K. Schmiegelow
Clinical Professor
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TPMT polymorphisms and minimal residual disease after 6-mercaptopurine post-remission consolidation therapy of childhood acute lymphoblastic leukaemia
Dreisig, K., Brünner, E. D., Marquart, Hanne Vibeke Hansen, Helt, L. R., Nersting, J., Frandsen, T. L., Jonsson, O. G., Taskinen, M., Vaitkeviciene, G., Lund, B., Abrahamsson, J., Lepik, K. & Schmiegelow, Kjeld, 2021, In: Pediatric Hematology and Oncology. 38, 3, p. 227-238Research output: Contribution to journal › Journal article › Research › peer-review
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A qualitative study of adolescent cancer survivors perspectives on social support from healthy peers – A RESPECT study
Ingersgaard, M. V., Fridh, M. K., Thorsteinsson, Troels, Adamsen, L., Schmiegelow, Kjeld & Larsen, Hanne Bækgaard, 2021, In: Journal of Advanced Nursing. 77, 4, p. 1911-1920 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute liver failure in a four-year old girl during maintenance therapy of acute lymphoblastic leukemia
Raja, R. A., Wolthers, B. O., Frandsen, T. L., Albertsen, B. K., Schulz, N., Damholt, M. B., Schmiegelow, Kjeld & Jørgensen, M. H., 2021, In: Pediatric Hematology and Oncology. 38, 7, p. 669-675Research output: Contribution to journal › Letter › Research › peer-review
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Acute lymphoblastic leukemia and down syndrome: 6-mercaptopurine and methotrexate metabolites during maintenance therapy
Nordic Society of Paediatric Haematology and Oncology (NOPHO), N. S. O. P. H. A. O. (., 2021, In: Leukemia. 35, p. 863–866 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Aspergillus flavus Infections in Children with Leukemia despite Liposomal Amphotericin-B Prophylaxis
Vissing, N. H., Lausen, B., Hutchings Hoffmann, M., Als-Nielsen, B., Schmiegelow, Kjeld, Helweg-Larsen, J., Arendrup, Maiken Cavling & Nygaard, Ulrikka, 2021, In: Pediatric Infectious Disease Journal. 40, 8, p. 749-752 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Chemotherapy-induced nausea and vomiting in children – the missing evidence
Eliasen, A., Schmiegelow, Kjeld, Rechnitzer, C., Brok, J., Dalhoff, Kim & Mathiasen, R., 2021, In: Adverse Drug Reaction Bulletin. 328, 1, p. 1271-1274Research output: Contribution to journal › Review › Research › peer-review
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DNA-thioguanine concentration and relapse risk in children and young adults with acute lymphoblastic leukemia: an IPD meta-analysis
Toksvang, L. N., Grell, K., Nersting, J., Degn, M., Nielsen, S. N., Abrahamsson, J., Lund, B., Kanerva, J., Jónsson, Ó. G., Lepik, K., Vaitkevičienė, G., Griškevičius, L., Quist-Paulsen, P., Vora, A., Moorman, A. V., Murdy, D., Zimmermann, M., Möricke, A., Bostrom, B., Joshi, J. & 4 others, , 2021, In: Leukemia. 36, p. 33–41 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Detection mode of childhood acute lymphoblastic leukaemia relapse and its effect on survival: a Nordic population-based cohort study
the Nordic Society of Paediatric Haematology and Oncology (NOPHO), T. N. S. O. P. H. A. O. (., 2021, In: British Journal of Haematology. 194, 4, p. 734-744 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamics of leucocyte DNA thioguanine nucleotide levels during maintenance therapy of childhood acute lymphoblastic leukemia
Larsen, R. H., Hjalgrim, L. L., Degn, M., Nersting, J., Als-Nielsen, B., Grell, Kathrine & Schmiegelow, Kjeld, 2021, In: Cancer Chemotherapy and Pharmacology. 88, p. 53–60 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of NT5C2 Germline Variants on 6-Mecaptopurine Metabolism in Children With Acute Lymphoblastic Leukemia
Jiang, C., Yang, W., Moriyama, T., Liu, C., Smith, C., Yang, W., Qian, M., Li, Z., Tulstrup, Morten Rytter, Schmiegelow, Kjeld, Crews, K. R., Zhang, H., Pui, C. H., Evans, W., Relling, M., Bhatia, S. & Yang, J. J., 2021, In: Clinical Pharmacology and Therapeutics. 109, 3, p. 1538-1545Research output: Contribution to journal › Journal article › Research › peer-review
