Jens Bukh

Jens Bukh

Professor

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    ORCID: 0000-0002-7815-4806

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    1. Published

      Immunity against the GBV-B hepatitis virus in tamarins can prevent productive infection following rechallenge and is long-lived

      Bukh, Jens, Engle, R. E., Govindarajan, S. & Purcell, R. H., 2008, In: Journal of Medical Virology. 80, 1, p. 87-94 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Immunoglobulin with High-Titer In Vitro Cross-Neutralizing Hepatitis C Virus Antibodies Passively Protects Chimpanzees from Homologous, but Not Heterologous, Challenge

      Bukh, Jens, Engle, R. E., Faulk, K., Wang, R. Y., Farci, P., Alter, H. J. & Purcell, R. H., Sep 2015, In: Journal of Virology. 89, 17, p. 9128-9132 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      In vitro efficacy of artemisinin-based treatments against SARS-CoV-2

      Zhou, Y., Gilmore, K., Ramirez Almeida, Santseharay, Settels, E., Gammeltoft, Karen Anbro, Pham, Long, Fahnøe, Ulrik, Feng, S., Offersgaard, Anna Falden, Trimpert, J., Bukh, Jens, Osterrieder, K., Gottwein, Judith Margarete & Seeberger, P. H., 2021, In: Scientific Reports. 11, 14571.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      In vitro neutralization assay using cultured hepatitis C virus

      Prentø, Jannick & Bukh, Jens, 2019, Hepatitis C Virus Protocols. Humana Press, p. 433-439 7 p. (Methods in Molecular Biology, Vol. 1911).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    5. Published

      In vivo evaluation of the cross-genotype neutralizing activity of polyclonal antibodies against hepatitis C virus

      Meuleman, P., Bukh, Jens, Verhoye, L., Farhoudi, A., Vanwolleghem, T., Wang, R. Y., Desombere, I., Alter, H., Purcell, R. H. & Leroux-Roels, G., 2011, In: Hepatology. 53, 3, p. 755-62

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      In vivo study of the HC-TN strain of hepatitis C virus recovered from a patient with fulminant hepatitis: RNA transcripts of a molecular clone (pHC-TN) are infectious in chimpanzees but not in Huh7.5 cells

      Sakai, A., Takikawa, S., Thimme, R., Meunier, J. C., Spangenberg, H. C., Govindarajan, S., Farci, P., Emerson, S. U., Chisari, F. V., Purcell, R. H. & Bukh, Jens, 2007, In: Journal of Virology. 81, 13, p. 7208-7219 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Inactivated genotype 1a, 2a and 3a HCV vaccine candidates induced broadly neutralising antibodies in mice

      Alzua, G. P., Pihl, A. F., Offersgaard, Anna Falden, Duarte Hernandez, Carlos Rene, Duan, Z., Feng, S., Fahnøe, Ulrik, Sølund, C., Weis, Nina, Law, M., Prentø, Jannick, Christensen, Jan Pravsgaard, Bukh, Jens & Gottwein, Judith Margarete, 2023, In: Gut. 72, 3, p. 560-572

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Inactivated whole hepatitis C virus vaccine employing a licensed adjuvant elicits cross-genotype neutralizing antibodies in mice

      Pihl, A. F., Feng, S., Offersgaard, Anna Falden, Alzua, G. P., Augestad, Elias Honerød, Mathiesen, C. K., Jensen, T. B., Krarup, H., Law, M., Prentø, Jannick, Christensen, Jan Pravsgaard, Bukh, Jens & Gottwein, Judith Margarete, 2022, In: Journal of Hepatology. 76, 5, p. 1051-1061

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Infectious genotype 1a, 1b, 2a, 2b, 3a, 5a, 6a and 7a hepatitis C virus lacking the hypervariable region 1 (HVR1): Patent #: 8,846,891

      Prentø, Jannick, Gottwein, Judith Margarete, Scheel, T. K. H., Bukh, Jens & Jensen, T. B., 30 Sep 2014, IPC No. C07H 21/04 (20060101); C07H 21/02 (20060101), Patent No. WO2010/022727, 4 Mar 2010, Priority date 7 Aug 2009, Priority No. PCT/DK2009/050197

      Research output: Patent

    10. Published

      Infectious hepatitis C viruses of genotype 3A and 4A and uses thereof: Patent #: 8,946,398

      Gottwein, Judith Margarete, Scheel, T. K. H., Purcell, R. E. & Bukh, Jens, 3 Feb 2015, IPC No. C07H 21/04 (20060101); C07H 21/02 (20060101), Patent No. WO2011/038737, 26 Jul 2012, Priority date 16 Sep 2010, Priority No. PCT/DK2010/050236

      Research output: Patent

    11. Published

      Inferior cure rate in pilot study of 4-week glecaprevir/pibrentasvir treatment with or without ribavirin of chronic hepatitis C

      Madsen, L. W., Christensen, P. B., Fahnøe, Ulrik, Pedersen, M. S., Bukh, Jens & Øvrehus, A., 2021, In: Liver International. 41, 11, p. 2601-2610

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Insights into the unique characteristics of hepatitis C virus genotype 3 revealed by development of a robust sub-genomic DBN3a replicon

      Ward, J. C., Bowyer, S., Chen, S., Fernandes Campos, G. R., Ramirez Almeida, Santseharay, Bukh, Jens & Harris, M., 2020, In: The Journal of general virology. 101, 11, p. 1182-1190 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Interleukin-28B polymorphisms are associated with hepatitis C virus clearance and viral load in a HIV-1-infected cohort

      Clausen, L. N., Weis, Nina, Astvad, K., Schønning, Kristian, Fenger, M., Krarup, H., Bukh, Jens & Benfield, Thomas, 2011, In: Journal of Viral Hepatitis. 18, 4, p. e66-e74 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Intragenotypic JFH1 based recombinant hepatitis C virus produces high levels of infectious particles but causes increased cell death.

