Børge Nordestgaard
Clinical Professor
Department of Clinical Medicine
Borgmester Ib Juuls Vej 1, 2730 Herlev
Member of:
Clinical Biochemistry
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11q13 is a Susceptibility Locus for Hormone Receptor Positive Breast Cancer
Lambrechts, D., Truong, T., Justenhoven, C., Humphreys, M. K., Wang, J., Hopper, J. L., Dite, G. S., Apicella, C., Southey, M. C., Schmidt, M. K., Broeks, A., Cornelissen, S., Hien, R. V., Sawyer, E., Tomlinson, I., Kerin, M., Miller, N., Milne, R. L., Zamora, M. P., Pérez, J. I. A. & 31 others, , 2012, In: Human Mutation.Research output: Contribution to journal › Journal article › Research › peer-review
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164Ile allele in the beta2-Adrenergic receptor gene is associated with risk of elevated blood pressure in women. The Copenhagen City Heart Study
Sethi, A., Tybjærg-Hansen, A., Jensen, G. B., Nordestgaard, B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2005, In: Pharmacogenetics and Genomics. 15, 9, p. 633-45 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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19p13.1 is a triple-negative-specific breast cancer susceptibility locus
Stevens, K. N., Fredericksen, Z., Vachon, C. M., Wang, X., Margolin, S., Lindblom, A., Nevanlinna, H., Greco, D., Aittomäki, K., Blomqvist, C., Chang-Claude, J., Vrieling, A., Flesch-Janys, D., Sinn, H-P., Wang-Gohrke, S., Nickels, S., Brauch, H., Ko, Y-D., Fischer, H-P., Schmutzler, R. K. & 31 others, , 2012, In: Cancer Research. 72, 7, p. 1795-803 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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2019 vs. 2016 ESC/EAS statin guidelines for primary prevention of atherosclerotic cardiovascular disease
Mortensen, M. B. & Nordestgaard, Børge, 2020, In: European Heart Journal. 41, 31, p. 3005-3015 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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25-Hydroxyvitamin D and Risk of Osteoporotic Fractures: Mendelian Randomization Analysis in 2 Large Population-Based Cohorts
Çolak, Y., Afzal, Shoaib & Nordestgaard, Børge, 2020, In: Clinical Chemistry. 66, 5, p. 676-685 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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25-Hydroxyvitamin D and symptomatic ischemic stroke: An Original Study and Meta-Analysis
Brøndum-Jacobsen, P., Nordestgaard, Børge, Schnohr, P. & Benn, M., 2013, In: Annals of Neurology. 73, 1, p. 38-47Research output: Contribution to journal › Journal article › Research › peer-review
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25-hydroxyvitamin D concentrations and risk of venous thromboembolism in the general population with 18,791 participants
Brøndum-Jacobsen, P., Benn, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2013, In: Journal of Thrombosis and Haemostasis. 11, 3, p. 423-431Research output: Contribution to journal › Journal article › Research › peer-review
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25-hydroxyvitamin d levels and risk of ischemic heart disease, myocardial infarction, and early death: population-based study and meta-analyses of 18 and 17 studies
Brøndum-Jacobsen, P., Benn, M., Jensen, G. B. & Nordestgaard, Børge, 2012, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 32, 11, p. 2794-802 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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7q21-rs6964587 and breast cancer risk: an extended case-control study by the Breast Cancer Association Consortium
Milne, R. L., Lorenzo-Bermejo, J., Burwinkel, B., Malats, N., Arias, J. I., Zamora, M. P., Benítez, J., Humphreys, M. K., García-Closas, M., Chanock, S. J., Lissowska, J., Sherman, M. E., Mannermaa, A., Kataja, V., Kosma, V-M., Nevanlinna, H., Heikkinen, T., Aittomäki, K., Blomqvist, C., Anton-Culver, H. & 31 others, , 2011, In: Journal of Medical Genetics. 48, 10, p. 698-702 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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9q31.2-rs865686 as a susceptibility locus for estrogen receptor-positive breast cancer: evidence from the Breast Cancer Association Consortium
