Anne Tybjærg-Hansen
Clinical Professor
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High fat in blood and body and increased risk of clinically diagnosed non-alcoholic fatty liver disease in 105,981 individuals
Kyhl, L. K., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Nielsen, S. F., 2023, In: Atherosclerosis. 376, p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonfasting cholesterol and triglycerides and association with risk of myocardial infarction and total mortality: the Copenhagen City Heart Study with 31 years of follow-up
Langsted, A., Freiberg, J. J., Tybjaerg-Hansen, A., Schnohr, P., Jensen, G. B., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 1 Jul 2011, In: Journal of Internal Medicine. 270, 1, p. 65-75 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Lipoprotein(a) and familial hypercholesterolaemia - Authors' reply
Langsted, A., Kamstrup, P. R., Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Sep 2016, In: The Lancet Diabetes and Endocrinology. 4, 9, p. 730-731 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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High lipoprotein(a) as a possible cause of clinical familial hypercholesterolaemia: a prospective cohort study
Langsted, A., Kamstrup, P. R., Benn, Marianne, Tybjærg-Hansen, Anne & Nordestgaard, Børge, Jul 2016, In: The Lancet Diabetes and Endocrinology. 4, 7, p. 577-587 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PCSK9 R46L Loss-of-Function Mutation Reduces Lipoprotein(a), LDL Cholesterol, and Risk of Aortic Valve Stenosis
Langsted, A., Nordestgaard, Børge, Benn, Marianne, Tybjærg-Hansen, Anne & Kamstrup, P. R., Sep 2016, In: The Journal of clinical endocrinology and metabolism. 101, 9, p. 3281-3287 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Variation in NPC1L1 and Risk of Gallstone Disease
Lauridsen, B. K., Stender, S. & Tybjærg-Hansen, Anne, 1 Sep 2015, In: Journal of the American College of Cardiology. 66, 9, p. 1086 1 p.Research output: Contribution to journal › Letter › Research › peer-review
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Genetic variation in the cholesterol transporter NPC1L1, ischaemic vascular disease, and gallstone disease
Lauridsen, B. K., Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 1 Jul 2015, In: European Heart Journal. 36, 25, p. 1601-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Liver fat content, non-alcoholic fatty liver disease, and ischaemic heart disease: Mendelian randomization and meta-analysis of 279 013 individuals
Lauridsen, B. K., Stender, Steen, zwp671, zwp671, Kofoed, Klaus Fuglsang, Køber, Lars Valeur, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 5, p. 385-393 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Using genetic loci to understand the relationship between adiposity and psychological distress: a Mendelian Randomization study in the Copenhagen General Population Study of 53,221 adults
Lawlor, D. A., Harbord, R. M., Tybjærg-Hansen, Anne, Palmer, T. M., Zacho, J., Benn, M., Timpson, N. J., Smith, G. D., Nordestgaard, Børge & Benn, M., 2011, In: Journal of Internal Medicine. 269, 5, p. 525-37 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exploring causal associations between alcohol and coronary heart disease risk factors: findings from a Mendelian randomization study in the Copenhagen General Population Study
Lawlor, D. A., Nordestgaard, Børge, Benn, Marianne, Zuccolo, L., Tybjærg-Hansen, Anne & Davey Smith, G., 14 Mar 2013, In: European Heart Journal (Online).Research output: Contribution to journal › Journal article › Research › peer-review
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Genetically reduced soluble epoxide hydrolase activity and risk of stroke and other cardiovascular disease
Lee, J., Dahl, M., Grande, P., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2010, In: Stroke. 41, 1, p. 27-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetically Reduced Soluble Epoxide Hydrolase Activity and Risk of Stroke and Other Cardiovascular Disease
Lee, J., Dahl, Morten, Grande, P., Tybjærg-Hansen, Anne & Nordestgaard, B. G., Jan 2010, In: Stroke. 41, 1, p. 27-33Research output: Contribution to journal › Journal article › Research › peer-review
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The methylenetetrahydrofolate reductase C677T genotype and the risk of obesity in three large population-based cohorts
