Hans K Hasselbalch

Hans K Hasselbalch

Clinical Professor

Member of:

  • Internal Medicine: Haematology


Publication year:
All
51 - 100 out of 133Page size: 50
  1. 2018
  2. Published

    Spontaneous T-cell responses against Arginase-1 in the chronic myeloproliferative neoplasms relative to disease stage and type of driver mutation

    Jørgensen, M. A., Holmström, M. O., Martinenaite, E., Riley, C. H., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2018, In: OncoImmunology. 7, 9, 8 p., e1468957.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Spontaneous T-cell responses against the immune check point programmed-death-ligand 1 (PD-L1) in patients with chronic myeloproliferative neoplasms correlate with disease stage and clinical response

    Holmström, M. O., Riley, C. H., Skov, V., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2018, In: OncoImmunology. 7, 6, e1433521.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The effectiveness of exercise-based rehabilitation to patients with myeloproliferative neoplasms: An explorative study

    Pedersen, K. M., Zangger, G., Brochmann, N., Grønfeldt, B. M., Zwisler, A. D., Hasselbalch, Hans Carl & Tang, L. H., 2018, In: European Journal of Cancer Care. 27, 5, 10 p., e12865.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Whole Blood Gene Expression Profiling in patients undergoing colon cancer surgery identifies differential expression of genes involved in immune surveillance, inflammation and carcinogenesis

    Watt, S. K., Hasselbalch, Hans Carl, Skov, V., Kjær, L., Thomassen, M., Kruse, T. A., Burton, M. & Gögenur, Ismail, 2018, In: Surgical Oncology. 27, 2, p. 208-215 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The calreticulin (CALR) exon 9 mutations are promising targets for cancer immune therapy

    Holmstrom, M. O., Martinenaite, E., Ahmad, S. M., Met, Özcan, Friese, C., Kjaer, L., Riley, C. H., Straten, P. T., Svane, Inge Marie, Hasselbalch, Hans Carl & Andersen, Mads Hald, 1 Feb 2018, In: Leukemia. 32, 2, p. 429-437

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Sorted peripheral blood cells identify CALR mutations in B- and T-lymphocytes

    Kjaer, L., Holmström, M. O., Cordua, S., Andersen, Mads Hald, Svane, Inge Marie, Thomassen, M., Kruse, T. A., Pallisgaard, N., Skov, V. & Hasselbalch, Hans Carl, Apr 2018, In: Leukemia and Lymphoma. 59, 4, p. 973-977 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Safety and efficacy of combination therapy of interferon-α2 and ruxolitinib in polycythemia vera and myelofibrosis

    Mikkelsen, Stine Ulrik, Kjaer, L., Bjørn, M. E., Knudsen, T. A., Sørensen, A. L., Andersen, Christen Bertel L, Bjerrum, O. W., Brochmann, N., Fassi, Daniel El , Kruse, T. A., Larsen, T. S., Mourits-Andersen, H. T., Nielsen, Claus Henrik, Pallisgaard, N., Thomassen, M., Skov, V. & Hasselbalch, Hans Carl, Aug 2018, In: Cancer Medicine. 7, 8, p. 3571-3581 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. 2019
  10. Published

    Anxiety and depression in patients with Philadelphia-negative myeloproliferative neoplasms: a nationwide population-based survey in Denmark

    Brochmann, N., Flachs, E. M., Christensen, A. I., Bak, M., Andersen, Christen Bertel L, Juel, K., Hasselbalch, Hans Carl, Zwisler, A. & Rottmann, N., 2019, In: Clinical Epidemiology. 11, p. 23-33

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Association of the blood eosinophil count with end-organ symptoms

    Bjerrum, O. W., Siersma, Volkert Dirk, Hasselbalch, Hans Carl, Lind, B. & Andersen, Christen Bertel L, 2019, In: Annals of Medicine and Surgery. 45, p. 11-18

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Bridging blood cancers and inflammation: The reduced Cancitis model

    Ottesen, J. T., Pedersen, R. K., Sajid, Z., Gudmand-hoeyer, J., Bangsgaard, K. O., Skov, V., Kjær, L., Knudsen, T. A., Pallisgaard, N., Hasselbalch, Hans Carl & Andersen, M., 2019, In: Journal of Theoretical Biology. 465, p. 90-108

