Ulla M. Wewer
Professor
Globe Administration
Øster Voldgade 5-7
1350 København K
- 2004
- Published
ADAM 12 cleaves extracellular matrix proteins and correlates with cancer status and stage
Roy, R., Wewer, Ulla M., Zurakowski, D., Pories, S. E. & Moses, M. A., 3 Dec 2004, In: Journal of Biological Chemistry. 279, 49, p. 51323-30 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of ADAM12 cell-surface expression by protein kinase C epsilon.
Sundberg, C., Thodeti, C. K., Kveiborg, Marie, Larsson, C., Parker, P., Albrechtsen, Reidar & Wewer, Ulla M., 2004, In: Journal of Biological Chemistry. 279, 49, p. 51601-11 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
The new frontier in muscular dystrophy: Booster genes.
Engvall, E. & Wewer, Ulla M., 2003, In: The FASEB Journal. 17, p. 1579-1584Research output: Contribution to journal › Journal article › Research
- Published
The new frontier in muscular dystrophy research: booster genes
Engvall, E. & Wewer, Ulla M., 1 Sep 2003, In: F A S E B Journal. 17, 12, p. 1579-84 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Laminin alpha2 deficiency and muscular dystrophy; genotype-phenotype correlation in mutant mice
Guo, L. T., Zhang, X. U., Kuang, W., Xu, H., Liu, L. A., Vilquin, J., Miyagoe-Suzuki, Y., Takeda, S., Ruegg, M. A., Wewer, Ulla M. & Engvall, E., 1 Mar 2003, In: Neuromuscular Disorders. 13, 3, p. 207-15 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Laminin afra2 deficiency and muscular dystrophy: genotype-phenotype correlation in mutant mice.
Guo, L. T., Zhang, X. U., Kang, W., Xu, H., Liu, L. A., Miyagoe-Suzuki, Y., Takeda, S., Ruegg, M., Wewer, Ulla M. & Engvall, E., 2003, In: Neuromuscular Disorders. 13, p. 207-215Research output: Contribution to journal › Journal article › Research
- Published
ADAM12 induces actin cytoskeleton and extracellular matrix reorganization during early adipocyte differentiation by regulating beta1 integrin function.
Kawaguchi, N., Sundberg, C., Kveiborg, Marie, Moghadaszadeh, B., Asmar, M., Dietrich, N., Thodeti, C. K., Nielsen, F. C., Möller, P., Mercurio, A. M., Albrechtsen, Reidar & Wewer, Ulla M., 2003, In: Journal of Cell Science. 116, Pt 19, p. 3893-904 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12: a novel first-trimester maternal serum marker for Down syndrome.
Laigaard, J., Sørensen, T., Fröhlich, C., Pedersen, B. N., Christiansen, M., Schiøtt, K., Uldbjerg, N., Albrechtsen, Reidar, Clausen, H. V., Ottesen, B. & Wewer, Ulla M., 2003, In: Prenatal Diagnosis. 23, 13, p. 1086-91 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12 in human liver cancers: TGF-beta-regulated expression in stellate cells is associated with matrix remodeling
Le Pabic, H., Bonnier, D., Wewer, Ulla M., Coutand, A., Musso, O., Baffet, G., Clément, B. & Théret, N., 1 May 2003, In: Hepatology. 37, 5, p. 1056-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alfa7 integrin, utrophin, and associated glycoproteins.
Moghadas Zadeh, S. B., Albrechtsen, Reidar, Guo, L. T., Zaik, M., Kawaguchi, N., Borup, R. H., Kronqvist, P. E., Schröder, H. D., Davies, K. E., Voit, T., Nielsen, F. C., Engvall, E. & Wewer, Ulla M., 2003, In: Human Molecular Genetics. 12, p. 2467-2479Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alpha 7 integrin, utrophin and associated glycoproteins
Moghadaszadeh, B., Albrechtsen, Reidar, Guo, L. T., Zaik, M., Kawaguchi, N., Borup, R. H., Kronqvist, P., Schroder, H. D., Davies, K. E., Voit, T., Nielsen, Finn Cilius, Engvall, E. & Wewer, Ulla M., 1 Oct 2003, In: Human Molecular Genetics. 12, 19, p. 2467-79 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
114th ENMC International Workshop on Congenital Muscular Dystrophy (CMD) 17-19 January 2003, Naarden, The Netherlands: (8th Workshop of the International Consortium on CMD; 3rd Workshop of the MYO-CLUSTER project GENRE)
Muntoni, F., Valero de Bernabe, B., Bittner, R., Blake, D., van Bokhoven, H., Brockington, M., Brown, S., Bushby, K., Campbell, K. P., Fiszman, M., Gruenewald, S., Merlini, L., Quijano-Roy, S., Romero, N., Sabatelli, P., Sewry, C. A., Straub, V., Talim, B., Topaloglu, H., Voit, T. & 4 others, , 1 Sep 2003, In: Neuromuscular Disorders. 13, 7-8, p. 579-88 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An endoplasmic reticulum glycoprotein with an early development expression pattern.
