Erika Villanueva
Postdoc
Molecular and Cellular Pharmacology
Jagtvej 160, Building: 22-3-333
2100 København
Denmark
Molecular and Cellular Pharmacology
Jagtvej 160
2100 København Ø
- 2021
- Published
Neuronal TNFα, not α-syn, underlies PDD-like disease progression in IFNβ-KO mice
Villanueva, Erika Bianca, Tresse-Gommeaux, Emilie, Liu, Yawei, Duarte, J. N., Jimenez-Duran, G., Ejlerskov, P., Kretz, O., Loreth, D., Goldmann, T., Prinz, M. & Issazadeh-Navikas, Shohreh, 2021, In: Annals of Neurology. 90, 5, p. 789-807Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
ANTIBODIES INHIBIT CELL TO CELL TRANSMISSION OF MUTANT HTT
Bartl, S., Oueslati, A., Southwell, A. L., Parth, M., Salhat, N., Siddu, A., Burkert, M., Pankevych, H., David, L., Villanueva, Erika Bianca, Xie, Y., Dal Cengio, L., Ko, S., Hayden, M. R., Cicchetti, F. & Smrzka, O. W., Sep 2018, p. A91-A91.Research output: Contribution to conference › Poster › Research
HACE1 is essential for astrocyte mitochondrial function and influences Huntington disease phenotypes in vivo
Ehrnhoefer, D. E., Southwell, A. L., Sivasubramanian, M., Qiu, X., Villanueva, Erika Bianca, Xie, Y., Waltl, S., Anderson, L., Fazeli, A., Casal, L., Felczak, B., Tsang, M. & Hayden, M. R., 15 Jan 2018, In: Human Molecular Genetics. 27, 2, p. 239-253 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
Huntingtin suppression restores cognitive function in a mouse model of Huntington's disease
Southwell, A. L., Kordasiewicz, H. B., Langbehn, D., Skotte, Niels Henning, Parsons, M. P., Villanueva, Erika Bianca, Caron, N. S., Østergaard, M. E., Anderson, L. M., Xie, Y., Cengio, L. D., Findlay-Black, H., Doty, C. N., Fitsimmons, B., Swayze, E. E., Seth, P. P., Raymond, L. A., Frank Bennett, C. & Hayden, M. R., 2018, In: Science Translational Medicine. 10, 461, p. 1-12 eaar3959.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
A novel humanized mouse model of Huntington disease for preclinical development of therapeutics targeting mutant huntingtin alleles
Southwell, A. L., Skotte, N. H., Villanueva, E. B., Østergaard, M. E., Gu, X., Kordasiewicz, H. B., Kay, C., Cheung, D., Xie, Y., Waltl, S., Dal Cengio, L., Findlay-Black, H., Doty, C. N., Petoukhov, E., Iworima, D., Slama, R., Ooi, J., Pouladi, M. A., Yang, X. W., Swayze, E. E. & 2 others, , 15 Mar 2017, In: Human Molecular Genetics. 26, 6, p. 1115-1132 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
An enhanced Q175 knock-in mouse model of Huntington disease with higher mutant huntingtin levels and accelerated disease phenotypes
Southwell, A. L., Smith-Dijak, A., Kay, C., Sepers, M., Villanueva, Erika Bianca, Parsons, M. P., Xie, Y., Anderson, L., Felczak, B., Waltl, S., Ko, S., Cheung, D., Dal Cengio, L., Slama, R., Petoukhov, E., Raymond, L. A. & Hayden, M. R., 1 Sep 2016, In: Human Molecular Genetics. 25, 17, p. 3654-3675 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
Anti-semaphorin 4D immunotherapy ameliorates neuropathology and some cognitive impairment in the YAC128 mouse model of Huntington disease
Southwell, A. L., Franciosi, S., Villanueva, Erika Bianca, Xie, Y., Winter, L. A., Veeraraghavan, J., Jonason, A., Felczak, B., Zhang, W., Kovalik, V., Waltl, S., Hall, G., Pouladi, M. A., Smith, E. S., Bowers, W. J., Zauderer, M. & Hayden, M. R., Apr 2015, In: Neurobiology of Disease. 76, p. 46-56 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Ultrasensitive measurement of huntingtin protein in cerebrospinal fluid demonstrates increase with Huntington disease stage and decrease following brain huntingtin suppression
Southwell, A. L., Smith, S. E. P., Davis, T. R., Caron, N. S., Villanueva, Erika Bianca, Xie, Y., Collins, J. A., Ye, M. L., Sturrock, A., Leavitt, B. R., Schrum, A. G. & Hayden, M. R., 15 Jul 2015, In: Scientific Reports. 5, p. 12166Research output: Contribution to journal › Journal article › Research › peer-review
Therapeutic Potential of Cannabinoids in the Treatment of Neuroinflammation Associated with Parkinson's Disease
Villanueva, Erika Bianca, Little, J. P. & Klegeris, A., 30 Nov 2015, Recent Advances in Medicinal Chemistry. Atta-ur-Rahman, Choudhary, M. I. & Perry, G. (eds.). Bentham Science Publishers, p. 59-75Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2014