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Cancer immune therapy for myeloid malignancies: present and future

    Holmström, M. O. & Hasselbalch, Hans Carl, 2019, In: Seminars in Immunopathology. 41, 1, p. 97-109

    Research output: Contribution to journal › Review › Research › peer-review

  14. Published

    Cancerimmunterapi til behandling af hæmatologisk cancer

    Holmström, M. O., Klausen, U., Jørgensen, N. G., Holmberg, S., Grauslund, J., Met, Ö., Svane, Inge Marie, Pedersen, Lars Møller, Knudsen, L. M., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2019, In: Ugeskrift for Laeger. 181, 10, 5 p., V06180421.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Cardiovascular disease in chronic myelomonocytic leukemia: do monocytosis and chronic inflammation predispose to accelerated atherosclerosis?

    Elbæk, M. V., Sørensen, A. L. & Hasselbalch, Hans Carl, 2019, In: Annals of Hematology. 98, 1, p. 101-109

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Effect of thrombopoietin receptor agonists on markers of coagulation and P-selectin in patients with immune thrombocytopenia

    Garabet, L., Ghanima, W., Monceyron Jonassen, C., Skov, V., Holst, R., Mowinckel, M., Hasselbalch, Hans Carl, A. Kruse, T., Thomassen, M., Liebman, H., Bussel, J. B. & Sandset, P. M., 2019, In: Platelets. 30, 2, p. 206-212

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Inflammatory functional iron deficiency common in myelofibrosis, contributes to anaemia and impairs quality of life. From the Nordic MPN study Group

    Birgegard, G., Samuelsson, J., Ahlstrand, E., Ejerblad, E., Enevold, C., Ghanima, W., Hasselbalch, Hans Carl, Nielsen, Claus Henrik, Knutsen, H., Pedersen, Ole Birger Vesterager, Sørensen, A. & Andreasson, B., 2019, In: European Journal of Haematology. 102, 3, p. 235-240

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    JAK2V617F but not CALR mutations confer increased molecular responses to interferon-α via JAK1/STAT1 activation

    Czech, J., Cordua, S., Weinbergerova, B., Baumeister, J., Crepcia, A., Han, L., Maié, T., Costa, I. G., Denecke, B., Maurer, A., Schubert, C., Feldberg, K., Gezer, D., Brümmendorf, T. H., Müller-newen, G., Mayer, J., Racil, Z., Kubesova, B., Knudsen, T., Sørensen, A. L. & 7 others, Holmström, M., Kjær, L., Skov, V., Larsen, T. S., Hasselbalch, Hans Carl, Chatain, N. & Koschmieder, S., 2019, In: Leukemia. 33, 4, p. 995-1010

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Methylation age as a correlate for allele burden, disease status, and clinical response in myeloproliferative neoplasm patients treated with vorinostat

    McPherson, S., Greenfield, G., Andersen, Christen Bertel L, Grinfeld, J., Hasselbalch, Hans Carl, Nangalia, J., Mills, K. I. & McMullin, M. F., 2019, In: Experimental Hematology. 79, p. 26-34 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Neo-antigen specific memory T-cell responses in healthy individuals

    Holmström, M. O., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2019, In: OncoImmunology. 8, 7, 2 p., 1599640.

    Research output: Contribution to journal › Letter › Research › peer-review

  21. Published

    Perspectives on interferon-alpha in the treatment of polycythemia vera and related myeloproliferative neoplasms: minimal residual disease and cure?

    Hasselbalch, Hans Carl & Holmström, M. O., 2019, In: Seminars in Immunopathology. 41, 1, p. 5-19

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    Prevalence and phenotypes of JAK2 V617F and calreticulin mutations in a Danish general population

    Cordua, S., Kjaer, L., Skov, V., Pallisgaard, N., Hasselbalch, Hans Carl & Ellervik, Christina, 2019, In: Blood. 134, 5, p. 469-479

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Progression of JAK2-mutant polycythemia vera to CALR-mutant myelofibrosis severely impacts on disease phenotype and response to therapy