Petit, N., Lescure, A., Rederstorff, M., Krol, A., Moghadas Zadeh, S. B., Wewer, Ulla M. & Guicheney, P., 2003, In: Human Molecular Genetics. 12, p. 1045-1053Research output: Contribution to journal › Journal article › Research
- Published
Selenoprotein N: an endoplasmic reticulum glycoprotein with an early developmental expression pattern
Petit, N., Lescure, A., Rederstorff, M., Krol, A., Moghadaszadeh, B., Wewer, Ulla M. & Guicheney, P., 1 May 2003, In: Human Molecular Genetics. 12, 9, p. 1045-53 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2002
- Published
ADAM 12 protease induces adipogenesis in transgenic mice.
Kawaguchi, N., Xu, X., Tajima, R., Kronqvist, P., Sundberg, C., Loechel, F., Albrechtsen, Reidar & Wewer, Ulla M., 2002, In: American Journal of Pathology. 160, 5, p. 1895-903 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12 alleviates the skeletal muscle pathology in mdx dystrophic mice
Kronqvist, P., Kawaguchi, N., Albrechtsen, Reidar, Xu, X., Schrøder, H. D., Moghadaszadeh, B., Nielsen, Finn Cilius, Frohlich, C., Engvall, E. & Wewer, Ulla M., 1 Nov 2002, In: American Journal of Pathology. 161, 5, p. 1535-40 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM 12 alleviates the skeletal muscle 0pathology in mdx dystrophic mice
Kronqvist, P. E., Kawaguchi, N., Albrechtsen, Reidar, Xu, X., Schrøder, H. D., Moghadas Zadeh, S. B., Nielsen, F. C., Frohlich, L. C., Engvall, E. & Wewer, Ulla M., 2002, In: American Journal of Pathology. 161, p. 1535-1540Research output: Contribution to journal › Journal article › Research › peer-review
- Published
98th ENMC International Workshop on Congenital Muscular Dystrophy (CMD), 7th Workshop of the International Consortium on CMD, 2nd Workshop of the MYO CLUSTER project GENRE. 26-28th October, 2001, Naarden, The Netherlands
Muntoni, F., Bertini, E., Bönnemann, C., Brockington, M., Brown, S., Bushby, K., Fiszman, M., Körner, C., Mercuri, E., Merlini, L., Hewitt, J., Quijano-Roy, S., Romero, N., Squarzoni, S., Sewry, C. A., Straub, V., Topaloglu, H., Haliloglu, G., Voit, T., Wewer, U. & 1 others, , 1 Nov 2002, In: Neuromuscular Disorders. 12, 9, p. 889-96 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
98th ENMC International Workshop on congenital Muscular Dystrophy (CMD)
Muntoni, F., Bertine, E., Bonnemann, C., Brockington, M., Bushby, K., Fiszman, M., Korner, C., Mercuri, E., Merlini, L., Hewitt, J., Quijano-Roy, S., Romero, N., Squarzoni, S., Sewry, C. A., Straub, V., Hopaloglu, H., Haliloglu, G., Voit, T., Wewer, Ulla M. & Guicheney, P., 2002, In: Neuromuscular Disorders. 12, p. 889-896Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM12/syndecan-4 signaling promotes beta 1 integrin-dependent cell spreading through protein kinase Calpha and RhoA.
Thodeti, C. K., Albrechtsen, Reidar, Grauslund, M., Asmar, M., Larsson, C., Takada, Y., Mercurio, A. M., Couchman, John Robert & Wewer, Ulla M., 2002, In: Journal of Biological Chemistry. 278, 11, p. 9576-84 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tetranectin
Wewer, Ulla M. & Albrechtsen, Reidar, 2002, In: Wiley Encyclopedia of Molecular Medicine. 5, p. 3117-3118Research output: Contribution to journal › Journal article › Research
- 2001
- Published
Regulation of laminin beta2 chain gene expression in human cancer cell lines.