Warren, H., Dudbridge, F., Fletcher, O., Orr, N., Johnson, N., Hopper, J. L., Apicella, C., Southey, M. C., Mahmoodi, M., Schmidt, M. K., Broeks, A., Cornelissen, S., Braaf, L. M., Muir, K. R., Lophatananon, A., Chaiwerawattana, A., Wiangnon, S., Fasching, P. A., Beckmann, M. W., Ekici, A. B. & 31 others, , 2012, In: Cancer Epidemiology, Biomarkers & Prevention. 21, 10, p. 1783-91 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Angiotensinogen and ACE gene polymorphisms and risk of atrial fibrillation in the general population
Ravn, L. S., Benn, Marianne, Nordestgaard, Børge, Sethi, A. A., Agerholm-Larsen, B., Jensen, G. B. & Tybjærg-Hansen, Anne, 2008, In: Pharmacogenetics and Genomics (Print Edition). 18, 6, p. 525-533 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ABCA7 and risk of dementia and vascular disease in the Danish population
Kjeldsen, E. W., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: Annals of Clinical and Translational Neurology. 5, 1, p. 41-51 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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AHRR (cg05575921) hypomethylation marks smoking behaviour, morbidity and mortality
Bojesen, Stig Egil, Timpson, N., Relton, C., Davey Smith, G. & Nordestgaard, Børge, Jul 2017, In: Thorax. 72, 7, p. 646-653 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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APOC3 Loss-of-Function Mutations, Remnant Cholesterol, Low-Density Lipoprotein Cholesterol, and Cardiovascular Risk: Mediation- and Meta-Analyses of 137 895 Individuals
Wulff, A. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 3, p. 660-668Research output: Contribution to journal › Journal article › Research › peer-review
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APOE and dementia – resequencing and genotyping in 105,597 individuals
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2020, In: Alzheimer's and Dementia. 16, 12, p. 1624-1637 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CYP3A7*1C allele: linking premenopausal oestrone and progesterone levels with risk of hormone receptor-positive breast cancers
Johnson, N., Maguire, S., Morra, A., Kapoor, P. M., Tomczyk, K., Jones, M. E., Schoemaker, M. J., Gilham, C., Bolla, M. K., Wang, Q., Dennis, J., Ahearn, T. U., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Arndt, V., Aronson, K. J., Augustinsson, A., Baynes, C., Freeman, L. E. B. & 34 others, , 2021, In: British Journal of Cancer. 124, 4, p. 842-854 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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JAK2V617F Somatic Mutation In The General Population: Myeloproliferative Neoplasm Development And Progression Rate
Nielsen, C., Bojesen, Stig Egil, Nordestgaard, Børge, Kofoed, K. F. & Birgens, H. S., Sep 2014, In: Haematologica. 99, 9, p. 1448-1455 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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KLK3 SNP–SNP interactions for prediction of prostate cancer aggressiveness
Lin, H. Y., Huang, P. Y., Cheng, C. H., Tung, H. Y., Fang, Z., Berglund, A. E., Chen, A., French-Kwawu, J., Harris, D., Pow-Sang, J., Yamoah, K., Cleveland, J. L., Awasthi, S., Rounbehler, R. J., Gerke, T., Dhillon, J., Eeles, R., Kote-Jarai, Z., Muir, K., Eeles, R. & 28 others, , 2021, In: Scientific Reports. 11, 1, 9264.Research output: Contribution to journal › Journal article › Research › peer-review
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PALB2, CHEK2 and ATM rare variants and cancer risk: data from COGS
Southey, M. C., Goldgar, D. E., Winqvist, R., Pylkäs, K., Couch, F., Tischkowitz, M., Foulkes, W. D., Dennis, J., Michailidou, K., van Rensburg, E. J., Heikkinen, T., Nevanlinna, H., Hopper, J. L., Dörk, T., Claes, K. B., Reis-Filho, J., Teo, Z. L., Radice, P., Catucci, I., Peterlongo, P. & 31 others, , Dec 2016, In: Journal of Medical Genetics. 53, 12, p. 800-811Research output: Contribution to journal › Journal article › Research › peer-review
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RAD51B in Familial Breast Cancer
Pelttari, L. M., Khan, S., Vuorela, M., Kiiski, J. I., Vilske, S., Nevanlinna, V., Ranta, S., Schleutker, J., Winqvist, R., Kallioniemi, A., Dörk, T., Bogdanova, N. V., Figueroa, J., Pharoah, P. D. P., Schmidt, M. K., Dunning, A. M., García-Closas, M., Bolla, M. K., Dennis, J., Michailidou, K. & 31 others, , 2016, In: PLOS ONE. 11, 5, 18 p., e0153788.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SCARB1 Gene Variants Are Associated With the Phenotype of Combined High High-Density Lipoprotein Cholesterol and High Lipoprotein (a)
Yang, X., Sethi, A. A., Yanek, L. R., Knapper, C., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Becker, D. M., Mathias, R. A., Remaley, A. T. & Becker, L. C., Oct 2016, In: Circulation: Cardiovascular Genetics. 9, 5, p. 408-418 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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TP53 Arg72Pro, mortality after cancer, and all-cause mortality in 105,200 individuals
Kodal, J. B., Vedel-Krogh, S., Kobylecki, C. J., Nordestgaard, Børge & Bojesen, Stig Egil, 2017, In: Scientific Reports. 7, 8 p., 336.Research output: Contribution to journal › Journal article › Research › peer-review
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A Bidirectional Mendelian Randomization Study to evaluate the causal role of reduced blood vitamin D levels with type 2 diabetes risk in South Asians and Europeans
Bejar, C. A., Goyal, S., Afzal, S., Mangino, M., Zhou, A., van der Most, P. J., Bao, Y., Gupta, V., Smart, M. C., Walia, G. K., Verweij, N., Power, C., Prabhakaran, D., Singh, J. R., Mehra, N. K., Wander, G. S., Ralhan, S., Kinra, S., Kumari, M., de Borst, M. H. & 5 others, , 2021, In: Nutrition Journal. 20, 1, p. 1-11 71.Research output: Contribution to journal › Journal article › Research › peer-review
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A Genetic Risk Score to Personalize Prostate Cancer Screening, Applied to Population Data
Huynh-Le, M-P., Fan, C. C., Karunamuni, R., Walsh, E. I., Turner, E. L., Lane, J. A., Martin, R. M., Neal, D. E., Donovan, J. L., Hamdy, F. C., Parsons, J. K., Eeles, R. A., Easton, D. F., Kote-Jarai, Z., Amin Al Olama, A., Benlloch Garcia, S., Muir, K., Grönberg, H., Wiklund, F., Aly, M. & 31 others, , 2020, In: Cancer Epidemiology, Biomarkers & Prevention. 29, 9, p. 1731-1738Research output: Contribution to journal › Journal article › Research › peer-review
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A Large-Scale Analysis of Genetic Variants within Putative miRNA Binding Sites in Prostate Cancer
Stegeman, S., Amankwah, E., Klein, K., O'Mara, T. A., Kim, D., Lin, H-Y., Permuth-Wey, J., Sellers, T. A., Srinivasan, S., Eeles, R., Easton, D., Kote-Jarai, Z., Amin Al Olama, A., Benlloch, S., Muir, K., Giles, G. G., Wiklund, F., Gronberg, H., Haiman, C. A., Schleutker, J. & 20 others, , 1 Apr 2015, In: Cancer Discovery. 5, 4, p. 368-79 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Review of Major Danish Biobanks: Advantages and Possibilities of Health Research in Denmark
Laugesen, K., Mengel-From, J., Christensen, K., Olsen, J., Hougaard, D. M., Boding, L., Olsen, A., Erikstrup, C., Hetland, M. L., Høgdall, E., Kjaergaard, A. D., Sørensen, E., Brügmann, A., Petersen, E. R. B., Brandslund, I., Nordestgaard, B. G., Jensen, G. B., Skajaa, N., Troelsen, F. S., Fuglsang, C. H. & 2 others, , 2023, In: Clinical Epidemiology. 15, p. 213-239 27 p.Research output: Contribution to journal › Review › Research › peer-review
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A Test in Context: Lipid Profile, Fasting Versus Nonfasting
Nordestgaard, Børge, Sep 2017, In: Journal of the American College of Cardiology. 70, 13, p. 1637-1646 10 p.Research output: Contribution to journal › Review › Research › peer-review
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A genome-wide association scan (GWAS) for mean telomere length within the COGS project: identified loci show little association with hormone-related cancer risk
Pooley, K. A., Bojesen, S. E., Weischer, M., Nielsen, S. F., Thompson, D., Amin Al Olama, A., Michailidou, K., Tyrer, J. P., Benlloch, S., Brown, J., Audley, T., Luben, R., Khaw, K-T., Neal, D. E., Hamdy, F. C., Donovan, J. L., Kote-Jarai, Z., Baynes, C., Shah, M., Bolla, M. K. & 15 others, , 2013, In: Human Molecular Genetics. 22, 24, p. 5056-5064Research output: Contribution to journal › Journal article › Research › peer-review
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A genome-wide gene-environment interaction study of breast cancer risk for women of European ancestry
Middha, P., Wang, X., Behrens, S., Bolla, M. K., Wang, Q., Dennis, J., Michailidou, K., Ahearn, T. U., Andrulis, I. L., Anton-Culver, H., Arndt, V., Aronson, K. J., Auer, P. L., Augustinsson, A., Baert, T., Freeman, L. E. B., Becher, H., Beckmann, M. W., Benitez, J., Bojesen, S. E. & 33 others, , 2023, In: Breast cancer research : BCR. 25, 1, 13 p., 93.Research output: Contribution to journal › Journal article › Research › peer-review
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A large-scale assessment of two-way SNP interactions in breast cancer susceptibility using 46,450 cases and 42,461 controls from the breast cancer association consortium
Milne, R. L., Herranz, J., Michailidou, K., Dennis, J., Tyrer, J. P., Zamora, M. P., Arias-Perez, J. I., González-Neira, A., Pita, G., Alonso, M. R., Wang, Q., Bolla, M. K., Czene, K., Eriksson, M., Humphreys, K., Darabi, H., Li, J., Anton-Culver, H., Neuhausen, S. L., Ziogas, A. & 31 others, , 1 Apr 2014, In: Human Molecular Genetics. 23, 7, p. 1934-1946 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A meta-analysis of genome-wide association studies to identify prostate cancer susceptibility loci associated with aggressive and non-aggressive disease
Amin Al Olama, A., Kote-Jarai, Z., Schumacher, F. R., Wiklund, F., Berndt, S. I., Benlloch, S., Giles, G. G., Severi, G., Neal, D. E., Hamdy, F. C., Donovan, J. L., Hunter, D. J., Henderson, B. E., Thun, M. J., Gaziano, M., Giovannucci, E. L., Siddiq, A., Travis, R. C., Cox, D. G., Canzian, F. & 31 others, , 2013, In: Human Molecular Genetics. 22, 2, p. 408-415 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A new start for triglycerides and remnant cholesterol-nonfasting
Nordestgaard, Børge, Aug 2017, In: Clinical Chemistry. 63, 8, p. 1418-1419 2 p.Research output: Contribution to journal › Comment/debate › Research
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A population-based study of morbidity and mortality in mannose-binding lectin deficiency
Dahl, M., Tybjærg-Hansen, Anne, Schnohr, P. & Nordestgaard, Børge, 17 May 2004, In: Journal of Experimental Medicine. 199, 10, p. 1391-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A possible explanation for the contrasting results of REDUCE-IT vs. STRENGTH: cohort study mimicking trial designs
Doi, T., Langsted, A. & Nordestgaard, Børge, 2021, In: European Heart Journal. 42, 47, p. 4807-4817 11 p., 555.Research output: Contribution to journal › Journal article › Research › peer-review
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A randomized trial of rosuvastatin in the prevention of venous thromboembolism
Glynn, R. J., Danielson, E., Fonseca, F. A. H., Genest, J., Gotto, A. M., Kastelein, J. J. P., Koenig, W., Libby, P., Lorenzatti, A. J., MacFadyen, J. G., Nordestgaard, Børge, Shepherd, J., Willerson, J. T. & Ridker, P. M., 2009, In: New England Journal of Medicine. 360, 18, p. 1851-61 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A rare genetic variant in the manganese transporter SLC30A10 and elevated liver enzymes in the general population
Seidelin, A. S., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Yaghootkar, H. & Stender, Stefan, 2022, In: Hepatology International. 16, 3, p. 702-711Research output: Contribution to journal › Journal article › Research › peer-review
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A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease
Holmes, M. V., Frikke-Schmidt, R., Melis, D., Luben, R., Asselbergs, F. W., Boer, J. M. A., Cooper, J., Palmen, J., Horvat, P., Engmann, J., Li, K-W., Onland-Moret, N. C., Hofker, M. H., Kumari, M., Keating, B. J., Hubacek, J. A., Adamkova, V., Kubinova, R., Bobak, M., Khaw, K-T. & 6 others, , Nov 2014, In: Atherosclerosis. 237, 1, p. 5-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A third of nonfasting plasma cholesterol is in remnant lipoproteins: Lipoprotein subclass profiling in 9293 individuals
Balling, M., Langsted, A., Afzal, Shoaib, Varbo, A., Davey Smith, G. & Nordestgaard, Børge, 2019, In: Atherosclerosis. 286, p. 97-104 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A transcriptome-wide association study of 229,000 women identifies new candidate susceptibility genes for breast cancer
Wu, L., Shi, W., Long, J., Guo, X., Michailidou, K., Beesley, J., Bolla, M. K., Shu, X-O., Lu, Y., Cai, Q., Al-Ejeh, F., Rozali, E., Wang, Q., Dennis, J., Li, B., Zeng, C., Feng, H., Gusev, A., Barfield, R. T., Andrulis, I. L. & 31 others, , 2018, In: Nature Genetics. 50, 7, p. 968-978 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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AA9int: SNP interaction pattern search using non-hierarchical additive model set
PRACTICAL consortium, P. C., 2018, In: Bioinformatics. 34, 24, p. 4141-4150 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ABC transporter genes and risk of type 2 diabetes: a study of 40,000 individuals from the general population
