Indra John Heckenbach
Guest Researcher
Molecular Aging Program
Blegdamsvej 3
2200 København N.
- Published
A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function
Boutoual, R., Jo, H., Heckenbach, Indra John, Tiwari, R., Kasler, H., Lerner, C. A., Shah, S., Schilling, B., Calvanese, V., Rardin, M. J., Scheibye-Knudsen, Morten & Verdin, E., 2022, In: Scientific Reports. 12, 14804.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CD38 regulates ovarian function and fecundity via NAD+ metabolism
Perrone, R., Ashok Kumaar, P. V., Haky, L., Hahn, C., Riley, R., Balough, J., Zaza, G., Soygur, B., Hung, K., Prado, L., Kasler, H. G., Tiwari, R., Matsui, H., Hormazabal, G. V., Heckenbach, Indra John, Scheibye-Knudsen, Morten, Duncan, F. E. & Verdin, E., 2023, In: iScience. 26, 10, 27 p., 107949.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Deep Learning to Characterize Cellular Senescence in Aging and Age-related Diseases
Heckenbach, Indra John, 4 Apr 2023, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
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Histone malonylation is regulated by SIRT5 and KAT2A
Zhang, R., Bons, J., Scheidemantle, G., Liu, X., Bielska, O., Carrico, C., Rose, J., Heckenbach, Indra John, Scheibye-Knudsen, Morten, Schilling, B. & Verdin, E., 2023, In: iScience. 26, 3, 106193.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health
Lee, P. J., Benz, C. C., Blood, P., Börner, K., Campisi, J., Chen, F., Daldrup-Link, H., De Jager, P., Ding, L., Duncan, F. E., Eickelberg, O., Fan, R., Finkel, T., Furman, D., Garovic, V., Gehlenborg, N., Glass, C., Heckenbach, I., Joseph, Z. B., Katiyar, P. & 48 others, , 2022, In: Nature Aging. 2, 12, p. 1090-1100 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nuclear morphology is a deep learning biomarker of cellular senescence
Heckenbach, Indra John, Mkrtchyan, Garik, Ben Ezra, Michael, Bakula, Daniela Janina, Madsen, Jakob Sture, Nielsen, M. H., Oró, D., Osborne, Brenna, Covarrubias, A. J., Idda, M. L., Gorospe, M., Mortensen, Laust Hvas, Verdin, E., Westendorp, Rudi GJ & Scheibye-Knudsen, Morten, 2022, In: Nature Aging. 2, 8, p. 742-755 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of lamin B receptor levels by miR-340-5p disrupts chromatin, promotes cell senescence and enhances senolysis
Herman, A. B., Anerillas, C., Harris, S. C., Munk, R., Martindale, J. L., Yang, X., Mazan-Mamczarz, K., Zhang, Y., Heckenbach, Indra John, Scheibye-Knudsen, Morten, De, S., Sen, P., Abdelmohsen, K. & Gorospe, M., 2021, In: Nucleic Acids Research. 49, 13, p. 7389-7405 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
Covarrubias, A. J., Kale, A., Perrone, R., Lopez-Dominguez, J. A., Pisco, A. O., Kasler, H. G., Schmidt, M. S., Heckenbach, I., Kwok, R., Wiley, C. D., Wong, H. S., Gibbs, E., Iyer, S. S., Basisty, N., Wu, Q., Kim, I. J., Silva, E., Vitangcol, K., Shin, K. O., Lee, Y. M. & 11 others, , 2020, In: Nature Metabolism. 2, 11, p. 1265-1283 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tracking the dynamics of cellular senescence
Heckenbach, Indra John & Scheibye-Knudsen, Morten, 2023, In: Aging. 15, 9, p. 3219-3220 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
ID: 203399293
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Nuclear morphology is a deep learning biomarker of cellular senescence
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
22
downloads
A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
17
downloads
CD38 regulates ovarian function and fecundity via NAD+ metabolism
Research output: Contribution to journal › Journal article › Research › peer-review
Published