Durkin, M. E., Nielsen, F. C., Loechel, F., Albrechtsen, Reidar & Wewer, Ulla M., 2001, In: European Journal of Biochemistry. 268, 13, p. 3797-806 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mice with a targeted deletion of the tetranectin gene exhibit a spinal deformity.
Iba, K., Durkin, M. E., Johnsen, L., Hunziker, E., Damgaard-Pedersen, K., Zhang, H., Engvall, E., Albrechtsen, Reidar & Wewer, Ulla M., 2001, In: Molecular and Cellular Biology. 21, 22, p. 7817-25 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of ADAM 12 protease by copper
Loechel, F. & Wewer, Ulla M., 2001, In: FEBS Letters. 506, 1, p. 65-68 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
E2F repression by C/EBPalpha is required for adipogenesis and granulopoiesis in vivo.
Porse, Bo Torben, Pedersen TA, Xu, X., Lindberg, B., Wewer, Ulla M., Friis-Hansen, L. & Nerlov, C., 2001, In: Cell. 107, 2, p. 247-58 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tetranectin in slow intra- and extrafusal chicken muscle fibers.
Xu, X., Gilpin, B., Iba, K., Maier, A., Engvall, E., Albrechtsen, Reidar & Wewer, Ulla M., 2001, In: Journal of Muscle Research and Cell Motility. 22, 2, p. 121-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2000
- Published
Binding of ADAM12, a marker for skeletal muscle regeneration, to the muscle-specific actin-binding protein, alfa-actinin-2, is required for myoblast fusion.
Galliano, H., Frygelius, J., Polgren, A. & Wewer, Ulla M., 2000, In: Journal of Biological Chemistry. 275, p. 13933-13999Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Binding of ADAM12, a marker of skeletal muscle regeneration, to the muscle-specific actin-binding protein, alpha -actinin-2, is required for myoblast fusion
Galliano, M. F., Huet, C., Frygelius, J., Polgren, A., Wewer, Ulla M. & Engvall, E., 5 May 2000, In: Journal of Biological Chemistry. 275, 18, p. 13933-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trafficking of human ADAM 12-L: retention in the trans-Golgi network.
Hougaard, S., Loechel, F., Xu, X., Tajima, R., Albrechtsen, Reidar & Wewer, Ulla M., 2000, In: Biochemical and Biophysical Research Communications. 275, 2, p. 261-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The cysteine-rich domain of human ADAM 12 supports cell adhesion through syndecans and triggers signaling events that lead to beta1 integrin-dependent cell spreading.
Iba, K., Albrechtsen, Reidar, Gilpin, B., Frohlich, C., Loechel, F., Zolkiewska, A., Ishiguro, K., Kojima, T., Liu, W., Langford, J. K., Sanderson, R. D., Brakebusch, Cord Herbert, Fässler, R. & Wewer, Ulla M., 2000, In: Journal of Cell Biology. 149, 5, p. 1143-56 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM 12-S cleaves IGFBP-3 and IGFBP-5 and is inhibited by TIMP-3.
Loechel, F., Fox, J. W., Murphy, G., Albrechtsen, Reidar & Wewer, Ulla M., 2000, In: Biochemical and Biophysical Research Communications. 278, 3, p. 511-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
H19 RNA binds four molecules of insulin-like growth factor II mRNA-binding protein
Runge, S., Nielsen, Finn Cilius, Nielsen, J., Andersen, J. L., Wewer, Ulla M. & Christiansen, Jan, 2000, In: Journal of Biological Chemistry. 275, 38, p. 29562-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAM 12, a disintegrin metalloprotease, interacts with insulin-like growth factor-binding protein-3
Shi, Z., Xu, W., Loechel, F., Wewer, Ulla M. & Murphy, L., 2000, In: Journal of Biological Chemistry. 275, 24, p. 18574-18580Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Celle-matrix-interaktioner ved cancer
Wewer, Ulla M., 2000, In: Ugeskrift for læger. 162, 36, p. 4783-5 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1999
- Published
Characterization of the human laminin beta2 chain locus (LAMB2): linkage to a gene containing a nonprocessed, transcribed LAMB2-like pseudogene (LAMB2L) and to the gene encoding glutaminyl tRNA synthetase (QARS).
Durkin, M. E., Jäger, A. C., Khurana, T. S., Nielsen, F. C., Albrechtsen, Reidar & Wewer, Ulla M., 1999, In: Cytogenetic and Genome Research. 84, 3-4, p. 173-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cysteine-rich domain of human ADAM 12 (meltrin alpha) supports tumor cell adhesion.