Lewis, S. J., Lawlor, D. A., Nordestgaard, B. G., Tybjærg-Hansen, Anne, Ebrahim, S., Zacho, J., Ness, A., Leary, S. & Smith, G. D., 2008, In: European Journal of Endocrinology. 159, 1, p. 35-40 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exome-wide association study of plasma lipids in >300,000 individuals
Liu, D. J., Peloso, G. M., Yu, H., Butterworth, A. S., Wang, X., Mahajan, A., Saleheen, D., Emdin, C., Alam, D., Alves, A. C., Amouyel, P., Angelantonio, E. DI., Arveiler, D., Assimes, T. L., Auer, P. L., Baber, U., Ballantyne, C. M., Bang, L. E., Benn, M., Bis, J. C. & 208 others, , 1 Dec 2017, In: Nature Genetics. 49, 12, p. 1758-1766 9 p.Research output: Contribution to journal › Letter › Research › peer-review
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Genetically elevated apolipoprotein A-I, high-density lipoprotein cholesterol levels, and risk of ischemic heart disease
Lundegaard, C., Tybjærg-Hansen, Anne, Grande, P. & Frikke-Schmidt, Ruth, 1 Dec 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 12, p. E500-10Research output: Contribution to journal › Journal article › Research › peer-review
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Neutrophil counts and cardiovascular disease
Luo, J., Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 47, p. 4953-4964 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reply to “Mendelian randomization highlights causal association between genetically increased C-reactive protein levels and reduced Alzheimer's disease risk”
Luo, J., Thomassen, J. Q., Hegazy, S. H., Rasmussen, I. J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Alzheimer's & Dementia. 18, 10, p. 2007-2009 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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Blood Leukocyte Counts in Alzheimer Disease
Luo, J., Thomassen, J. Q., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: JAMA network open. 5, 10, 14 p., E2235648.Research output: Contribution to journal › Journal article › Research › peer-review
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Validated context-dependent associations of coronary heart disease risk with genotype variation in the chromosome 9p21 region: the Atherosclerosis Risk in Communities study
Lusk, C. M., Dyson, G., Clark, A. G., Ballantyne, C. M., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Boerwinkle, E. & Sing, C. F., Sep 2014, In: Human Genetics. 133, 9, p. 1105-1116 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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U-shaped relationship of HDL and risk of infectious disease: two prospective population-based cohort studies
Madsen, C. M., Varbo, A., Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth & Nordestgaard, Børge, 2018, In: European Heart Journal. 39, 14, p. 1181-1190 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Refining the accuracy of validated target identification through coding variant fine-mapping in type 2 diabetes
Mahajan, A., Wessel, J., Willems, S. M., Zhao, W., Robertson, N. R., Chu, A. Y., Gan, W., Kitajima, H., Taliun, D., Rayner, N. W., Guo, X., Lu, Y., Li, M., Jensen, R. A., Hu, Y., Huo, S., Lohman, K. K., Zhang, W., Cook, J. P., Prins, B. P. & 32 others, , Apr 2018, In: Nature Genetics. 50, 4, p. 559-571 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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AT1 mutations and risk of atrial fibrillation based on genotypes from 71,000 individuals from the general population
Marott, S. C. W., Nordestgaard, Børge, Jensen, G. B., Tybjærg-Hansen, Anne & Benn, M., 2013, In: British Journal of Clinical Pharmacology. p. Epub ahead of printResearch output: Contribution to journal › Journal article › Research › peer-review
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Does elevated C-reactive protein increase atrial fibrillation risk? A Mendelian randomization of 47,000 individuals from the general population
Marott, S. C. W., Nordestgaard, Børge, Zacho, J., Friberg, Jens Birkedal, Jensen, G. B., Tybjærg-Hansen, Anne, Benn, Marianne & Benn, M., 31 Aug 2010, In: Journal of the American College of Cardiology. 56, 10, p. 789-95 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Causal Associations in Type 2 Diabetes Development
Marott, S. C. W., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, Marianne, 2019, In: The Journal of clinical endocrinology and metabolism. 104, 4, p. 1313-1324Research output: Contribution to journal › Journal article › Research › peer-review
