Hans K Hasselbalch

Hans K Hasselbalch

Clinical Professor

Member of:

  • Internal Medicine: Haematology


  1. 2017
  2. Published

    Epigenetic changes in myelofibrosis: Distinct methylation changes in the myeloid compartments and in cases with ASXL1 mutations

    Myrtue Nielsen, H., Andersen, Christen Bertel L, Westman, M., Sommer Kristensen, L., Asmar, F., Arvid Kruse, T., Thomassen, M., Stauffer Larsen, T., Skov, V., Lotte Hansen, L., Weis Bjerrum, O., Hasselbalch, Hans Carl, Punj, V. & Grønbæk, Kirsten, 2017, In: Scientific Reports. 7, 11 p., 6774.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Non-invasive imaging of retinal blood flow in myeloproliferative neoplasms

    Willerslev, A., Hansen, M. M., Klefter, O. N., Bjerrum, O. W., Hasselbalch, Hans Carl, Clemmensen, S. N., Larsen, Michael & Munch, I. C., Mar 2017, In: Acta Ophthalmologica. 95, 2, p. 146–152

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2016
  5. Published

    A new internet-based tool for reporting and analysing patient-reported outcomes and the feasibility of repeated data collection from patients with myeloproliferative neoplasms

    Brochmann, N., Zwisler, A., Kjerholt, M., Flachs, E. M., Hasselbalch, Hans Carl & Andersen, Christen Bertel L, 2016, In: Quality of Life Research. 25, 4, p. 835-846 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Chronic inflammation and autoimmunity as risk factors for the development of chronic myelomonocytic leukemia?

    Elbæk, M. V., Sørensen, A. L. & Hasselbalch, Hans Carl, 2 Aug 2016, In: Leukemia and Lymphoma. 57, 8, p. 1793-1799 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Interferon-α induces marked alterations in circulating regulatory T cells, NK cell subsets, and dendritic cells in patients with JAK2V617F-positive essential thrombocythemia and polycythemia vera

    Riley, C. H., Brimnes, M. K., Hansen, M., Jensen, M. K., Hasselbalch, Hans Carl, Kjaer, L., Straten, P. T. & Svane, Inge Marie, 2016, In: European Journal of Haematology. 97, 1, p. 83-92 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Optimal therapy for polycythemia vera and essential thrombocythemia: Preferred use of interferon therapy based on phase 2 trials

    Silver, R. T. & Hasselbalch, Hans Carl, 2016, In: Hematology. 21, 7, p. 387-391 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Antecedent cardiovascular disease and autoimmunity in Philadelphia-negative chronic myeloproliferative neoplasms

    Sørensen, A. L. & Hasselbalch, Hans Carl, 1 Feb 2016, In: Leukemia Research. 41, p. 27-35 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. 2015
  11. Published

    Association of the blood eosinophil count with hematological malignancies and mortality

    Andersen, Christen Bertel L, Siersma, Volkert Dirk, Hasselbalch, Hans Carl, Vestergaard, H., Mesa, R., Felding, P., Olivarius, Niels de Fine & Bjerrum, O. W., Mar 2015, In: American Journal of Hematology. 90, 3, p. 225-229 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Whole-exome sequencing and genome-wide methylation analyses identify novel disease associated mutations and methylation patterns in idiopathic hypereosinophilic syndrome

    Andersen, Christen Bertel L, Nielsen, H. M., Sommer Kristensen, L., Helbo, A. S., Vikeså, J., Jønson, L., Nielsen, Finn Cilius, Hasselbalch, Hans Carl, Bjerrum, O. W., Punj, V. & Grønbæk, Kirsten, 2015, In: OncoTarget. 6, 38, p. 40588-97 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    WHO classification 2008 of myeloproliferative neoplasms: a workshop learning effect - the Danish experience