    Holmström, M. O., Novotny, G. W., Petersen, J., Aaboe-Jørgensen, M., Hasselbalch, Hans Carl, Andersen, Mads Hald, Nielsen, S. L., Fassi, Daniel El & Schöllkopf, C., 2019, In: Leukemia and Lymphoma. 60, 13, p. 3296-3299

    Research output: Contribution to journal › Letter › Research › peer-review

  24. Published

    Smoking and Increased White and Red Blood Cells

    Pedersen, K. M., Çolak, Y., Ellervik, Christina, Hasselbalch, Hans Carl, Bojesen, Stig Egil & Nordestgaard, Børge, 2019, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 39, 5, p. 965-977 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Statin treatment, oxidative stress and inflammation in a Danish population

    Sørensen, A. L., Hasselbalch, Hans Carl, Nielsen, C. H., Poulsen, Henrik Enghusen & Ellervik, C., 2019, In: Redox Biology. 21, 7 p., 101088.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Terapeutisk cancervaccination mod hæmatologisk cancer

    Holmström, M. O., Grauslund, J. H., Dahlager-Jørgensen, N. G., Klausen, U., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2019, In: Ugeskrift for Laeger. 181, 20A, 5 p., V04190233.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Time for revival of the red blood cell count and red cell mass in the differential diagnosis between essential thrombocythemia and polycythemia vera?

    Hasselbalch, Hans Carl, 2019, In: Haematologica. 104, 11, p. 2119-2125

    Research output: Contribution to journal › Editorial › Research

  28. Published

    Variant‐specific discrepancy when quantitating BCR‐ABL1 e13a2 and e14a2 transcripts using the Europe Against Cancer qPCR assay

    Kjaer, L., Skov, V., Andersen, M. T., Aggerholm, A., Clair, P., Gniot, M., Søby, K., Udby, L., Dorff, Mikkel Helleberg, Hasselbalch, Hans Carl & Pallisgaard, N., 2019, In: European Journal of Haematology. 103, 1, p. 26-34

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Vascular diseases in patients with chronic myeloproliferative neoplasms: Impact of comorbidity

    Frederiksen, H., Szépligeti, S., Bak, M., Ghanima, W., Hasselbalch, Hans Carl & Christiansen, C. F., 2019, In: Clinical Epidemiology. 2019, 11, p. 955-967

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Ruxolitinib treatment reduces monocytic superoxide radical formation without affecting hydrogen peroxide formation or systemic oxidative nucleoside damage in myelofibrosis

    Bjørn, M. E., Brimnes, M. K., Gudbrandsdottir, S., Andersen, C. L., Poulsen, Henrik Enghusen, Henriksen, T., Hasselbalch, Hans Carl & Nielsen, Claus Henrik, Oct 2019, In: Leukemia and Lymphoma. 60, 10, p. 2549-2557 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2020
  32. Published

    Age-related prevalence and clinical significance of neutropenia - isolated or combined with other cytopenias: Real world data from 373 820 primary care individuals

    Palmblad, J., Siersma, Volkert Dirk, Lind, B., Bjerrum, O. W., Hasselbalch, Hans Carl & Andersen, Christen Bertel L, 2020, In: American Journal of Hematology. 95, 5, p. 521-528 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Cancer immune therapy for Philadelphia chromosome-negative chronic myeloproliferative neoplasms

    Holmström, M. O., Hasselbalch, Hans Carl & Andersen, Mads Hald, 2020, In: Cancers. 12, 7, p. 1-21 21 p., 1763.

    Research output: Contribution to journal › Review › Research › peer-review

  34. Published

    Data-driven analysis of JAK2V617F kinetics during interferon-alpha2 treatment of patients with polycythemia vera and related neoplasms

    Pedersen, R. K., Andersen, M., Knudsen, T. A., Sajid, Z., Gudmand-Hoeyer, J., Dam, M. J. B., Skov, V., Kjær, L., Ellervik, Christina, Larsen, T. S., Hansen, D., Pallisgaard, N., Hasselbalch, Hans Carl & Ottesen, J. T., 2020, In: Cancer Medicine. 9, 6, p. 2039-2051

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Evidence of immune elimination, immuno-editing and immune escape in patients with hematological cancer