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Evaluation of topical morphine for treatment of oral mucositis in cancer patients
Nielsen, B. N., Friis, S. M., Schmiegelow, Kjeld, Henneberg, S. & Romsing, J., 2021, In: British Journal of Pain. 15, 4, p. 409–417Research output: Contribution to journal › Journal article › Research › peer-review
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Flow cytometric analysis of cerebrospinal fluid improves detection of leukaemic blasts in infants with acute lymphoblastic leukaemia
Thastrup, M., Marquart, Hanne Vibeke Hansen, Levinsen, M., Modvig, S., Abrahamsson, J., Albertsen, B. K., Frost, B. M., Harila-Saari, A., Pesola, J., Ulvmoen, A., Wojcik, D. M., Taskinen, M., Hoffmann, M., Lausen, B., Schmiegelow, Kjeld & on behalf of the Nordic Society of Paediatric Haematology, Oncology (NOPHO), O. B. O. T. N. S. O. P. H. O. (., 2021, In: British Journal of Haematology. 195, 1, p. 119-122Research output: Contribution to journal › Journal article › Research › peer-review
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Genome-wide association study across pediatric central nervous system tumors implicates shared predisposition and points to 1q25.2 (PAPPA2) and 11p12 (LRRC4C) as novel candidate susceptibility loci
Foss-Skiftesvik, J., Hagen, C. M., Mathiasen, R., Adamsen, D., Bækvad-Hansen, M., Børglum, A. D., Nordentoft, Merete, Werge, Thomas, Christiansen, M., Schmiegelow, Kjeld, Juhler, Marianne, Mortensen, P. B., Hougaard, D. M. & Bybjerg-Grauholm, J., 2021, In: Child's Nervous System. 37, p. 819–830Research output: Contribution to journal › Journal article › Research › peer-review
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Genomforskningsprojekt påviser TP53-mutation hos en pige med rabdomyosarkom
Behrendt-Møller, I., Stoltze, U., Hjalgrim, L. L., Hansen, Thomas van Overeem, Schmiegelow, Kjeld & Wadt, Karin Anna Wallentin, 9 Aug 2021, In: Ugeskrift for Laeger. 183, 32, 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Have COVID-19 affected ALL epidemiology?
Schmiegelow, Kjeld, 2021, In: Acta Paediatrica, International Journal of Paediatrics. 110, 2, p. 387-388 2 p.Research output: Contribution to journal › Editorial › Research › peer-review
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Health care utilisation following childhood acute lymphoblastic leukaemia: a population-based matched cohort study
Jensen, K. S., Klug Albertsen, B., Schrøder, H., Zalounina Falborg, A., Schmiegelow, Kjeld, Rosthøj, S., Callesen, M. T. & Vedsted, P., 2021, In: BMJ Open. 11, 11, e049847.Research output: Contribution to journal › Journal article › Research › peer-review
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Health care utilisation preceding relapse or second malignant neoplasm after childhood acute lymphoblastic leukaemia: A population-based matched cohort study
Jensen, K. S., Klug Albertsen, B., Schrøder, H., Zalounina Falborg, A., Schmiegelow, Kjeld, Rosthøj, S., Callesen, M. T. & Vedsted, P., 2021, In: BMJ Open. 11, 8, e050285.Research output: Contribution to journal › Journal article › Research › peer-review
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Hepatic sinusoidal obstruction syndrome and short-term application of 6-thioguanine in pediatric acute lymphoblastic leukemia
Stanulla, M., Schaeffeler, E., Möricke, A., Buchmann, S., Zimmermann, M., Igel, S., Schmiegelow, K., Flotho, C., Hartmann, H., Illsinger, S., Sauerbrey, A., Junk, S. V., Schütte, P., Hinze, L., Lauten, M., Modlich, S., Kolb, R., Rossig, C., Schwabe, G., Gnekow, A. K. & 7 others, , 2021, In: Leukemia. 35, 9, p. 2650-2657 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Home-based cognitive behavioural therapy for families of young children with cancer (FAMOS): A nationwide randomised controlled trial