    Madelung, A. B., Bondo, H., Stamp, I., Løvgreen, P., Nielsen, S. L., Falensteen, A., Knudsen, H., Svendsen, K. D., Lange, Theis, Ralfkiaer, E., Nielsen, K., Hasselbalch, Hans Carl & Thiele, J., Sep 2015, In: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. 123, 9, p. 787-92 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. 2014
  15. Published

    Circulating YKL-40 in myelofibrosis a potential novel biomarker of disease activity and the inflammatory state

    Bjørn, M. E., Andersen, Christen Bertel L, Jensen, M. K. & Hasselbalch, Hans Carl, 2014, In: European Journal of Haematology. 93, 3, p. 224-228 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. 2013
  17. Published

    Chronic inflammation as a promotor of mutagenesis in essential thrombocythemia, polycythemia vera and myelofibrosis. A human inflammation model for cancer development?

    Hasselbalch, Hans Carl, Feb 2013, In: Leukemia Research. 37, 2, p. 214-20 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    The role of cytokines in the initiation and progression of myelofibrosis

    Hasselbalch, Hans Carl, Apr 2013, In: Cytokine & Growth Factor Reviews. 24, 2, p. 133-45 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Interferon and the treatment of polycythemia vera, essential thrombocythemia and myelofibrosis

    Silver, R. T., Kiladjian, J. & Hasselbalch, Hans Carl, Feb 2013, In: Expert Review of Hematology. 6, 1, p. 49-58 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2012
  21. Published

    Lack of somatic mutations in the catalytic domains of CREBBP and EP300 genes implies a role for histone deacetylase inhibition in myeloproliferative neoplasms

    Andersen, Christen Bertel L, Grønbæk, Kirsten & Hasselbalch, Hans Carl, 1 Apr 2012, In: Leukemia Research. 36, 4, p. 485-487 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Somatic mutations of the CREBBP and EP300 genes affect response to histone deacetylase inhibition in malignant DLBCL clones

    Andersen, Christen Bertel L, Asmar, F., Klausen, T., Hasselbalch, Hans Carl & Grønbæk, K., 2012, In: Leukemia Research Reports. 2, 1, p. 1-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Thrombopoietin-receptor agonists in haematological disorders: The Danish experience

    Gudbrandsdottir, S., Hasselbalch, Hans Carl & Frederiksen, H., 1 Sep 2012, In: Platelets. 23, 6, p. 423-429 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published
  25. Published

    A highly sensitive quantitative real-time pcr assay for determination of mutant jak2 exon 12 allele burden

    Kjær, L., Riley, C. H., Westman, M., Høgdall, Estrid Vilma Solyom, Bjerrum, O. W. & Hasselbalch, Hans Carl, 5 Mar 2012, In: PLOS ONE. 7, 3

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    A novel immunohistochemical sequential multi-labelling and erasing technique enables epitope characterization of bone marrow pericytes in primary myelofibrosis

    Madelung, A., Bzorek, M., Bondo, H., Zetterberg, E., Bjerrum, O. W., Hasselbalch, Hans Carl, Scheding, S. & Ralfkiaer, E., 2012, In: Histopathology. 60: 554 – 660.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Gene expression profiling with principal component analysis depicts the biological continuum from essential thrombocythemia over polycythemia vera to myelofibrosis

    Skov, V., Thomassen, M., Kruse, T. A., Riley, C. H., Jensen, M. K., Bjerrum, O. W., Hasselbalch, Hans Carl & Larsen, T. S., 1 Sep 2012, In: Experimental Hematology. 40, 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Molecular profiling of peripheral blood cells from patients with polycythemia vera and related neoplasms: Identification of deregulated genes of significance for inflammation and immune surveillance

    Skov, V., Thomassen, M., Kruse, T. A., Larsen, T. S., Riley, C. H., Jensen, M. S. K., Bjerrum, O. W. & Hasselbalch, Hans Carl, 1 Nov 2012, In: Leukemia Research. 36, 11, p. 1387-1392 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2011
  30. Published