    Holmström, M. O., Cordua, S., Skov, V., Kjær, L., Pallisgaard, N., Ellervik, Christina, Hasselbalch, Hans Carl & Andersen, Mads Hald, 2020, In: Cancer Immunology, Immunotherapy. 69, p. 315–324

    Research output: Contribution to journal › Review › Research › peer-review

  36. Published

    Increased oxidative stress with substantial dysregulation of genes related to oxidative stress and DNA repair after laparoscopic colon cancer surgery

    Watt, S. K., Hasselbalch, Hans Carl, Skov, V., Kjær, L., Thomassen, M., Kruse, T. A., Burton, M., Poulsen, Henrik Enghusen & Gögenur, Ismail, 2020, In: Surgical Oncology. 35, p. 71-78 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Loss-of-function polymorphism in IL6R reduces risk of JAK2V617F somatic mutation and myeloproliferative neoplasm: A Mendelian randomization study

    Pedersen, K. M., Çolak, Y., Ellervik, Christina, Hasselbalch, Hans Carl, Bojesen, Stig Egil & Nordestgaard, Børge, 2020, In: EClinicalMedicine. 21, 100280.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Myeloproliferative blood cancers as a human neuroinflammation model for development of Alzheimer's disease: evidences and perspectives

    Hasselbalch, Hans Carl, Skov, V., Kjær, L., Sørensen, Torben Lykke, Ellervik, Christina & Wienecke, Troels, 2020, In: Journal of Neuroinflammation. 17, 13 p., 248.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    Ocular Manifestations in Patients with Philadelphia-Negative Myeloproliferative Neoplasms

    Liisborg, C., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, 2020, In: Cancers. 12, 3, 14 p., 573.

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    Patients with myeloproliferative neoplasms and high levels of systemic inflammation develop age-related macular degeneration

    Liisborg, C., Krogh Nielsen, M., Hasselbalch, Hans Carl & Sørensen, Torben Lykke, 2020, In: EClinicalMedicine. 26, 8 p., 100526.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Rationaler for behandling med januskinase 1/2-hæmning af svært syge patienter med COVID-19-pneumoni

    Hasselbalch, Hans Carl, Poulsen, Anne, Skov, V., Kjær, L., Nielsen, C. H. & Poulsen, T. D., 2020, In: Ugeskrift for Laeger. 182, 25, 9 p., V04200234.

    Research output: Contribution to journal › Review › Research › peer-review

  42. Published

    Ropeginterferon Alfa-2b: Efficacy and Safety in Different Age Groups

    Gisslinger, H., Klade, C., Georgiev, P., Krochmalczyk, D., Gercheva-kyuchukova, L., Egyed, M., Rossiev, V., Dulicek, P., Illes, A., Pylypenko, H., Sivcheva, L., Mayer, J., Yablokova, V., Krejcy, K., Hasselbalch, Hans Carl, Kralovics, R. & Kiladjian, J., 2020, In: HemaSphere. 4, 6, 4 p., e485.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Ropeginterferon alfa-2b versus standard therapy for polycythaemia vera (PROUD-PV and CONTINUATION-PV): a randomised, non-inferiority, phase 3 trial and its extension study

    Gisslinger, H., Klade, C., Georgiev, P., Krochmalczyk, D., Gercheva-Kyuchukova, L., Egyed, M., Rossiev, V., Dulicek, P., Illes, A., Pylypenko, H., Sivcheva, L., Mayer, J., Yablokova, V., Krejcy, K., Grohmann-Izay, B., Hasselbalch, H. C., Kralovics, R., Kiladjian, J. J., Bauer, F., Berbec, N. & 41 others, Besses Raebel, C., Borbenyi, Z., Bumbea, H., Buxhofer-Ausch, V., Calbecka, M., Cayssials-Caylus, E., Cazzola, M., Cerna, O., Cucuianu, A., Dima, D. M., Forjan, E., Gheorghita, E., Greil, R., Hatalova, A., Hrubisko, M., Jakucs, J., Kaplan, P., Klymenko, S., Koschmieder, S., Lazaroiu, M., Lysa, T., Masliak, Z., Masszi, T., Mihaylov, G., Myasnikov, A., Platzbecker, U., Puyade, M., Rey, J., Roy, L., Schwarz, J., Skotnicki, A., Sokolova, I., Soroka-Wojtaszko, M., Starzak-Gwozdz, J., Stoeva, V., Torregrosa-Diaz, J. M., Vallova, A., Volodicheva, E., Warzocha, K., Willenbacher, E. & Wolf, D., 2020, In: The Lancet Haematology. 7, 3, p. e196-e208 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Safety and efficacy of the combination of sonidegib and ruxolitinib in myelofibrosis: A phase 1b/2 dose-finding study

