Ruth Loos
Professor
Loos Group
Blegdamsvej 3B, Mærsk Tårnet, 7. sal
2200 København N.
Markers for cardiovascular disease in monozygotic twins discordant for the use of third-generation oral contraceptives
Loos, Ruth, Verhaeghe, J., De Zegher, F., Beunen, G., Derom, C., Fagard, R., Mathieu, C. & Vlietinck, R., Jul 2003, In: Journal of Human Hypertension. 17, 7, p. 481-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Melanocortin-4 receptor gene and physical activity in the Québec Family Study
Loos, Ruth, Rankinen, T., Tremblay, A., Pérusse, L., Chagnon, Y. & Bouchard, C., Apr 2005, In: International journal of obesity (2005). 29, 4, p. 420-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Mendelian randomisation studies of type 2 diabetes: future prospects
Sandhu, M. S., Debenham, S. L., Barroso, I. & Loos, Ruth, Feb 2008, In: Diabetologia. 51, 2, p. 211-3 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mendelian randomization supports bidirectional causality between telomere length and clonal hematopoiesis of indeterminate potential
Nakao, T., Bick, A. G., Taub, M. A., Zekavat, S. M., Uddin, M. M., Niroula, A., Carty, C. L., Lane, J., Honigberg, M. C., Weinstock, J. S., Pampana, A., Gibson, C. J., Griffin, G. K., Clarke, S. L., Bhattacharya, R., Assimes, T. L., Emery, L. S., Stilp, A. M., Wong, Q., Broome, J. & 32 others, , 2022, In: Science Advances. 8, 14, eabl6579.Research output: Contribution to journal › Journal article › Research › peer-review
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Meta-analysis uncovers genome-wide significant variants for rapid kidney function decline
Gorski, M., Jung, B., Li, Y., Matias-Garcia, P. R., Wuttke, M., Coassin, S., Thio, C. H. L., Kleber, M. E., Winkler, T. W., Wanner, V., Chai, J-F., Chu, A. Y., Cocca, M., Feitosa, M. F., Ghasemi, S., Hoppmann, A., Horn, K., Li, M., Nutile, T., Scholz, M. & 31 others, , 2021, In: Kidney International. 99, 4, p. 926-939Research output: Contribution to journal › Journal article › Research › peer-review
Modelling bivariate ordinal responses smoothly with examples from ophthalmology and genetics
Bustami, R., Lesaffre, E., Molenberghs, G., Loos, Ruth, Danckaerts, M. & Vlietinck, R., 30 Jun 2001, In: Statistics in Medicine. 20, 12, p. 1825-42 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mosaic chromosomal alterations in blood across ancestries using whole-genome sequencing
Jakubek, Y. A., Zhou, Y., Stilp, A., Bacon, J., Wong, J. W., Ozcan, Z., Arnett, D., Barnes, K., Bis, J. C., Boerwinkle, E., Brody, J. A., Carson, A. P., Chasman, D. I., Chen, J., Cho, M., Conomos, M. P., Cox, N., Doyle, M. F., Fornage, M., Guo, X. & 31 others, , 2023, In: Nature Genetics. 55, 11, p. 1912-1919 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multi-ancestry GWAS of the electrocardiographic PR interval identifies 202 loci underlying cardiac conduction
Ntalla, I., Weng, L. C., Cartwright, J. H., Hall, A. W., Sveinbjornsson, G., Tucker, N. R., Choi, S. H., Chaffin, M. D., Roselli, C., Barnes, M. R., Mifsud, B., Warren, H. R., Hayward, C., Marten, J., Cranley, J. J., Concas, M. P., Gasparini, P., Boutin, T., Kolcic, I., Polasek, O. & 167 others, , 1 Dec 2020, In: Nature Communications. 11, 1, 2542.Research output: Contribution to journal › Journal article › Research › peer-review
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Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
Mahajan, A., Spracklen, C. N., Zhang, W., Ng, M. C. Y., Petty, L. E., Kitajima, H., Yu, G. Z., Rüeger, S., Speidel, L., Kim, Y. J., Horikoshi, M., Mercader, J. M., Taliun, D., Moon, S., Kwak, S-H., Robertson, N. R., Rayner, N. W., Loh, M., Kim, B-J., Chiou, J. & 31 others, , 2022, In: Nature Genetics. 54, 5, p. 560-572 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multi-ancestry genome-wide association study of major depression aids locus discovery, fine mapping, gene prioritization and causal inference