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YKL-40 levels and atrial fibrillation in the general population
Marott, S. C. W., Benn, M., Johansen, J. S., Jensen, G. B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2013, In: International Journal of Cardiology.Research output: Contribution to journal › Journal article › Research › peer-review
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Components of the Metabolic Syndrome and Risk of Type 2 Diabetes
Marott, S. C. W., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, Marianne, Aug 2016, In: The Journal of clinical endocrinology and metabolism. 101, 8, p. 3212-3221 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rare and low-frequency coding variants alter human adult height
Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G., Justice, A. E., Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T., Karaderi, T. & 31 others, , 9 Feb 2017, In: Nature. 542, 7640, p. 186-190 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Autosomal recessive hypercholesterolemia in a kindred of Syrian ancestry
Martinsen, M. H., Klausen, I. C., Tybjærg-Hansen, Anne & Hedegaard, B. S., 2020, In: Journal of Clinical Lipidology. 14, 4, p. 419-424Research output: Contribution to journal › Journal article › Research › peer-review
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Genetics of Coronary Artery Disease
McPherson, R. & Tybjærg-Hansen, Anne, 18 Feb 2016, In: Circulation Research. 118, 4, p. 564-578 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Stroke genetics informs drug discovery and risk prediction across ancestries
Mishra, A., Malik, R., Hachiya, T., Jürgenson, T., Namba, S., Posner, D. C., Kamanu, F. K., Koido, M., Le Grand, Q., Shi, M., He, Y., Georgakis, M. K., Caro, I., Krebs, K., Liaw, Y. C., Vaura, F. C., Lin, K., Winsvold, B. S., Srinivasasainagendra, V., Parodi, L. & 45 others, , 2022, In: Nature. 611, 7934, p. 115-123 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Statin Eligibility for Primary Prevention of Cardiovascular Disease According to 2021 European Prevention Guidelines Compared with Other International Guidelines
Mortensen, M. B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2022, In: JAMA Cardiology. 7, 8, p. 836-843Research output: Contribution to journal › Journal article › Research › peer-review
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Using Polygenic Hazard Scores to Predict Age at Onset of Alzheimer's Disease in Nordic Populations
Motazedi, E., Cheng, W., Thomassen, J. Q., Frei, O., Rongve, A., Athanasiu, L., Bahrami, S., Shadrin, A., Ulstein, I., Stordal, E., Brækhus, A., Saltvedt, I., Sando, S. B., O'Connell, K. S., Hindley, G., Van Der Meer, D., Bergh, S., Nordestgaard, B. G., Tybjærg-Hansen, A., Brthen, G. & 10 others, , 2022, In: Journal of Alzheimer's Disease. 88, 4, p. 1533-1544Research output: Contribution to journal › Journal article › Research › peer-review
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Association Between Chromosome 9p21 Variants and the Ankle-Brachial Index Identified by a Meta-Analysis of 21 Genome-Wide Association Studies
Murabito, J. M., White, C. C., Kavousi, M., Sun, H. Y., Feitosa, M. F., Nambi, V., Lamina, C., Schillert, A., Coassin, S., Bis, J. C., Broer, L., Crawford, D. C., Franceschini, N., Frikke-Schmidt, R., Haun, M., Holewijn, S., Huffman, J. E., Hwang, S-J., Kiechl, S., Kollerits, B. & 109 others, , 2012, In: Circulation: Cardiovascular Genetics. 5, p. 100-112Research output: Contribution to journal › Journal article › Research › peer-review
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Serum soluble CD163 predicts risk of type 2 diabetes in the general population
Møller, H. J., Frikke-Schmidt, Ruth, Moestrup, S., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 1 Feb 2011, In: Clinical Chemistry. 57, 2, p. 291-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Significance of lipids, lipoproteins, and apolipoproteins during the first 14–16 months of life
Nielsen, S. T., Lytsen, R. M., Strandkjær, N., Rasmussen, I. J., Sillesen, A. S., B. Vøgg, R. O., Raja, A. A., Nordestgaard, Børge, Kamstrup, P. R., Iversen, Kasper, Bundgård, Henning, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Heart Journal. 44, 42, p. 4408-4418 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Coffee intake protects against symptomatic gallstone disease in the general population: a Mendelian randomization study
