Xavier, Anna , Erturk, A., Libby, R. T., Chen, L., Thrane, A. S. & Nedergaard, Maiken, 2020, In: Science Translational Medicine. 12, 536, eaaw3210.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Perivascular spaces in the brain: anatomy, physiology and pathology

      Wardlaw, J. M., Benveniste, H., Nedergaard, Maiken, Zlokovic, B. V., Mestre, H., Lee, H., Doubal, F. N., Brown, R., Ramirez, J., MacIntosh, B. J., Tannenbaum, A., Ballerini, L., Rungta, R. L., Boido, D., Sweeney, M., Montagne, A., Charpak, S., Joutel, A., Smith, K. J. & Black, S. E., 2020, In: Nature Reviews. Neurology. 16, p. 137-153 17 p.

      Research output: Contribution to journal › Review › Research › peer-review

    8. Published

      Human Glial Progenitor Cells Effectively Remyelinate the Demyelinated Adult Brain

      Windrem, M. S., Schanz, S. J., Zou, L., Chandler-Militello, D., Kuypers, N. J., Nedergaard, Maiken, Lu, Y., Mariani, J. N. & Goldman, Steven Alan, 2020, In: Cell Reports. 31, 7, 23 p., 107658.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. 2019
    10. Published

      Panoptic imaging of transparent mice reveals whole-body neuronal projections and skull-meninges connections

      Cai, R., Pan, C., Ghasemigharagoz, A., Todorov, M. I., Foerstera, B., Zhao, S., Bhatia, H. S., Parra-Damas, A., Mrowka, L., Theodorou, D., Rempfler, M., Xavier, A. L. R., Kress, B. T., Benakis, C., Steinke, H., Liebscher, S., Bechmann, I., Liesz, A., Menze, B., Kerschensteiner, M. & 2 others, Nedergaard, Maiken & Ertuerk, A., 2019, In: Nature Neuroscience. 22, 2, p. 317-327

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      State-Dependent Changes in Brain Glycogen Metabolism

      DiNuzzo, M., Walls, Anne Byriel, Öz, G., Seaquist, E. R., Waagepetersen, Helle S., Bak, Lasse Kristoffer, Nedergaard, Maiken & Schousboe, Arne, 2019, Brain Glycogen Metabolism. DiNuzzo, M. & Schousboe, A. (eds.). Springer, p. 269-309 41 p. (Advances in Neurobiology, Vol. 23).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    12. Published

      Cellular Control of Brain Capillary Blood Flow: In Vivo Imaging Veritas

      Grutzendler, J. & Nedergaard, Maiken, 2019, In: Trends in Neurosciences. 42, 8, p. 528-536 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    13. Published

      Increased glymphatic influx is correlated with high EEG delta power and low heart rate in mice under anesthesia

      Hablitz, L. M., Vinitsky, H. S., Sun, Q., Stæger, Frederik Filip Vinggaard, Sigurdsson, B., Mortensen, K. N., Lilius, T. O. & Nedergaard, Maiken, 2019, In: Science Advances. 5, 2, 9 p., eaav5447.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      EARLY ADDRESS OF POST-TRAUMATIC GLYMPHATIC INSUFFICIENCY REDUCES NEURONAL/GLIAL CELL DEATH AND TISSUE DAMAGES

      Hussain, R., Wang, W. & Nedergaard, Maiken, 2019, In: Journal of Neurotrauma. 36, 13, p. A-101 1 p., B04-05.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    15. Published

      Astrocytes in chronic pain and itch

      Ji, R., Donnelly, C. R. & Nedergaard, Maiken, 2019, In: Nature Reviews Neuroscience. 20, 11, p. 667-685

      Research output: Contribution to journal › Review › Research › peer-review

    16. Published

      Brain Morphometry and Longitudinal Relaxation Time of Spontaneously Hypertensive Rats (SHRs) in Early and Intermediate Stages of Hypertension Investigated by 3D VFA-SPGR MRI

      Koundal, S., Liu, X., Sanggaard, S., Mortensen, K., Wardlaw, J., Nedergaard, Maiken, Benveniste, H. & Lee, H., 2019, In: Neuroscience. 404, p. 14-26

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Genetic haplotype of the glymphatic-associated water channel aquaporin 4 modulates slow waves in human non-rapid eye movement sleep

      Larsen, S. M. U., Landolt, H. P., Berger, W., Nedergaard, Maiken, Knudsen, Gitte Moos & Holst, S. C., 2019, In: European Neuropsychopharmacology. 29, Supplement 6, p. S563-S564 2 p.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    18. Published

      Dexmedetomidine enhances glymphatic brain delivery of intrathecally administered drugs