Iba, K., Albrechtsen, Reidar, Gilpin, B. J., Loechel, F. & Wewer, Ulla M., 1999, In: American Journal of Pathology. 154, 5, p. 1489-501 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of human ADAM 12 protease by the prodomain. Evidence for a functional cysteine switch.
Loechel, F., Overgaard, M. T., Oxvig, C., Albrechtsen, Reidar & Wewer, Ulla M., 1999, In: Journal of Biological Chemistry. 274, 19, p. 13427-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development
Nielsen, J., Christiansen, Jan, Lykke-Andersen, J., Johnsen, A. H., Wewer, Ulla M. & Nielsen, Finn Cilius, 1999, In: Molecular and Cellular Biology. 19, 2, p. 1262-1270 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Laminin alpha2 chain-deficient congenital muscular dystrophy: variable epitope expression in severe and mild cases
Cohn, R. D., Herrmann, R., Sorokin, L., Wewer, Ulla M. & Voit, T., 1 Jul 1998, In: Neurology. 51, 1, p. 94-100 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Laminin alpha2 chain-deficient muscular dystrophy: variable epitope expression in severe and mild cases
Cohn, R. D., Herrmann, R. J., Sorokin, L., Wewer, Ulla M. & Voit, T., 1998, In: Neurology. 51, p. 94-100Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evaluation of Lama5 as a candidate for the mouse ragged (Ra) mutation.
Durkin, M. E., Albrechtsen, Reidar, Chambers, D. M., Abbott, C. M. & Wewer, Ulla M., 1998, In: Biochemical and Biophysical Research Communications. 250, 1, p. 125-30 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel, secreted form of human ADAM 12 (meltrin alpha) provokes myogenesis in vivo.
Gilpin, B. J., Loechel, F., Mattei, M. G., Engvall, E., Albrechtsen, Reidar & Wewer, Ulla M., 1998, In: Journal of Biological Chemistry. 273, 1, p. 157-66 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Merosin-deficient congenital muscular dystrophy. Partial genetic correction in two mouse models
Kuang, W., Xu, H., Vachon, P. H., Liu, L., Loechel, F., Wewer, Ulla M. & Engvall, E., 1998, In: Journal of Clinical Investigation. 102, 4, p. 844-52 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic correction of merosin deficiency in the dy2J mouse model of congenital muscular dystrophy. Partial genetic correction in two models
Kuang, W., Xu, H., Vachon, P. H., Liu, L., Loechel, F., Wewer, Ulla M. & Engvall, E., 1998, In: Journal of Clinical Investigation. 102, p. 844-852Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human ADAM 12 (meltrin alpha) is an active metalloprotease.
Loechel, F., Gilpin, B. J., Engvall, E., Albrechtsen, Reidar & Wewer, Ulla M., 1998, In: Journal of Biological Chemistry. 273, 27, p. 16993-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Congenital myasthenic syndromes in two kinships with end-plate acetylcholine receptor and utrophin deficiency
Sieb, J. P., Dörfler, P., Tzartos, S., Wewer, Ulla M., Rüegg, M. A., Meyer, D., Baumann, I., Lindemuth, R., Jakschik, J. & Ries, F., 1 Jan 1998, In: Neurology. 50, 1, p. 54-61 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Congenital myastenic syndromes in two kinships with endplate acetylcholine receptor and utropin deficiency
Sieb, J. P., Dörfler, P., Tzartos, S., Wewer, Ulla M., Rüegg, M. A., Meyer, D., Baumann, I. & Lindemuth, R., 1998, In: Neurology. 50, p. 54-61Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tetranectin is a novel marker for myogenesis during embryonic development, muscle regeneration, and muscle cell differentiation in vitro.
Wewer, Ulla M., Iba, K., Durkin, M. E., Nielsen, F. C., Loechel, F., Gilpin, B. J., Kuang, W., Engvall, E. & Albrechtsen, Reidar, 1998, In: Developmental Biology. 200, 2, p. 247-59 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
Changes of laminin beta 2 chain expression in congenital muscular dystrophy
Cohn, R. D., Herrmann, R., Wewer, Ulla M. & Voit, T., 1 Sep 1997, In: Neuromuscular Disorders. 7, 6-7, p. 373-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in laminin ß2 chain expression in congenital muscular dystrophy
Cohn, R. D., Herremann, R., Wewer, Ulla M. & Voit, T., 1997, In: Neuromuscular Disorders. 7, p. 373-374Research output: Contribution to journal › Journal article › Research › peer-review
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The Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell Behaviour
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