Nordestgaard, A. T., Stender, Stefan, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2020, In: Journal of Internal Medicine. 287, 1, p. 42-53Research output: Contribution to journal › Journal article › Research › peer-review
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Triglycerider målt hos ikkefastende og risiko for myokardieinfarkt, iskaemisk hjertesygdom og død blandt kvinder og maend--sekundaerpublikation
Nordestgaard, Børge, Benn, M., Schnohr, P. & Tybjærg-Hansen, Anne, 2007, In: Ugeskrift for Laeger. 169, 45, p. 3865-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Familial hypercholesterolaemia is underdiagnosed and undertreated in the general population: guidance for clinicians to prevent coronary heart disease Consensus Statement of the European Atherosclerosis Society
Nordestgaard, B. G., Chapman, M. J., Humphries, S. E., Ginsberg, H. N., Masana, L., Descamps, O. S., Wiklund, O., Hegele, R. A., Raal, F. J., Defesche, J. C., Wiegman, A., Santos, R. D., Watts, G. F., Parhofer, K. G., Hovingh, G. K., Kovanen, P. T., Boileau, C., Averna, M., Borén, J., Bruckert, E. & 9 others, , 2013, In: European Heart Journal. 34, 45, p. 3478-3490Research output: Contribution to journal › Journal article › Research › peer-review
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Lipoprotein(a) as a cardiovascular risk factor: current status
Nordestgaard, Børge, Chapman, M. J., Ray, K., Borén, J., Andreotti, F., Watts, G. F., Ginsberg, H., Amarenco, P., Catapano, A., Descamps, O. S., Fisher, E., Kovanen, P. T., Kuivenhoven, J. A., Lesnik, P., Masana, L., Reiner, Z., Taskinen, M., Tokgözoglu, L., Tybjærg-Hansen, Anne & European Atherosclerosis Society Consensus Panel, E. A. S. C. P., 1 Dec 2010, In: European Heart Journal. 31, 23, p. 2844-53 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of elevated body mass index on ischemic heart disease risk: causal estimates from a Mendelian randomisation approach
Nordestgaard, Børge, Palmer, T. M., Benn, M., Zacho, J., Tybjærg-Hansen, Anne, Davey Smith, G. & Timpson, N. J., 2012, In: P L o S Medicine. 9, 5, p. e1001212Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic determinants of LDL, lipoprotein(a), triglyceride-rich lipoproteins and HDL: concordance and discordance with cardiovascular disease risk
Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2011, In: Current Opinion in Lipidology. 22, 2, p. 113-22 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
Nordestgaard, Børge, Benn, M., Schnohr, P. & Tybjærg-Hansen, Anne, 2007, In: J A M A: The Journal of the American Medical Association. 298, 3, p. 299-308 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Advances in lipid-lowering therapy through gene-silencing technologies
Nordestgaard, Børge, Nicholls, S. J., Langsted, A., Ray, K. K. & Tybjærg-Hansen, Anne, 2018, In: Nature Reviews Cardiology. 15, p. 261-272Research output: Contribution to journal › Review › Research › peer-review
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Genetic variation in ABCA1 and risk of all-cause dementia, age-related macular degeneration, and ischemic heart disease
Nordestgaard, L. T., Christoffersen, M., Afzal, Shoaib, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2021, In: Atherosclerosis. 331, p. E38-E39 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Triglycerides as a Shared Risk Factor between Dementia and Atherosclerotic Cardiovascular Disease: A Study of 125 727 Individuals
Nordestgaard, L. T., Christoffersen, M., Afzal, Shoaib, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2021, In: Clinical Chemistry. 67, 1, p. 245-255 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cholesteryl Ester Transfer Protein Inhibitors and Access to the Retina in Age-Related Macular Degeneration-Reply
Nordestgaard, L. T., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2023, In: JAMA Cardiology. 8, 2, p. 206-207Research output: Contribution to journal › Comment/debate › Research › peer-review
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Body mass index and risk of Alzheimer's disease: A mendelian randomization study of 399,536 individuals
Nordestgaard, L. T., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Jul 2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 7, p. 2310-2320 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variation in clusterin and risk of dementia and ischemic vascular disease in the general population: Cohort studies and meta-analyses of 362,338 individuals
