Bo Torben Porse

Bo Torben Porse

Professor, Clinical Professor

Member of:

  • Internal Medicine: Haematology

ORCID: 0000-0001-6043-0844

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  1. Published

    The ASXL1-G643W variant accelerates the development of CEBPA mutant acute myeloid leukemia

    D'Altri, T., Wilhelmson, Anna, Schuster, Mikkel Bruhn, Wenzel, Anne, Kalvisa, A., Pundhir, Sachin, Hansen, A. M. & Porse, Bo Torben, 2021, In: Haematologica. 106, 4, p. 1000-1007 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. The International Human Epigenome Consortium: A Blueprint for Scientific Collaboration and Discovery

    Stunnenberg, H. G., Hirst, M., International Human Epigenome Consortium, I. H. E. C., Helin, K. & Porse, Bo Torben, 17 Nov 2016, In: Cell. 167, 5, p. 1145-1149 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cells.

    Bracken, A. P., Kleine-Kohlbrecher, D., Dietrich, N., Pasini, D., Gargiulo, G., Beekman, C., Theilgaard-Mønch, Kim, Minucci, S., Porse, Bo Torben, Marine, J., Hansen, K. H. & Helin, K., 2007, In: Genes & Development. 21, 5, p. 525-30 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The antibiotic micrococcin acts on protein L11 at the ribosomal GTPase centre.

    Porse, Bo Torben, Cundliffe, E. & Garrett, Roger Antony, 1999, In: Journal of Molecular Biology. 287, 1, p. 33-45 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The antibiotic thiostrepton inhibits a functional transition within protein L11 at the ribosomal GTPase centre

    Porse, Bo Torben, Leviev, I., Mankin, A. S. & Garrett, R. A., 1998, In: Journal of Molecular Biology. 276, 2, p. 391-404 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The donor substrate site within the peptidyl transferase loop of 23 S rRNA and its putative interactions with the CCA-end of N-blocked aminoacyl-tRNA(Phe).

    Porse, Bo Torben, Thi-Ngoc, H. P. & Garrett, R. A., 1996, In: Journal of Molecular Biology. 264, 3, p. 472-83 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The eha research roadmap: normal hematopoiesis

    Jaffredo, T., Balduini, A., Bigas, A., Bernardi, R., Bonnet, D., Canque, B., Charbord, P., Cumano, A., Delwel, R., Durand, C., Fibbe, W., Forrester, L., De Franceschi, L., Ghevaert, C., Gjertsen, B., Gottgens, B., Graf, T., Heidenreich, O., Hermine, O., Higgs, D. & 21 others, Kleanthous, M., Klump, H., Kouskoff, V., Krause, D., Lacaud, G., Lo Celso, C., Martens, J. H. A., Méndez-Ferrer, S., Menendez, P., Oostendorp, R., Philipsen, S., Porse, Bo Torben, Raaijmakers, M., Robin, C., Stunnenberg, H., Theilgaard-Mønch, Kim, Touw, I., Vainchenker, W., Corrons, J. L. V., Yvernogeau, L. & Schuringa, J. J., 2021, In: HemaSphere. 5, 12, e669.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    The functional consequences of intron retention: Alternative splicing coupled to NMD as a regulator of gene expression

    Ge, Y. & Porse, Bo Torben, 18 Dec 2013, In: BioEssays.

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    The histone demethylase KDM5C functions as a tumor suppressor in AML by repression of bivalently marked immature genes

    Trempenau, M. L., Schuster, Mikkel Bruhn, Pundhir, Sachin, Araújo Pereira, Mafalda, Kalvisa, A., Tapia, Marta Cecylia, Su, Jinyu, Ge, Y., de Boer, Bauke, Balhuizen, Alexander, Bagger, F. O., Shliaha, P., Sroczynska, P., Walfridsson, J., Grønbæk, Kirsten, Theilgaard-Mønch, Kim, Jensen, O. N., Helin, K. & Porse, Bo Torben, 2023, In: Leukemia. 37, 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The impact of SWI/SNF and NuRD inactivation on gene expression is tightly coupled with levels of RNA polymerase II occupancy at promoters

    Pundhir, Sachin, Su, Jinyu, Tapia, Marta Cecylia, Hansen, A. M., Haile, James Seymour, Hansen, K. & Porse, Bo Torben, 2023, In: Genome Research. 33, 3, p. 332-345 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The multifaceted functions of C/EBPα in normal and malignant haematopoiesis

    Ohlsson, E., Schuster, Mikkel Bruhn, Hasemann, M. & Porse, Bo Torben, Apr 2016, In: Leukemia. 30, 4, p. 767-75 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  12. Published

    The presence of C/EBPα and its degradation are both required for TRIB2-mediated leukaemia

    O'Connor, C., Lohan, F., Campos, J., Ohlsson, E., Salomè, M., Forde, C., Artschwager, R., Liskamp, R. M., Cahill, M. R., Kiely, P. A., Porse, Bo Torben & Keeshan, K., 6 Oct 2016, In: Oncogene. 35, 40, p. 5272-5281 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The proline-histidine-rich CDK2/CDK4 interaction region of C/EBPalpha is dispensable for C/EBPalpha-mediated growth regulation in vivo.