Meng, X., Navoly, G., Giannakopoulou, O., Levey, D. F., Koller, D., Pathak, G. A., Koen, N., Lin, K., Adams, M. J., Rentería, M. E., Feng, Y., Gaziano, J. M., Stein, D. J., Zar, H. J., Campbell, M. L., van Heel, D. A., Trivedi, B., Finer, S., McQuillin, A., Bass, N. & 58 others, , 2024, In: Nature Genetics. 56, 2, p. 222–233Research output: Contribution to journal › Journal article › Research › peer-review
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Multi-ancestry genome-wide gene-smoking interaction study of 387,272 individuals identifies new loci associated with serum lipids
Bentley, A. R., Sung, Y. J., Brown, M. R., Winkler, T. W., Kraja, A. T., Ntalla, I., Schwander, K., Chasman, D. I., Lim, E., Deng, X., Guo, X., Liu, J., Lu, Y., Cheng, C-Y., Sim, X., Vojinovic, D., Huffman, J. E., Musani, S. K., Li, C., Feitosa, M. F. & 32 others, , Apr 2019, In: Nature Genetics. 51, 4, p. 636-648 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Multi-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications
VA Million Veteran Program, V. M. V. P., 2023, medRxiv, 39 p.Research output: Working paper › Preprint
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Multi-ancestry study of blood lipid levels identifies four loci interacting with physical activity
Kilpeläinen, T. O., Bentley, A. R., Noordam, R., Sung, Y. J., Schwander, K., Winkler, T. W., Jakupović, H., Chasman, D. I., Manning, A., Ntalla, I., Aschard, H., Brown, M. R., de las Fuentes, L., Franceschini, N., Guo, X., Vojinovic, D., Aslibekyan, S., Feitosa, M. F., Kho, M., Musani, S. K. & 32 others, , 2019, In: Nature Communications. 10, 11 p., 376.Research output: Contribution to journal › Journal article › Research › peer-review
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Multi-ethnic genome-wide association study for atrial fibrillation
Roselli, C., Chaffin, M. D., Weng, L-C., Aeschbacher, S., Ahlberg, G., Albert, C. M., Almgren, P., Alonso, A., Anderson, C. D., Aragam, K. G., Arking, D. E., Barnard, J., Bartz, T. M., Benjamin, E. J., Bihlmeyer, N. A., Bis, J. C., Bloom, H. L., Boerwinkle, E., Bottinger, E. B., Brody, J. A. & 34 others, , Sep 2018, In: Nature Genetics. 50, 9, p. 1225-1233Research output: Contribution to journal › Journal article › Research › peer-review
Multi-population genome-wide association study implicates immune and non-immune factors in pediatric steroid-sensitive nephrotic syndrome
Barry, A., McNulty, M. T., Jia, X., Gupta, Y., Debiec, H., Luo, Y., Nagano, C., Horinouchi, T., Jung, S., Colucci, M., Ahram, D. F., Mitrotti, A., Sinha, A., Teeninga, N., Jin, G., Shril, S., Caridi, G., Bodria, M., Lim, T. Y., Westland, R. & 50 others, , 2023, In: Nature Communications. 14, 1, 2481.Research output: Contribution to journal › Journal article › Research › peer-review
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Multiancestry Genome-Wide Association Study of Aortic Stenosis Identifies Multiple Novel Loci in the Million Veteran Program
Small, A. M., Peloso, G. M., Linefsky, J., Aragam, J., Galloway, A., Tanukonda, V., Wang, L. C., Yu, Z., Sunitha Selvaraj, M., Farber-Eger, E. H., Baker, M. T., Setia-Verma, S., Lee, S. S. K., Preuss, M., Ritchie, M. D., Damrauer, S. M., Rader, D. J., Wells, Q. S., Loos, R., Lubitz, S. A. & 5 others, , 2023, In: Circulation. 147, 12, p. 942-955 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
Neonatal neuronal overexpression of glycogen synthase kinase-3 beta reduces brain size in transgenic mice
Spittaels, K., Van den Haute, C., Van Dorpe, J., Terwel, D., Vandezande, K., Lasrado, R., Bruynseels, K., Irizarry, M., Verhoye, M., Van Lint, J., Vandenheede, J. R., Ashton, D., Mercken, M., Loos, Ruth, Hyman, B., Van der Linden, A., Geerts, H. & Van Leuven, F., 2002, In: Neuroscience. 113, 4, p. 797-808 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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New Blood Pressure-Associated Loci Identified in Meta-Analyses of 475000 Individuals