Nordestgaard, L. T., Tybjærg-Hansen, Anne, Rasmussen, K. L., Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: BMC Medicine. 16, 11 p., 39.Research output: Contribution to journal › Journal article › Research › peer-review
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Loss-of-function mutation in ABCA1 and risk of Alzheimer's disease and cerebrovascular disease
Nordestgaard, L. T., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Dec 2015, In: Alzheimer's & Dementia. 11, 12, p. 1430-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variants in the adenosine triphosphate-binding cassette transporter A1 and risk of age-related macular degeneration
Nordestgaard, L. T., Christoffersen, M., Afzal, Shoaib, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: European Journal of Epidemiology. 38, 9, p. 985-994 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Elevated Apolipoprotein A1 and HDL Cholesterol Associated with Age-related Macular Degeneration: 2 Population Cohorts
Nordestgaard, L. T., Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth & Nordestgaard, Børge, 16 Jun 2021, In: The Journal of clinical endocrinology and metabolism. 106, 7, p. e2749-e2758 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Long-term Benefits and Harms Associated with Genetic Cholesteryl Ester Transfer Protein Deficiency in the General Population
Nordestgaard, L. T., Christoffersen, M., Lauridsen, B. K., Afzal, Shoaib, Nordestgaard, Børge, Frikke-Schmidt, Ruth & Tybjærg-Hansen, Anne, 2022, In: JAMA Cardiology. 7, 1, p. 55-64Research output: Contribution to journal › Journal article › Research › peer-review
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Macular Degeneration and CETP Inhibition-Reply
Nordestgaard, L. T., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2022, In: JAMA Cardiology. 7, 7, p. 775-776 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
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High-throughput genotyping of copy number variation in glutathione S-transferases M1 and T1 using real-time PCR in 20,687 individuals
Norskov, M. S., Frikke-Schmidt, Ruth, Loft, Steffen & Tybjærg-Hansen, Anne, 2009, In: Clinical Biochemistry. 42, 3, p. 201-209 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glutathione S-transferases T1 and M1 and asthma risk in 10,000 individuals and in meta-analysis
Norskov, M., Dahl, Morten & Tybjærg-Hansen, Anne, 1 Sep 2013.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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Copy number variation in glutathione-S-transferase T1 and M1 predicts incidence and 5-year survival from prostate and bladder cancer, and incidence of corpus uteri cancer in the general population
Nørskov, M. S., Frikke-Schmidt, Ruth, Bojesen, Stig Egil, Nordestgaard, Børge, Loft, Steffen & Tybjærg-Hansen, Anne, 2011, In: Pharmacogenomics Journal. 11, 4, p. 292-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Copy number variation in glutathione S-transferases M1 and T1 and ischemic vascular disease: four studies and meta-analyses
Nørskov, M. S., Frikke-Schmidt, Ruth, Loft, Steffen, Sillesen, Henrik, Grande, P., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2011, In: Circulation: Cardiovascular Genetics. 4, 4, p. 418-28 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Variation in GSTP1, Lung Function, Risk of Lung Cancer, and Mortality
Nørskov, M. S., Dahl, Morten & Tybjærg-Hansen, Anne, Nov 2017, In: Journal of Thoracic Oncology. 12, 11, p. 1664-1672 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger Receptor Class B Type 1) in Humans
Oldoni, F., van Capelleveen, J. C., Dalila, N., Wolters, J. C., Heeren, J., Sinke, R. J., Hui, D. Y., Dallinga-Thie, G. M., Frikke-Schmidt, Ruth, Hovingh, K. G., van de Sluis, B., Tybjærg-Hansen, Anne & Kuivenhoven, J. A., 2018, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 38, 7, p. 1440-1453 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of plasma uric acid with ischaemic heart disease and blood pressure: mendelian randomisation analysis of two large cohorts
Palmer, T. M., Nordestgaard, Børge, Benn, Marianne, Tybjærg-Hansen, Anne, Davey Smith, G., Lawlor, D. A. & Timpson, N. J., 2013, In: B M J (Online). 347, p. 1-10 10 p., f4262.Research output: Contribution to journal › Journal article › Research › peer-review