    Porse, Bo Torben, Pedersen, T. A., Hasemann, M. S., Schuster, Mikkel Bruhn, Kirstetter, P., Luedde, T., Damgaard, I., Kurz, E., Schjerling, C. K. & Nerlov, C., 2006, In: Molecular and Cellular Biology. 26, 3, p. 1028-37 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The splicing factor RBM25 controls MYC activity in acute myeloid leukemia

    Ge, Y., Schuster, Mikkel Bruhn, Pundhir, Sachin, Rapin, N., Bagger, F. O., Sidiropoulos, N., Hashem, N. & Porse, Bo Torben, 2019, In: Nature Communications. 10, 1, p. 1-14 14 p., 172.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Therapeutic Potential of an Immune-Modulatory Vaccination Targeting Myeloid-Derived Suppressor Cells in Myelodysplastic Syndrome

    Bentivegna, Sofia, Holmstrøm, M., Balhuizen, Alexander, Almosailleakh, M., Perez Penco, Maria, Porse, Bo Torben, Andersen, Mads Hald & Grønbæk, Kirsten, 2022, In: Blood. 140, Suppl. 1, p. 4007-4008 2 p.

    Research output: Contribution to journal › Conference abstract in journal › Research

  16. Published

    Transcription factor-driven coordination of cell cycle exit and lineage-specification in vivo during granulocytic differentiation: In memoriam Professor Niels Borregaard

    Theilgaard-Mønch, Kim, Pundhir, Sachin, Reckzeh, K., Su, Jinyu, Tapia, Marta Cecylia, Furtwängler, Benjamin, Jendholm, J., Jakobsen, J. S., Hasemann, M. S., Knudsen, K. J., Cowland, J. B., Fossum, A., Schoof, E., Schuster, Mikkel Bruhn & Porse, Bo Torben, 2022, In: Nature Communications. 13, 1, 17 p., 3595.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Transcriptional Heterogeneity and Lineage Commitment in Myeloid Progenitors

    Paul, F., Arkin, Y., Giladi, A., Jaitin, D. A., Kenigsberg, E., Keren-Shaul, H., Winter, D., Lara-Astiaso, D., Gury, M., Weiner, A., David, E., Cohen, N., Lauridsen, F. K. B., Haas, S., Schlitzer, A., Mildner, A., Ginhoux, F., Jung, S., Trumpp, A., Porse, B. T. & 2 others, Tanay, A. & Amit, I., 17 Dec 2015, In: Cell. 163, 7, p. 1663-77 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Transgene mus som sygdomsmodeller.

    Schuster, Mikkel Bruhn & Porse, Bo Torben, 2003, In: Ugeskrift for læger. 165, 8, p. 793-6 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    UPF2 is a critical regulator of liver development, function and regeneration

    Thoren, L. A., Nørgaard, G. A., Weischenfeldt, Joachim Lütken, Waage, J., Jakobsen, J. S., Damgaard, I., Bergström, F. C., Blom, A. M., Borup, R., Bisgaard, Hanne Cathrine & Porse, Bo Torben, 2010, In: PLoS ONE. 5, 7, p. e11650

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    UPF2, a nonsense-mediated mRNA decay factor, is required for prepubertal Sertoli cell development and male fertility by ensuring fidelity of the transcriptome

    Bao, J., Tang, C., Yuan, S., Porse, Bo Torben & Yan, W., 2015, In: Development (Cambridge, England). 142, p. 352-362 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    UPF2-dependent nonsense-mediated mRNA decay pathway is essential for spermatogenesis by selectively eliminating longer 3'UTR transcripts

    Bao, J., Vitting-Seerup, K., Waage, J. E., Tang, C., Ge, Y., Porse, Bo Torben & Yan, W., 2016, In: P L o S Genetics. 12, 5, 24 p., e1005863.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    UV-induced modifications in the peptidyl transferase loop of 23S rRNA dependent on binding of the streptogramin B antibiotic, pristinamycin IA.

    Porse, Bo Torben, Kirillov, S. V., Awayez, M. J. & Garrett, R. A., 1999, In: RNA: A publication of the RNA Society. 5, 4, p. 585-95 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    microRNA-9 targets the long non-coding RNA MALAT1 for degradation in the nucleus

    Leucci, E., Patella, F., Waage, J., Holmstrøm, K., Lindow, M., Porse, Bo Torben, Kauppinen, S. & Lund, Anders H., 29 Aug 2013, In: Scientific Reports. 3, p. 2535

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    shRNA screening identifies JMJD1C as being required for leukemia maintenance

    Sroczynska, P., Cruickshank, V. A., Bukowski, J., Miyagi, S., Bagger, F. O., Walfridsson, J., Schuster, Mikkel Bruhn, Porse, Bo Torben & Helin, K., 5 Feb 2014, In: Blood (online).

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    spliceR: an R package for classification of alternative splicing and prediction of coding potential from RNA-seq data

    Vitting-Seerup, K., Porse, Bo Torben, Sandelin, Albin Gustav & Waage, J., 2014, In: B M C Bioinformatics. 15, p. 1-7 7 p., 81.

    Research output: Contribution to journal › Journal article › Research › peer-review

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