      Mateu, G., Donis, R. O., Wakita, T., Bukh, Jens & Grakoui, A., 2008, In: Virology. 376, 2, p. 397-407 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Isolation and characterization of broadly neutralizing human monoclonal antibodies to the e1 glycoprotein of hepatitis C virus

      Meunier, J., Russell, R. S., Goossens, V., Priem, S., Walther, H., Depla, E., Union, A., Faulk, K. N., Bukh, Jens, Emerson, S. U. & Purcell, R. E., 2008, In: Journal of Virology. 82, 2, p. 966-73 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Lipid Droplets Accumulation during Hepatitis C Virus Infection in Cell-Culture Varies among Genotype 1-3 Strains and Does Not Correlate with Virus Replication

      Galli, Andrea, Ramirez Almeida, Santseharay & Bukh, Jens, 2021, In: Viruses. 13, 3, 389.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      MONOCISTRONIC HEPATITIS C REPORTER VIRUS RECOMBINANTS OF ALL MAJOR GENOTYPES EXPRESSING ENHANCED GREEN FLUORESCENT PROTEIN TAGGED NS5A PROTEIN

      Gottwein, Judith Margarete, Lademann, J. B., Scheel, Troels Kasper Høyer, Jensen, T. B., Prentø, Jannick & Bukh, Jens, 2009, In: Journal of Hepatology. 50, p. S33-S33

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Mechanisms and Consequences of Genetic Variation in Hepatitis C Virus (HCV)

      Galli, Andrea & Bukh, Jens, 2023, Viral Fitness and Evolution: Population Dynamics and Adaptive Mechanisms. Springer, p. 237-264 28 p. (Current Topics in Microbiology and Immunology, Vol. 439).

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    19. Published

      MicroRNA-122 antagonism against hepatitis C virus genotypes 1-6 and reduced efficacy by host RNA insertion or mutations in the HCV 5' UTR

      Li, Y., Gottwein, J., Scheel, Troels Kasper Høyer, Jensen, T. B. & Bukh, Jens, 2011, In: Proceedings of the National Academy of Sciences of the United States of America. 108, 12, p. 4991-4996

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Molecular Determinants of Mouse Adaptation of Rat Hepacivirus

      Wolfisberg, R., Holmbeck, Kenn, Billerbeck, E., Thorselius, Caroline Eva, Batista, M. N., Fahnøe, Ulrik, Lundsgaard, Emma Alberte, Kennedy, Matthew James, Nielsen, L., Rice, C. M., Bukh, Jens & Scheel, Troels Kasper Høyer, 2023, In: Journal of Virology. 97, 4, 17 p., e0181222.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Molecular and epidemiological profiles of hepatitis C virus genotype 4 in Denmark

      Eriksen, M. B., Jørgensen, L. B., Krarup, H., Laursen, A. L., Christensen, P. B., Møller, A., Schlichting, P., Kuiken, C., Bukh, Jens, Weis, N. & DANHEP Group, D. G., 2010, In: Journal of Medical Virology. 82, 11, p. 1869-1877 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Molecular evolution of GB virus B hepatitis virus during acute resolving and persistent infections in experimentally infected tamarins

      Takikawa, S., Engle, R. E., Faulk, K. N., Emerson, S. U., Purcell, R. H. & Bukh, Jens, 2010, In: Journal of General Virology. 91, Pt 3, p. 727-33 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Monitoring of hepatitis C virus quasispecies in chronic infection by matrix-assisted laser desorption ionization-time of flight mass spectrometry mutation detection

      Yea, C., Bukh, Jens, Ayers, M., Roberts, E., Krajden, M. & Tellier, R., 2007, In: Journal of Clinical Microbiology. 45, 3, p. 1053-1057 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Mouse models of acute and chronic hepacivirus infection

      Billerbeck, E., Wolfisberg, R., Fahnøe, Ulrik, Xiao, J. W., Quirk, C., Luna, J. M., Cullen, J. M., Hartlage, A. S., Chiriboga, L., Ghoshal, K., Lipkin, W. I., Bukh, Jens, Scheel, Troels Kasper Høyer, Kapoor, A. & Rice, C. M., 2017, In: Science. 357, 6347, p. 204-208 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Mutational analysis of the hepatitis C virus E1 glycoprotein in retroviral pseudoparticles and cell-culture-derived H77/JFH1 chimeric infectious virus particles

      Russell, R. S., Kawaguchi, K., Meunier, J., Takikawa, S., Faulk, K., Bukh, Jens, Purcell, R. H. & Emerson, S. U., 2009, In: Journal of Viral Hepatitis. 16, 9, p. 621-32 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 12437