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Equalization of four cardiovascular risk algorithms after systematic recalibration: individual-participant meta-analysis of 86 prospective studies
Pennells, L., Kaptoge, S., Wood, A., Sweeting, M., Zhao, X., White, I., Burgess, S., Willeit, P., Bolton, T., Moons, K. G. M., van der Schouw, Y. T., Selmer, R., Khaw, K-T., Gudnason, V., Assmann, G., Amouyel, P., Salomaa, V., Kivimaki, M., Nordestgaard, B. G., Blaha, M. J. & 255 others, , 2019, In: European Heart Journal. 40, 7, p. 621-631 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ANGPTL7, a therapeutic target for increased intraocular pressure and glaucoma
Praveen, K., Patel, G. C., Gurski, L., Ayer, A. H., Persaud, T., Still, M. D., Miloscio, L., Van Zyl, T., Di Gioia, S. A., Brumpton, B., Krebs, K., Åsvold, B. O., Chen, E., Chavali, V. R. M., Fury, W., Gudiseva, H. V., Hyde, S., Jorgenson, E., Lefebvre, S., Li, D. & 37 others, , 2022, In: Communications Biology . 5, 15 p., 1051.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variants in CYP7A1 and risk of myocardial infarction and symptomatic gallstone disease
Qayyum, F., Lauridsen, B. K., Frikke-Schmidt, Ruth, Kofoed, Klaus Fuglsang, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 22, p. 2106-2116 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A framework for quantifying net benefits of alternative prognostic models
Rapsomaniki, E., White, I. R., Wood, A. M., Thompson, S. G., Emerging Risk Factors Collaboration, E. R. F. C., ATH, A. & Tybjærg-Hansen, Anne, 2012, In: Statistics in Medicine. 31, 2, p. 114-30 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma apolipoprotein E levels and risk of dementia: A Mendelian randomization study of 106,562 individuals
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Jan 2018, In: Alzheimer's & Dementia. 14, 1, p. 71-80Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma levels of apolipoprotein E, APOE genotype, and all-cause and cause-specific mortality in 105949 individuals from a white general population cohort
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 1 Sep 2019, In: European Heart Journal. 40, 33, p. 2813-2824 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Mar 2016, In: Data in Brief. 6, p. 923-932 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations of Alzheimer Disease-Protective APOE Variants With Age-Related Macular Degeneration
Rasmussen, Katrine Laura, Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2023, In: JAMA Ophthalmology. 141, 1, p. 13-21 9 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Plasma levels of apolipoprotein E and risk of dementia in the general population
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Feb 2015, In: Annals of Neurology. 77, 2, p. 301-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma levels of apolipoprotein E and risk of ischemic heart disease in the general population
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Mar 2016, In: Atherosclerosis. 246, p. 63-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
APOE and dementia – resequencing and genotyping in 105,597 individuals
Rasmussen, K. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2020, In: Alzheimer's and Dementia. 16, 12, p. 1624-1637 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
APOE and vascular disease: Sequencing and genotyping in general population cohorts
Rasmussen, Katrine Laura, Luo, J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2023, In: Atherosclerosis. 385, 9 p., 117218.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Angiotensinogen and ACE gene polymorphisms and risk of atrial fibrillation in the general population.
Ravn, L. S., Benn, M., Nordestgaard, B. G., Sethi, A. A., Agerholm-Larsen, B., Jensen, G. B., Tybjaerg-Hansen, A. & Tybjærg-Hansen, Anne, 2008, In: Pharmacogenetics and Genomics. 18, 6, p. 525-33 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Angiotensinogen and ACE gene polymorphisms and risk of atrial fibrillation in the general population
Ravn, L. S., Benn, Marianne, Nordestgaard, Børge, Sethi, A. A., Agerholm-Larsen, B., Jensen, G. B. & Tybjærg-Hansen, Anne, 2008, In: Pharmacogenetics and Genomics (Print Edition). 18, 6, p. 525-533 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variants in the GPR146 Gene Are Associated With a Favorable Cardiometabolic Risk Profile
Rimbert, A., Yeung, M. W., Dalila, N., