Kristian Strømgaard
Professor
Biopharmaceuticals
Jagtvej 162
2100 København Ø
- Published
PDZ Domains as Drug Targets
Christensen, N. R., Čalyševa, J., Alves Fernandes, Eduardo Felipe, Lüchow, S., Clemmensen, L. S., Haugaard-Kedström, L. M. & Strømgaard, Kristian, 2019, In: Advanced Therapeutics. 2, 7, p. 1800143 1800143.Research output: Contribution to journal › Review › Research › peer-review
- Published
A high-affinity, bivalent PDZ domain inhibitor complexes PICK1 to alleviate neuropathic pain
Christensen, N. R., De Luca, M., Lever, M. B., Richner, M., Hansen, A. B., Noes-Holt, G., Jensen, K. L., Rathje, M., Jensen, D. B., Erlendsson, S., Bartling, C. R. O., Ammendrup-Johnsen, I., Pedersen, S. E., Schönauer, M., Nissen, K. B., Midtgaard, S. R., Teilum, K., Arleth, L., Sørensen, A. T., Bach, A. & 5 others, , 2020, In: EMBO Molecular Medicine. 12, 6, 25 p., e11248.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bidirectional protein–protein interactions control liquid–liquid phase separation of PSD-95 and its interaction partners
Christensen, N. R., Pedersen, Christian Parsbæk, Sereikaité, Vita, Pedersen, J. N., Vistrup-Parry, M., Sørensen, Andreas Toft, Otzen, D., Teilum, Kaare, Madsen, Kenneth Lindegaard & Strømgaard, Kristian, 2022, In: iScience. 25, 2, 26 p., 103808.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Probing the role of backbone hydrogen bonds in protein-peptide interactions by amide-to-ester mutations
Eildal, J. N. N., Hultqvist, G., Balle, T., Stuhr-Hansen, N., Padrah, S., Gianni, S., Strømgaard, Kristian & Jemth, P., 4 Sep 2013, In: Journal of the American Chemical Society. 135, 35, p. 12998-3007 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rigidified Clicked Dimeric Ligands for Studying the Dynamics of the PDZ1-2 Supramodule of PSD-95
Eildal, J. N. N., Bach, Anders, Dogan, J., Ye, F., Zhang, M., Jemth, P. & Strømgaard, Kristian, 2015, In: ChemBioChem. 16, p. 64–69 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From the selective serotonin transporter inhibitor citalopram to the selective norepinephrine transporter inhibitor talopram: Synthesis and structure-activity relationship studies
Eildal, J. N. N., Andersen, J., Kristensen, Anders Skov, Jørgensen, A. M., Bang-Andersen, B., Jørgensen, M. & Strømgaard, Kristian, 2008, In: Journal of Medicinal Chemistry. 51, 10, p. 3045-3048Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of Peptide-Based PDZ Domain Inhibitors
Essig, D. J., Balboa, J. R. & Strømgaard, Kristian, 2021, Methods in Molecular Biology. J-P. B. (ed.). Humana Press, p. 157-177 21 p. (Methods in Molecular Biology, Vol. 2256).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Targeting postsynaptic glutamate receptor scaffolding proteins PSD-95 and PICK1 for obesity treatment
Fadahunsi, N., Petersen, J. O., Metz, S., Jakobsen, A., Mathiesen, C. V., Buch-Rasmussen, A. S., Kurgan, N. K., Larsen, J. K., Andersen, R. C., Topilko, T., Svendsen, C., Apuschkin, M., Skovbjerg, G., Schmidt, J. H., Houser, G. A., Jager, S. E., Bach, A., Deshmukh, A. S., Kilpeläinen, T. O., Strømgaard, K. & 2 others, , 2024, In: Science Advances. 10, 9, 20 p., eadg2636.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effects of Lipidation on a TAT-Containing Peptide-Based Inhibitor of PSD-95
Alves Fernandes, Eduardo Felipe, Haugaard-Kedstroem, L. M. & Strømgaard, Kristian, 2020, In: Australian Journal of Chemistry. 73, 4, p. 307-311 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction partners of PSD-93 studied by X-ray crystallography and fluorescence polarization spectroscopy
Fiorentini, M., Bach, Anders, Strømgaard, Kristian, Kastrup, Jette Sandholm Jensen & Gajhede, Michael, Apr 2013, In: Acta Crystallographica. Section D: Biological Crystallography. 69, Pt 4, p. 587-94 8 p.Research output: Contribution to journal › Journal article › Research
- Published
Assessment of structurally diverse philanthotoxin analogues for inhibitory activity on ionotropic glutamate receptor subtypes: Discovery of nanomolar, nonselective, and use-dependent antagonists
Frølund, S., Bella, A., Kristensen, Anders Skov, Ziegler, H. L., Witt, M., Olsen, C. A., Strømgaard, Kristian, Franzyk, Henrik & Jaroszewski, J. W., 2010, In: Journal of Medicinal Chemistry. 53, 20, p. 7441-7451Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Electrophysiological characterization of analogues of philanthotoxin-343 on ionotropic glutamate receptors
Frølund, S. U., Ziegler, H. L., Franzyk, Henrik, Strømgaard, Kristian, Kristensen, Anders Skov & Jaroszewski, J. W., 2008.Research output: Contribution to conference › Poster › Research
- Published
Detecting protein-protein interactions in living cells: development of a bioluminescence resonance energy transfer assay to evaluate the PSD-95/NMDA receptor interaction
Gottschalk, M., Bach, Anders, Hansen, J. L., Krogsgaard-Larsen, Povl, Kristensen, Anders Skov & Strømgaard, Kristian, 2009, In: Neurochemical Research. 34, 10, p. 1729-1737Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Side-chain interactions form late and cooperatively in the binding reaction between disordered peptides and PDZ domains
Haq, S. R., Chi, C. N., Bach, Anders, Dogan, J., Engström, Å., Hultqvist, G., Karlsson, O. A., Lundström, P., Montemiglio, L. C., Strømgaard, Kristian, Gianni, S. & Jemth, P., Jan 2012, In: Journal of the American Chemical Society. 134, 1, p. 599-605Research output: Contribution to journal › Journal article › Research › peer-review
- Published
THE DEVELOPMENT AND CHARACTERIZATION OF A PEPTIDE-BASED SYNTENIN INHIBITOR - IMPLACATIONS FOR CANCER METASTASIS
Haugaard-Kedstrom, L. M., Albertsen, L., Gil, F. A., Ivarsson, Y., Strømgaard, Kristian & Kedström, L. M. H., Sep 2014, In: Journal of Peptide Science. 20, Suppl. 1, p. s39 1 p., YO11.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
A High-Affinity Peptide Ligand Targeting Syntenin Inhibits Glioblastoma
Haugaard-Kedstrom, L. M., Clemmensen, L. S., Sereikaite, V., Jin, Z., Fernandes, E. F. A., Wind, B., Abalde-Gil, F., Daberger, J., Vistrup-Parry, M., Aguilar-Morante, D., Leblanc, R., Egea-Jimenez, A. L., Albrigtsen, M., Jensen, K. E., Jensen, T. M. T., Ivarsson, Y., Vincentelli, R., Hamerlik, P., Andersen, J. H., Zimmermann, P. & 2 others, , 2021, In: Journal of Medicinal Chemistry. 64, 3, p. 1423-1434 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Targeting PSD-95 as a Novel Approach in the Treatment of Stroke
Haugaard-Kedstrom, L. M., Fernandes, E. F. A. & Strømgaard, Kristian, 2017, Neuroprotective Therapy for Stroke and Ischemic Disease . Springer, p. 157-184 28 p. (Springer Series in Translational Stroke Research).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Tight control of the APP-Mint1 interaction in regulating amyloid production
Henry, S. M., Kistler, S. A., Lagani, G. D., Bartling, Christian Reinhard Otto, Özcelik, D., Sereikaité, Vita, Strømgaard, Kristian, Beffert, U. & Ho, A., 2023, In: Brain Research. 1817, 6 p., 148496.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Energetic pathway sampling in a protein interaction domain
Hultqvist, G., Haq, S. R., Punekar, A. S., Chi, C. N., Engström, A., Bach, Anders, Strømgaard, Kristian, Selmer, M., Gianni, S. & Jemth, P., 25 Jun 2013, In: Structure. 21, 7, p. 1193-1202Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An expanded view of the protein folding landscape of PDZ domains
Hultqvist, G., Pedersen, S. W., Chi, C. N., Strømgaard, Kristian, Gianni, S. & Jemth, P., 11 May 2012, In: Biochemical and Biophysical Research Communications. 421, 3, p. 550-553 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
Terpene trilactones from Ginkgo biloba are antagonists of cortical glycine and GABA(A) receptors
Ivic, L., Sands, T. T. J., Fishkin, N., Nakanishi, K., Kriegstein, A. R. & Strømgaard, Kristian, 5 Dec 2003, In: Journal of Biological Chemistry. 278, 49, p. 49279-49285 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
Ginkgolides: selective acetylations, translactonization, and biological evaluation
Jaracz, S., Strømgaard, Kristian & Nakanishi, K., 28 Jun 2002, In: Journal of Organic Chemistry. 67, 13, p. 4623-4626 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ginkgolides and glycine receptors: a structure-activity relationship study
Jaracz, S., Nakanishi, K., Jensen, Anders A. & Strømgaard, Kristian, 2004, In: Chemistry: A European Journal. 10, 6, p. 1507-18 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stoffer fra Tempeltæet (Ginkgo biloba) som redskaber for studier af hjernens funktion
Jensen, Anders A. & Strømgaard, Kristian, 2006, In: Dansk Kemi 83. 87, 1, p. 16-18Research output: Contribution to journal › Journal article › Communication
- Published
Probing the pharmacophore of ginkgolides as glycine receptor antagonists
Jensen, Anders A., Begum, N., Vogensen, S. B., Knapp, K. M., Gundertofte, K., Dzyuba, S. V., Ishii, H., Nakanishi, K., Kristiansen, Uffe & Strømgaard, Kristian, 2007, In: Journal of Medicinal Chemistry. 50, 7, p. 1610-1617Research output: Contribution to journal › Journal article › Research › peer-review
ID: 1302559
Most downloads
-
2788
downloads
PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
Research output: Contribution to journal › Journal article › Research › peer-review
Published