      Lilius, T. O., Blomqvist, K., Hauglund, Natalie Linea, Liu, G., Stæger, Frederik Filip Vinggaard, Baerentzen, S., Du, T., Ahlstrom, F., Backman, J. T., Kalso, E. A., Rauhala, P. V. & Nedergaard, Maiken, 2019, In: Journal of Controlled Release. 304, p. 29-38 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling

      Liu, Z., Osipovitch, M., Benraiss, A., Huynh, N. P. T., Foti, R., Bates, J., Chandler-Militello, D., Findling, R. L., Tesar, P. J., Nedergaard, Maiken, Windrem, M. S. & Goldman, Steven Alan, 2019, In: Cell Reports. 27, 13, p. 3832-3843, e1-e6

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Adrenergic receptor antagonism induces neuroprotection and facilitates recovery from acute ischemic stroke

      Monai, H., Wang, X., Yahagi, K., Lou, N., Mestre, H., Xu, Q., Abe, Y., Yasui, M., Iwai, Y., Nedergaard, Maiken & Hirase, Hajime, 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 22, p. 11010-11019 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      PDGF-B Is Required for Development of the Glymphatic System

      Munk, A. S., Wang, W., Bèchet, N. B., Eltanahy, A. M., Cheng, A. X., Sigurdsson, B., Benraiss, A., Mäe, M. A., Kress, B. T., Kelley, D. H., Betsholtz, C., Møllgård, Kjeld, Meissner, A., Nedergaard, Maiken & Lundgaard, I., 2019, In: Cell Reports. 26, 11, p. 2955-2969.e3 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      The glymphatic system: reactive gliosis as a negative regulator

      Nedergaard, Maiken, 2019, In: Glia. 67, S1, p. E91 1 p., S26-02.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    23. Published

      Impaired Glymphatic Transport in Spontaneously Hypertensive Rats

      Nygaard Mortensen, K., Sanggaard, S., Mestre, H., Lee, H., Kostrikov, S., L R Xavier, Anna , Gjedde, Albert, Benveniste, H. & Nedergaard, Maiken, 2019, In: The Journal of neuroscience : the official journal of the Society for Neuroscience. 39, 32, p. 6365-6377 23 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Cisterna magna injection in rats to study glymphatic function

      Ramos, M., Burdon Bechet, N., Battistella, R., Pavan, C., L R Xavier, Anna , Nedergaard, Maiken & Lundgaard, I., 2019, Astrocytes: Methods and Protocols. Di Benedetto, B. (ed.). Humana Press, p. 97-104 8 p. (Methods in Molecular Biology, Vol. 1938).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    25. Published

      Cortex-wide Changes in Extracellular Potassium Ions Parallel Brain State Transitions in Awake Behaving Mice

      Rasmussen, R., Nicholas, E., Petersen, Nicolas Caesar, Dietz, Andrea Grostøl, Xu, Q., Sun, Q. & Nedergaard, Maiken, 2019, In: Cell Reports. 28, 5, p. 1182-1194 18 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      SPECT imaging of the glymphatic pathway with In-111-labeled ovalbumin in the rat brain

      Shalgunov, Vladimir, Lilius, T., Sigurosson, B., Baerentzen, S. L., Hauglund, Natalie Linea, Herth, Matthias Manfred, Palner, M. & Nedergaard, Maiken, 2019, In: Journal of Labelled Compounds and Radiopharmaceuticals. 62, Supplement 1, p. S404-S405 2 p.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    27. Published

      In Vivo Imaging of Cerebrospinal Fluid Transport through the Intact Mouse Skull using Fluorescence Macroscopy

      Sweeney, A. M., Pla, V., Du, T., Liu, G., Sun, Q., Peng, S., Plog, B. A., Kress, B. T., Wang, X., Mestre, H. & Nedergaard, Maiken, 2019, In: Journal of Visualized Experiments. 149, 7 p., e59774.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Vascular dysfunction-The disregarded partner of Alzheimer's disease

      Sweeney, M. D., Montagne, A., Sagare, A. P., Nation, D. A., Schneider, L. S., Chui, H. C., Harrington, M. G., Pa, J., Law, M., Wang, D. J. J., Jacobs, R. E., Doubal, F. N., Ramirez, J., Black, S. E., Nedergaard, M., Benveniste, H., Dichgans, M., Iadecola, C., Love, S., Bath, P. M. & 49 others, Markus, H. S., Salman, R. A., Allan, S. M., Quinn, T. J., Kalaria, R. N., Werring, D. J., Carare, R. O., Touyz, R. M., Williams, S. C. R., Moskowitz, M. A., Katusic, Z. S., Lutz, S. E., Lazarov, O., Minshall, R. D., Rehman, J., Davis, T. P., Wellington, C. L., Gonzalez, H. M., Yuan, C., Lockhart, S. N., Hughes, T. M., Chen, C. L. H., Sachdev, P., O'Brien, J. T., Skoog, I., Pantoni, L., Gustafson, D. R., Biessels, G. J., Wallin, A., Smith, E. E., Mok, V., Wong, A., Passmore, P., Barkof, F., Muller, M., Breteler, M. M. B., Roman, G. C., Hamel, E., Seshadri, S., Gottesman, R. F., van Buchem, M. A., Arvanitakis, Z., Schneider, J. A., Drewes, L. R., Hachinski, V., Finch, C. E., Toga, A. W., Wardlaw, J. M. & Zlokovic, B. V., 2019, In: Alzheimers & Dementia. 15, 1, p. 158-167

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Astrocytic connexin 43 potentiates myelin injury in ischemic white matter disease

      Wang, M., Qin, C., Luo, X., Wang, J., Wang, X., Xie, M., Hu, J., Cao, J., Hu, T., Goldman, Steven Alan, Nedergaard, Maiken & Wang, W., 2019, In: Theranostics. 9, 15, p. 4474-4493 20 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    30. Published

      The Ocular Glymphatic Clearance System

      Wang, X., Lou, N., Eberhardt, A., Jørgensen, P. K., Xu, Q., Foerstera, B., Peng, S., Yang, Y., Shi, M., L R Xavier, Anna , Ertürk, A., Libby, R. T., Lu, C., Thrane, A. & Nedergaard, Maiken, 30 Dec 2019, bioRxiv, 23 p.

      Research output: Working paper › Preprint › Research

    31. 2018
    32. Published

      Cerebral Metabolic Changes During Sleep

      Aalling, Nadia, Nedergaard, Maiken & DiNuzzo, M., 1 Sep 2018, In: Current Neurology and Neuroscience Reports. 18, 9, 17 p., 57.

      Research output: Contribution to journal › Review › Research › peer-review

    33. Published

      Understanding the role of the perivascular space in cerebral small vessel disease

      Brown, R., Benveniste, H., Black, S. E., Charpak, S., Dichgans, M., Joutel, A., Nedergaard, Maiken, Smith, K. J., Zlokovic, B. V. & Wardlaw, J. M., 2018, In: Cardiovascular Research. 114, 11, p. 1462-1473 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      AMELIORATION OF GLYMPHATIC PATHWAY IS CRITICAL FOR LONG TERM RECOVERY FROM TRAUMATIC BRAIN INJURY

      Hussain, R., Wang, W., Cheetham-West, A. O., Sun, Q. & Nedergaard, Maiken, 2018, p. A204. 1 p.

      Research output: Contribution to conference › Conference abstract for conference › Research

    35. Published

      Altered physiological brain variation in drug-resistant epilepsy

      Kananen, J., Tuovinen, T., Ansakorpi, H., Rytky, S., Helakari, H., Huotari, N., Raitamaa, L., Raatikainen, V., Rasila, A., Borchardt, V., Korhonen, V., LeVan, P., Nedergaard, Maiken & Kiviniemi, V., 2018, In: Brain and Behavior. 8, 9, p. 1-17 17 p., e01090.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Quantitative Gd-DOTA uptake from cerebrospinal fluid into rat brain using 3D VFA-SPGR at 9.4T

      Lee, H., Mortensen, K., Sanggaard, S., Koch, P., Brunner, H., Quistorff, B., Nedergaard, Maiken & Benveniste, H., 2018, In: Magnetic Resonance in Medicine. 79, 3, p. 1568-1578 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      Beneficial effects of low alcohol exposure, but adverse effects of high alcohol intake on glymphatic function

      Lundgaard, I., Wang, W., Eberhardt, A., Vinitsky, H. S., Reeves, B. C., Peng, S., Lou, N., Hussain, R. & Nedergaard, Maiken, 2018, In: Scientific Reports. 8, 1, 16 p., 2246.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      Aquaporin-4-dependent glymphatic solute transport in the rodent brain

      Mestre, H., Hablitz, L. M., Xavier, A. L. R., Feng, W., Zou, W., Pu, T., Monai, H., Murlidharan, G., Rivera, R. M. C., Simon, M. J., Pike, M. M., Pla, V., Du, T., Kress, B. T., Wang, X., Plog, B. A., Thrane, A. S., Lundgaard, I., Abe, Y., Yasui, M. & 6 others, Thomas, J. H., Xiao, M., Hirase, Hajime, Asokan, A., Iliff, J. J. & Nedergaard, Maiken, 2018, In: eLife. 7, 31 p., :e40070.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Flow of cerebrospinal fluid is driven by arterial pulsations and is reduced in hypertension

      Mestre, H., Tithof, J., Du, T., Song, W., Peng, W., Sweeney, A. M., Olveda, G., Thomas, J. H., Nedergaard, Maiken & Kelley, D. H., 2018, In: Nature Communications. 9, 1, 9 p., 4878.