    Philadelphia-negative classical myeloproliferative neoplasms: critical concepts and management recommendations from European leukemiaNet

    Barbui, T., Barosi, G., Birgegard, G., Cervantes, F., Finazzi, G., Griesshammer, M., Harrison, C., Hasselbalch, H. C., Hehlmann, R., Hoffman, R., Kiladjian, J-J., Kröger, N., Mesa, R., McMullin, M. F., Pardanani, A., Passamonti, F., Vannucchi, A. M., Reiter, A., Silver, R. T., Verstovsek, S. & 1 others, Tefferi, A., 20 Feb 2011, In: Journal of Clinical Oncology. 29, 6, p. 761-770 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Chronic myeloproliferative neoplasms and subsequent cancer risk: A Danish population-based cohort study

    Frederiksen, H., Farkas, D. K., Christiansen, C. F., Sørensen, H. T. & Hasselbalch, Hans Carl, 15 Dec 2011, In: Blood. 118, 25, p. 6515-6520 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Fibroproliferative activity in patients with immune thrombocytopenia (ITP) treated with thrombopoietic agents

    Ghanima, W., Bussel, J. B., Junker, P., Hasselbalch, Hans Carl, Gudbrandsdottir, S., Boiocchi, L., Geyer, J. T., Orazi, A. & Feng, X., 1 Oct 2011, In: British Journal of Haematology. 155, 2, p. 248-255 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    A new era for IFN-α in the treatment of Philadelphia-negative chronic myeloproliferative neoplasms

    Hasselbalch, Hans Carl, 1 Dec 2011, In: Expert Review of Hematology. 4, 6, p. 637-655 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Interferon alfa in the treatment of philadelphia-negative chronic myeloproliferative neoplasms

    Hasselbalch, Hans Carl, Kiladjian, J. & Silver, R. T., 20 Jun 2011, In: Journal of Clinical Oncology. 29, 18

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Interferon alpha2 in the treatment of hematological malignancies. status and perspectives

    Hasselbalch, Hans Carl, 1 Jan 2011, In: Current Drug Targets. 12, 3, p. 387-391 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Interferon-alpha in the treatment of Philadelphia-negative chronic myeloproliferative neoplasms. Status and perspectives

    Hasselbalch, Hans Carl, Larsen, T. S., Riley, C. H., Jensen, M. K. & Kiladjian, J., 1 Jan 2011, In: Current Drug Targets. 12, 3, p. 392-419 28 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Increase in circulating CD4CD25Foxp3 T cells in patients with Philadelphia-negative chronic myeloproliferative neoplasms during treatment with IFN-α

    Riley, C. H., Morten Krogh, J., Brimnes, M. K., Straten, P. T., Svane, Inge Marie, Hasselbalch, Hans Carl & Bjerrum, O. W., 25 Aug 2011, In: Blood. 118, 8, p. 2170-2173 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    High expression of carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 6 and 8 in primary myelofibrosis

    Hasselbalch, Hans Carl, Skov, V., Larsen, T. S., Thomassen, M., Riley, C. H., Jensen, M. K., Bjerrum, O. W. & Kruse, T. A., 2011, In: Leukemia Research. 35, 10, p. 1330-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. 2008
  40. Published

    Does primary myelofibrosis involve a defective stem cell niche? From concept to evidence

    Lataillade, J. J., Pierre-Louis, O., Uzan, G., Jasmin, C., Martyre, M. C., Bousse-Kerdiles, M. C. L. & Hasselbalch, Hans Carl, 2008, In: Blood. 112, 8, p. 3026-3035 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. 1996
  42. Published

    Sonographic measurement of the thymus in infants

    Hasselbalch, Hans Carl, Nielsen, Michael Bachmann, Jeppesen, Dorthe Lisbeth, Pedersen, J. F. & Karkov, J., 1996, In: European Radiology. 6, 5, p. 700-703 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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