Kraja, A. T., Cook, J. P., Warren, H. R., Surendran, P., Liu, C., Evangelou, E., Manning, A. K., Grarup, N., Drenos, F., Sim, X., Smith, A. V., Amin, N., Blakemore, A. I. F., Bork-Jensen, J., Brandslund, I., Farmaki, A-E., Fava, C., Ferreira, T., Herzig, K-H., Giri, A. & 122 others, , Oct 2017, In: Circulation: Cardiovascular Genetics. 10, 5Research output: Contribution to journal › Journal article › Research › peer-review
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New insights in the mechanisms of weight-loss maintenance: Summary from a Pennington symposium
Flanagan, E. W., Spann, R., Berry, S. E., Berthoud, H. R., Broyles, S., Foster, G. D., Krakoff, J., Loos, Ruth, Lowe, M. R., Ostendorf, D. M., Powell-Wiley, T. M., Redman, L. M., Rosenbaum, M., Schauer, P. R., Seeley, R. J., Swinburn, B. A., Hall, K. & Ravussin, E., 2023, In: Obesity. 31, 12, p. 2895-2908Research output: Contribution to journal › Journal article › Research › peer-review
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New loci for body fat percentage reveal link between adiposity and cardiometabolic disease risk
Lu, Y., Day, F. R., Gustafsson, S., Buchkovich, M. L., Na, J., Bataille, V., Cousminer, D. L., Dastani, Z., Drong, A. W., Esko, T., Evans, D. M., Falchi, M., Feitosa, M. F., Ferreira, T., Hedman, Å. K., Haring, R., Hysi, P. G., Iles, M. M., Justice, A. E., Kanoni, S. & 239 others, , 1 Feb 2016, In: Nature Communications. 7, p. 1-15 15 p., 10495.Research output: Contribution to journal › Journal article › Research › peer-review
Obesity--is it a genetic disorder?
Loos, Ruth & Bouchard, C., Nov 2003, In: Journal of Internal Medicine. 254, 5, p. 401-25 25 p.Research output: Contribution to journal › Review › Research › peer-review
Oligogenic Architecture of Rare Noncoding Variants Distinguishes 4 Congenital Heart Disease Phenotypes
Yu, M., Aguirre, M., Jia, M., Gjoni, K., Cordova-Palomera, A., Munger, C., Amgalan, D., Rosa Ma, X., Pereira, A., Tcheandjieu, C., Seidman, C., Seidman, J., Tristani-Firouzi, M., Chung, W., Goldmuntz, E., Srivastava, D., Loos, R. J. F., Chami, N., Cordell, H., Dreßen, M. & 8 others, , 2023, In: Circulation: Genomic and Precision Medicine. 16, 3, p. 258-266 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PFAS Exposures and the Human Metabolome: A Systematic Review of Epidemiological Studies
India-Aldana, S., Yao, M., Midya, V., Colicino, E., Chatzi, L., Chu, J., Gennings, C., Jones, D. P., Loos, Ruth, Setiawan, V. W., Smith, M. R., Walker, R. W., Barupal, D., Walker, D. I. & Valvi, D., 2023, In: Current Pollution Reports. 9, p. 510-568Research output: Contribution to journal › Review › Research › peer-review
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Parental Education and Genetics of BMI from Infancy to Old Age: A Pooled Analysis of 29 Twin Cohorts
Silventoinen, K., Jelenkovic, A., Latvala, A., Yokoyama, Y., Sund, R., Sugawara, M., Tanaka, M., Matsumoto, S., Aaltonen, S., Piirtola, M., Freitas, D. L., Maia, J. A., Oncel, S. Y., Aliev, F., Ji, F., Ning, F., Pang, Z., Rebato, E., Saudino, K. J., Cutler, T. L. & 53 others, , 2019, In: Obesity. 27, 5, p. 855-865 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Persistent thinness and anorexia nervosa differ on a genomic level
Hübel, C., Abdulkadir, M., Herle, M., Palmos, A. B., Loos, Ruth, Breen, G., Micali, Nadia & Bulik, C. M., 2024, In: European Journal of Human Genetics. 32, 1, p. 117-124Research output: Contribution to journal › Journal article › Research › peer-review
ID: 183694311
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Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
Research output: Contribution to journal › Journal article › Research › peer-review
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266
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A Large-Scale Multi-ancestry Genome-wide Study Accounting for Smoking Behavior Identifies Multiple Significant Loci for Blood Pressure
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Data Descriptor: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls
Research output: Contribution to journal › Journal article › Research › peer-review
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