      Research output: Contribution to journal › Journal article › Research › peer-review

    40. Published

      The glymphatic pathway in neurological disorders

      Rasmussen, Martin Kaag, Mestre, H. & Nedergaard, Maiken, 2018, In: The Lancet Neurology. 17, 11, p. 1016-1024 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    41. Published

      Brain Segmentation in Rodent MR-Images Using Convolutional Neural Networks

      Sigurdsson, B., Darkner, Sune, Sommer, Stefan Horst, Mortensen, K. N., Sanggaard, S., Kostrikov, S. & Nedergaard, Maiken, 2018.

      Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

    42. Published

      Physiology of astroglia

      Verkhratsky, A. & Nedergaard, Maiken, 2018, In: Physiological Reviews. 98, 1, p. 239-389 151 p.

      Research output: Contribution to journal › Review › Research › peer-review

    43. Published

      Cannula Implantation into the Cisterna Magna of Rodents

      L R Xavier, Anna , Hauglund, Natalie Linea, Holstein-Rønsbo, Stephanie, Li, Q., Sanggaard, S., Lou, N., Lundgaard, I. & Nedergaard, Maiken, 2018, In: Journal of Visualized Experiments. 135, 6 p., e57378.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      Voluntary running enhances glymphatic influx in awake behaving, young mice

      Holstein-Rønsbo, Stephanie, Petersen, Nicolas Caesar & Nedergaard, Maiken, 2018, In: Neuroscience Letters. 662, p. 253-258 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. 2017
    46. Published

      Cerebrospinal fluid clearance in Alzheimer disease measured with dynamic PET

      De Leon, M. J., Li, Y., Okamura, N., Tsui, W. H., Saint-Louis, L. A., Glodzik, L., Osorio, R. S., Fortea, J., Butler, T., Pirraglia, E., Fossati, S., Kim, H. J., Carare, R. O., Nedergaard, Maiken, Benveniste, H. & Rusinek, H., 2017, In: Journal of Nuclear Medicine. 58, 9, p. 1471-1476 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Brain energetics during the sleep-wake cycle

      DiNuzzo, M. & Nedergaard, Maiken, Dec 2017, In: Current Opinion in Neurobiology. 47, p. 65-72 8 p.

      Research output: Contribution to journal › Review › Research › peer-review

    48. Published

      Impairment of the glymphatic system after diabetes

      Jiang, Q., Zhang, L., Ding, G., Davoodi-Bojd, E., Li, Q., Li, L., Sadry, N., Nedergaard, Maiken, Chopp, M. & Zhang, Z., 1 Apr 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 4, p. 1326-1337 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    49. Published

      Does Global Astrocytic Calcium Signaling Participate in Awake Brain State Transitions and Neuronal Circuit Function?

      Kjærby, Celia, Rasmussen, R., Andersen, Mie & Nedergaard, Maiken, Jun 2017, In: Neurochemical Research. 42, 6, p. 1810-1822 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Understanding the functions and relationships of the glymphatic system and meningeal lymphatics

      Louveau, A., Plog, B. A., Antila, S., Alitalo, K., Nedergaard, Maiken & Kipnis, J., 1 Sep 2017, In: The Journal of Clinical Investigation. 127, 9, p. 3210-3219 10 p.

      Research output: Contribution to journal › Review › Research › peer-review

    51. Published

      Glymphatic clearance controls state-dependent changes in brain lactate concentration

      Lundgaard, I., Lu, M. L., Yang, E., Peng, W., Mestre, H., Hitomi, E., Deane, R. & Nedergaard, Maiken, Jun 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 6, p. 2112-2124 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      Perivascular spaces, glymphatic dysfunction, and small vessel disease

      Mestre, H., Kostrikov, S., Mehta, R. I. & Nedergaard, Maiken, 1 Sep 2017, In: Clinical Science. 131, 17, p. 2257-2274 18 p.

      Research output: Contribution to journal › Review › Research › peer-review

    53. Published

      Do Evolutionary Changes in Astrocytes Contribute to the Computational Power of the Hominid Brain?

      Oberheim Bush, N. A. & Nedergaard, Maiken, Sep 2017, In: Neurochemical Research. 42, 9, p. 2577-2587 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. Published

      SOX9 is an astrocyte-specific nuclear marker in the adult brain outside the neurogenic regions

      Sun, W., Cornwell, A., Li, J., Peng, S., Joana Osorio, M., Aalling, Nadia, Wang, S., Benraiss, A., Lou, N., Goldman, Steven Alan & Nedergaard, Maiken, 2017, In: Journal of Neuroscience. 37, 17, p. 4493-4507 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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