Salem, H., Kazak, A. E., Andersen, E. W., Belmonte, F., Johansen, Christoffer, Schmiegelow, Kjeld, Winther, J. F., Wehner, P. S., Hasle, H., Rosthøj, S. & Bidstrup, Pernille Envold Hansen, 2021, In: Pediatric Blood and Cancer. 68, 3, 12 p., e28853.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of acute lymphoblastic leukemia induction therapy: findings from metabolomics on non-fasted plasma samples from a biorepository
Saito, T., Wei, Y., Wen, L., Srinivasan, C., Wolthers, B. O., Tsai, C. Y., Harris, M. H., Stevenson, K., Byersdorfer, C., Oparaji, J. A., Fernandez, C., Mukherjee, A., Abu-El-Haija, M., Agnihotri, S., Schmiegelow, K., Showalter, M. R., Fogle, P. W., McCulloch, S., Contrepois, K., Silverman, L. B. & 2 others, , 2021, In: Metabolomics. 17, 7, 64.Research output: Contribution to journal › Journal article › Research › peer-review
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Increments in DNA-thioguanine level during thiopurine enhanced maintenance therapy of acute lymphoblastic leukemia
Larsen, R. H., Utke Rank, C., Grell, Kathrine, Nørgaard Møller, L., Malthe Overgaard, U., Kampmann, P., Nersting, J., Degn, M., Nygaard Nielsen, S., Holst, H., Klug Albertsen, B., Skov Wehner, P., Thude Callesen, M., Kanerva, J., Leth Frandsen, T., Als-Nielsen, B., Lyngsie Hjalgrim, L. & Schmiegelow, Kjeld, 2021, In: Haematologica. 106, 11, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inotuzumab ozogamicin in infants and young children with relapsed or refractory acute lymphoblastic leukaemia: a case series*
Brivio, E., Chantrain, C. F., Gruber, T. A., Thano, A., Rialland, F., Contet, A., Elitzur, S., Dalla-Pozza, L., Kállay, K. M., Li, C. K., Kato, M., Markova, I., Schmiegelow, Kjeld, Bodmer, N., Breese, E. H., Hoogendijk, R., Pieters, R. & Zwaan, C. M., 2021, In: British Journal of Haematology. 193, 6, p. 1172-1177Research output: Contribution to journal › Journal article › Research › peer-review
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Maintenance therapy and risk of osteonecrosis in children and young adults with acute lymphoblastic leukemia: a NOPHO ALL2008 sub-study
Toksvang, L. N., Andres-Jensen, L., Rank, C. U., Niinimaki, R., Nersting, J., Nielsen, S. N., Mogensen, S. S., Harila-Saari, A., Abrahamsson, J., Joelsson, J., Overgaard, U. M., Quist-Paulsen, P., Griskevicius, L., Jonsson, O. G., Vaitkeviciene, G., Frandsen, T. L., Toft, N., Grell, Kathrine & Schmiegelow, Kjeld, 2021, In: Cancer Chemotherapy and Pharmacology. 89, p. 911–917 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Minimal residual disease, long-term outcome, and IKZF1 deletions in children and adolescents with Down syndrome and acute lymphocytic leukaemia: a matched cohort study
Michels, N., Boer, J. M., Enshaei, A., Sutton, R., Heyman, M., Ebert, S., Fiocco, M., de Groot-Kruseman, H. A., van der Velden, V. H. J., Barbany, G., Escherich, G., Vora, A., Trahair, T., Dalla-Pozza, L., Pieters, R., zur Stadt, U., Schmiegelow, Kjeld, Moorman, A. V., Zwaan, C. M. & den Boer, M. L., 2021, In: The Lancet Haematology. 8, 10, p. e700-e710Research output: Contribution to journal › Journal article › Research › peer-review
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Multisystem inflammatory syndrome in children occurred in one of four thousand children with severe acute respiratory syndrome coronavirus 2
Holm, M., Hartling, U. B., Schmidt, Lisbeth Samsø, Glenthøj, J. P., Kruse, A., Rytter, Maren Johanne Heilskov, Lindhard, M. S., Lawaetz, M. C., Zaharov, T., Petersen, Jens, Andersen, R. M., Lemvik, G., Marcinski, P., Thaarup, J., Jensen, Lise Heilmann, Borch, L., Nielsen, A. B., Vissing, N. H., Schmiegelow, Kjeld & Nygaard, Ulrikka, Sep 2021, In: Acta Paediatrica, International Journal of Paediatrics. 110, 9, p. 2581-2583 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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National, clinical cohort study of late effects among survivors of acute lymphoblastic leukaemia: the ALL-STAR study protocol