Schou, J., Tybjærg-Hansen, Anne, Møller, H. J., Nordestgaard, Børge & Frikke-Schmidt, R., 2012, In: Diabetes Care. 35, 12, p. 2600-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ACC/AHA guidelines superior to ESC/EAS guidelines for primary prevention with statins in non-diabetic Europeans: The Copenhagen General Population Study
Mortensen, M. B., Nordestgaard, Børge, Afzal, Shoaib & Falk, E., 2017, In: European Heart Journal. 38, 8, p. 586-594Research output: Contribution to journal › Journal article › Research › peer-review
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ADH1B and ADH1C Genotype, Alcohol Consumption and Biomarkers of Liver Function: Findings from a Mendelian Randomization Study in 58,313 European Origin Danes
Lawlor, D. A., Benn, Marianne, Zuccolo, L., De Silva, N. M. G., Tybjaerg-Hansen, A., Smith, G. D. & Nordestgaard, Børge, 2014, In: PLOS ONE. 9, 12, p. 1-14 14 p., e114294.Research output: Contribution to journal › Journal article › Research › peer-review
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AHRR hypomethylation as an epigenetic marker of smoking history predicts risk of myocardial infarction in former smokers
Langsted, A., Bojesen, Stig Egil, Stroes, E. S. G. & Nordestgaard, Børge, 2020, In: Atherosclerosis. 312, p. 8-15 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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AHRR hypomethylation, lung function, lung function decline and respiratory symptoms
Kodal, J. B., Kobylecki, C. J., Vedel-Krogh, S., Nordestgaard, Børge & Bojesen, Stig Egil, 2018, In: The European Respiratory Journal. 51, 3, 1701512.Research output: Contribution to journal › Journal article › Research › peer-review
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APOE and vascular disease: Sequencing and genotyping in general population cohorts
Rasmussen, Katrine Laura, Luo, J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: Atherosclerosis. 385, 9 p., 117218.Research output: Contribution to journal › Journal article › Research › peer-review
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AT1 mutations and risk of atrial fibrillation based on genotypes from 71,000 individuals from the general population
Marott, S. C. W., Nordestgaard, Børge, Jensen, G. B., Tybjærg-Hansen, Anne & Benn, M., 2013, In: British Journal of Clinical Pharmacology. p. Epub ahead of printResearch output: Contribution to journal › Journal article › Research › peer-review
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Absolute 10-year risk of dementia by age, sex and APOE genotype: A population-based cohort study
Rasmussen, K. L., Tybjarg-Hansen, A., Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: CMAJ. 190, 35, p. E1033-E1041Research output: Contribution to journal › Journal article › Research › peer-review
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Absolute and Relative Risks of Hematologic Disease and Cause-Specific Death in Individuals with Incidentally Discovered Thrombocytopenia: A Prospective Study of Two Independent General Population Cohorts Including 486,782 Individuals from the United Kingdom and Denmark
Juhl, A. R., Glenthøj, Andreas Birkedal, Nordestgaard, Børge, Petersen, J., Dahl, Morten, Ellervik, Christina, Bojesen, Stig Egil & Helby, J., 2023, In: Blood. 142, Supplement 1, p. 395 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Additional SNPs improve risk stratification of a polygenic hazard score for prostate cancer
UKGPCS Collaborators, U. C., APCB BioResource (Australian Prostate Cancer BioResource), A. B. (. P. C. B., IMPACT Study Steering Committee and Collaborators, I. S. S. C. A. C., Canary PASS Investigators, C. P. I., Profile Study Steering Committee, P. S. S. C. & PRACTICAL consortium, P. C., 2021, In: Prostate Cancer and Prostatic Diseases. 24, 2, p. 532-541 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11241
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RAD51B in Familial Breast Cancer
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Meta-analysis of up to 622,409 individuals identifies 40 novel smoking behaviour associated genetic loci
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Dairy consumption, systolic blood pressure, and risk of hypertension: Mendelian randomization study
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