    Gupta, V., Wolleschak, D., Hasselbalch, Hans Carl, Vannucchi, A. M., Koschmieder, S., Cervantes, F., Li, Y., Dong, T., Wroclawska, M., Bharathy, S. & Harrison, C., 2020, In: Blood advances. 4, 13, p. 3063-3071 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Tocilizumab and soluble interleukin-6 receptor in JAK2V617F somatic mutation and myeloproliferative neoplasm

    Pedersen, K. M., Çolak, Y., Hasselbalch, Hans Carl, Bojesen, Stig Egil & Nordestgaard, Børge, 2020, In: EClinicalMedicine. 22, 100337.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  46. Published

    Two-fold risk of pneumonia and respiratory mortality in individuals with myeloproliferative neoplasm: A population-based cohort study

    Pedersen, K. M., Çolak, Y., Hasselbalch, Hans Carl, Ellervik, Christina, Nordestgaard, Børge & Bojesen, Stig Egil, 2020, In: EClinicalMedicine. 21, 100295.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Smoking, blood cells and myeloproliferative neoplasms: meta-analysis and Mendelian randomization of 2·3 million people

    Jayasuriya, N. A., Kjaergaard, A. D., Pedersen, K. M., Sørensen, A. L., Bak, M., Larsen, M. K., Nordestgaard, Børge, Bojesen, Stig Egil, Çolak, Y., Skov, V., Kjaer, L., Tolstrup, J. S., Hasselbalch, Hans Carl & Ellervik, Christina, Apr 2020, In: British Journal of Haematology. 189, 2, p. 323-334 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. 2021
  49. Published

    Data-driven analysis of the kinetics of the JAK2V617F allele burden and blood cell counts during hydroxyurea treatment of patients with polycythemia vera, essential thrombocythemia, and primary myelofibrosis

    Dam, M. J. B., Pedersen, R. K., Knudsen, T. A., Andersen, M., Skov, V., Kjær, L., Hasselbalch, Hans Carl & Ottesen, J. T., 2021, In: European Journal of Haematology. 107, 6, p. 624-633 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Early detection of myeloproliferative neoplasms in a Danish general population study

    Cordua, S., Kjaer, L., Skov, V., Pallisgaard, N., Kefala, Maria, Gjerdrum, Lise Mette Rahbek, Hasselbalch, Hans Carl & Ellervik, Christina, 2021, In: Leukemia. 35, 9, p. 2706-2709 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Elevated levels of oxidized nucleosides in individuals with the JAK2V617F mutation from a general population study

    Sørensen, A. L., Hasselbalch, Hans Carl, Bjørn, M. E., Nielsen, C. H., Cordua, S., Skov, V., Kjær, L., Poulsen, Henrik Enghusen & Ellervik, Christina, 2021, In: Redox Biology. 41, 101895.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    New Perspectives of Interferon-alpha2 and Inflammation in Treating Philadelphia-negative Chronic Myeloproliferative Neoplasms

    Hasselbalch, Hans Carl & Silver, R. T., 2021, In: HemaSphere. 5, 12, p. 1-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Response to pegylated interferon in a COVID-19 positive male with metastatic jejunal neuroendocrine tumor treated with everolimus

    Frankel, A. E., Yip, W. C., Naik, E. & Hasselbalch, Hans Carl, 2021, In: Clinical Case Reports. 9, 6, e04218.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Response to pegylated interferon in a COVID-19–positive elderly woman with primary myelofibrosis treated with ruxolitinib

    Frankel, A. E., Reddy, R., DeSuza, K. R., Deeb, K., Carlin, A. F., Smith, D., Xie, Y., Naik, E., Silver, R. T. & Hasselbalch, Hans Carl, 2021, In: Clinical Case Reports. 9, 4, p. 2228-2235 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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ID: 2849472