Andres-Jensen, L., Skipper, M. T., Mielke Christensen, K., Johnsen, P. H., Aagaard Myhr, K., Nielsen, M. K. F., Grell, Kathrine, Pedersen, Anne Marie Lynge, Rubak, S. L. M., Ballegaard, Martin, Hørlyck, A., Jensen, R. B., Lambine, T., Nielsen, K. G., Tuckuviene, R., Wehner, P. S., Albertsen, B. K., Schmiegelow, Kjeld & Frandsen, T. L., 9 Feb 2021, In: B M J Open. 11, 2, 12 p., e045543.Research output: Contribution to journal › Journal article › Research › peer-review
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No association between relapse hazard and thiopurine methyltransferase geno- or phenotypes in non-high risk acute lymphoblastic leukemia: a NOPHO ALL2008 sub-study
Nielsen, S. N., Toksvang, L. N., Grell, Kathrine, Nersting, J., Abrahamsson, J., Lund, B., Kanerva, J., Jónsson, Ó. G., Vaitkeviciene, G., Pruunsild, K., Appell, M. L., Hjalgrim, L. L. & Schmiegelow, Kjeld, 2021, In: Cancer Chemotherapy and Pharmacology. 88, p. 271–279 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pancreatitis-associated protein as an early marker of asparaginase-associated pancreatitis
Lukes, J., Wolthers, B. O., Altaf Raja, R., Uhrinova, K., Skvarova Kramarzova, K., Hermanova, I., Simcikova, M., Kicko, P., Zaliova, M., Sramkova, L., Stary, J., Trka, J., Schmiegelow, Kjeld & Starkova, J., 2021, In: Leukemia and Lymphoma. 62, 14, p. 3506-3510Research output: Contribution to journal › Letter › Research › peer-review
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Parenthood among men diagnosed with cancer in childhood and early adulthood: trends over time in a Danish national cohort
Sylvest, R., Vassard, Ditte, Schmidt, Lone, Schmiegelow, Kjeld, Macklon, K. T., Forman, Julie Lyng & Pinborg, Anja, 2021, In: Human reproduction (Oxford, England). 36, 9, p. 2576-2586 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Parenthood among men diagnosed with cancer in childhood and early adulthood - trends over time in a Danish national cohort
Sylvest, R., Vassard, Ditte, Schmiegelow, Kjeld, Macklon, K. T., Schmidt, Lone, Forman, Julie Lyng & Pinborg, Anja, Jul 2021, In: Human Reproduction. 36, p. 470-470 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Postgraduate interprofessional case-based learning in childhood cancer: A feasibility study
Topperzer, M. K., Hoffmann, M., Larsen, Hanne Bækgaard, Rosthøj, Susanne, Fridh, M. K., Roug, L. I., Andres-Jensen, L., Pontoppidan, P. E. L., Schmiegelow, Kjeld & Sorensen, Jette Led , 2021, In: Cancers. 13, 17, 4314.Research output: Contribution to journal › Journal article › Research › peer-review
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Postoperative speech impairment and surgical approach to posterior fossa tumours in children: a prospective European multicentre cohort study
Gronbaek, J. K., Wibroe, M., Toescu, S., Fric, R., Thomsen, B. L., Møller, L. N., Grillner, P., Gustavsson, B., Mallucci, C., Aquilina, K., Fellows, G. A., Molinari, E., Hjort, M. A., Westerholm-Ormio, M., Kiudeliene, R., Mudra, K., Hauser, P., van Baarsen, K., Hoving, E., Zipfel, J. & 5 others, , 2021, In: The Lancet Child and Adolescent Health. 5, 11, p. 814-824 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Prevalence of SARS-CoV-2-Antibodies in Danish Children and Adults
Rytter, Maren Johanne Heilskov, Nygaard, Ulrikka, Mandic, I. N., Glenthøj, J. P., Schmidt, Lisbeth Samsø, Cortes, Dina, Smith, Birgitte, Zaharov, T., Søndergaard, M. J., Lawaetz, M. C., Saekmose, S., Jensen, Lise Heilmann, Schmiegelow, Kjeld & Kristensen, K., 2021, In: Pediatric Infectious Disease Journal. 40, 4, p. E157-E159 3 p.Research output: Contribution to journal › Letter › Research › peer-review
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Quantification of Methotrexate in Human Serum Using Surface-Enhanced Raman Scattering—Toward Therapeutic Drug Monitoring
Göksel, Y., Zor, K., Rindzevicius, T., Thorhauge Als-Nielsen, B. E., Schmiegelow, Kjeld & Boisen, A., 2021, In: ACS Sensors. 6, 7, p. 2664-2673 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Relapse risk following truncation of PEG-asparaginase in childhood acute lymphoblastic leukemia