Mitochondrial transcription factor A (Tfam) is a pro-inflammatory extracellular signaling molecule recognized by brain microglia
Little, J. P., Simtchouk, S., Schindler, S. M., Villanueva, Erika Bianca, Gill, N. E., Walker, D. G., Wolthers, K. R. & Klegeris, A., May 2014, In: Molecular and Cellular Neuroscience. 60, p. 88-96 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
In vivo evaluation of candidate allele-specific mutant huntingtin gene silencing antisense oligonucleotides
Southwell, A. L., Skotte, Niels Henning, Kordasiewicz, H. B., Østergaard, M. E., Watt, A. T., Carroll, J. B., Doty, C. N., Villanueva, Erika Bianca, Petoukhov, E., Vaid, K., Xie, Y., Freier, S. M., Swayze, E. E., Seth, P. P., Bennett, C. F. & Hayden, M. R., Dec 2014, In: Molecular Therapy. 22, 12, p. 2093-106 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
A fully humanized transgenic mouse model of Huntington disease
Southwell, A. L., Warby, S. C., Carroll, J. B., Doty, C. N., Skotte, Niels Henning, Zhang, W., Villanueva, Erika Bianca, Kovalik, V., Xie, Y., Pouladi, M. A., Collins, J. A., Yang, X. W., Franciosi, S. & Hayden, M. R., 1 Jan 2013, In: Human Molecular Genetics. 22, 1, p. 18-34 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
Rational design of antisense oligonucleotides targeting single nucleotide polymorphisms for potent and allele selective suppression of mutant Huntingtin in the CNS
Østergaard, M. E., Southwell, A. L., Kordasiewicz, H., Watt, A. T., Skotte, Niels Henning, Doty, C. N., Vaid, K., Villanueva, Erika Bianca, Swayze, E. E., Bennett, C. F., Hayden, M. R. & Seth, P. P., Nov 2013, In: Nucleic Acids Research. 41, 21, p. 9634-50 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
Secreted phospholipase A2 group IIA is a neurotoxin released by stimulated human glial cells
Villanueva, Erika Bianca, Little, J. P., Lambeau, G. & Klegeris, A., 2012, In: Molecular and Cellular Neuroscience.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
Moderate increase in temperature may exacerbate neuroinflammatory processes in the brain: human cell culture studies
Bahniwal, M., Villanueva, Erika Bianca & Klegeris, A., Apr 2011, In: Journal of Neuroimmunology. 233, 1-2, p. 65-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Cultured adult porcine astrocytes and microglia express functional interferon-γ receptors and exhibit toxicity towards SH-SY5Y cells
Ionescu, V. A., Villanueva, Erika Bianca, Hashioka, S., Bahniwal, M. & Klegeris, A., 28 Feb 2011, In: Brain Research Bulletin. 84, 3, p. 244-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
Therapeutic potential of cannabinoids in the treatment of neuroinflammation associated with Parkinson's disease
Little, J. P., Villanueva, Erika Bianca & Klegeris, A., Jun 2011, In: Mini reviews in medicinal chemistry. 11, 7, p. 582-90 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Therapeutic Potential of Cannabinoids in the Treatment of Neuroinflammation Associated with Parkinsons Disease
Little, J. P., Villanueva, Erika Bianca & Klegeris, A., 1 Jun 2011, In: Mini-Reviews in Medicinal Chemistry.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
Synthesis and biological evaluation of novel pyrazole compounds
Youssef, A. M., Neeland, E. G., Villanueva, Erika Bianca, White, M. S., El-Ashmawy, I. M., Patrick, B., Klegeris, A. & Abd-El-Aziz, A. S., 1 Aug 2010, In: Bioorganic & Medicinal Chemistry. 18, 15, p. 5685-96 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
Synthesis and biological evaluation of novel pyrazolyl-2,4-thiazolidinediones as anti-inflammatory and neuroprotective agents
Youssef, A. M., White, M. S., Villanueva, Erika Bianca, El-Ashmawy, I. M. & Klegeris, A., 1 Mar 2010, In: Bioorganic & Medicinal Chemistry. 18, 5, p. 2019-28 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 157553808
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Neuronal TNFα, not α-syn, underlies PDD-like disease progression in IFNβ-KO mice
Research output: Contribution to journal › Journal article › Research › peer-review
Published