Gottschalk Højfeldt, S., Grell, Kathrine, Abrahamsson, J., Lund, B., Vettenranta, K., Jonsson, O. G., Frandsen, T. L., Wolthers, B. O., Marquart, Hanne Vibeke Hansen, Vaitkeviciene, G., Lepik, K., Heyman, M., Schmiegelow, Kjeld & Albertsen, B. K., 2021, In: Blood. 137, 17, p. 2373–2382Research output: Contribution to journal › Journal article › Research › peer-review
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SOHO State of the Art Updates and Next Questions: Management of Asparaginase Toxicity in Adolescents and Young Adults with Acute Lymphoblastic Leukemia
Schmiegelow, Kjeld, Rank, C. U., Stock, W., Dworkin, E. & van der Sluis, I., 2021, In: Clinical Lymphoma, Myeloma and Leukemia. 21, 11, p. 725-733Research output: Contribution to journal › Review › Research › peer-review
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Selection criteria for assembling a pediatric cancer predisposition syndrome gene panel
Byrjalsen, A., Diets, I. J., Bakhuizen, J., Hansen, Thomas van Overeem, Schmiegelow, Kjeld, Gerdes, Anne-Marie Axø, Stoltze, U., Kuiper, R. P., Merks, J. H. M., Wadt, Karin Anna Wallentin & Jongmans, M., 2021, In: Familial Cancer. 20, 4, p. 279-287 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Severe toxicity free survival: physician-derived definitions of unacceptable long-term toxicities following acute lymphocytic leukaemia
Ponte di Legno Severe Toxicity Working Group, P. D. L. S. T. W. G., Jul 2021, In: The Lancet Haematology. 8, 7, p. e513-e523 11 p.Research output: Contribution to journal › Review › Research › peer-review
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Socioeconomic position and prediagnostic health care contacts in children with cancer in Denmark: a nationwide register study
Pedersen, L. H., Erdmann, F., Aalborg, G. L., Hjalgrim, L. L., Larsen, Hanne Bækgaard, Schmiegelow, Kjeld, Winther, J. F. & Dalton, Susanne Oksbjerg, 2021, In: BMC Cancer. 21, 1104.Research output: Contribution to journal › Journal article › Research › peer-review
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The Need for Hospitalization due to SARS-CoV-2 in Children: A Population-based Estimate
Hartling, U. B., Holm, M., Glenthoej, J. P., Cortes, D., Kruse, A., Schmidt, L. S., Lindhard, M. S., Heilskov Rytter, M. J., Zaharov, T., Petersen, J. J. H., Andersen, R. M., Lemvik, G., Nissen, S. K., Marcinski, P. A., Thaarup, J., Jensen, L. H., Lawaetz, M. C., Borch, L., Vissing, N. H., Schmiegelow, K. & 1 others, , 2021, In: Pediatric Infectious Disease Journal. 40, 6, p. E250-E251 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Value of flow cytometry for MRD-based relapse prediction in B-cell precursor ALL in a multicenter setting
Modvig, S., Hallböök, H., Madsen, H. O., Siitonen, S., Rosthøj, S., Tierens, A., Juvonen, V., Osnes, L. T. N., Vålerhaugen, H., Hultdin, M., Matuzeviciene, R., Stoskus, M., Marincevic, M., Lilleorg, A., Ehinger, M., Norén-Nystrøm, U., Toft, N., Taskinen, M., Jónsson, O. G., Pruunsild, K. & 7 others, , 2021, In: Leukemia. 35, p. 1894–1906 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 8780
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Cerebellar mutism syndrome in children with brain tumours of the posterior fossa
Research output: Contribution to journal › Journal article › Research › peer-review
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300
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Genomic profiling of thousands of candidate polymorphisms predicts risk of relapse in 778 Danish and German childhood acute lymphoblastic leukemia patients
Research output: Contribution to journal › Journal article › Research › peer-review
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294
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Intermittent Versus Continuous PEG-Asparaginase to Reduce Asparaginase-Associated Toxicities: A NOPHO ALL2008 Randomized Study
Research output: Contribution to journal › Journal article › Research › peer-review
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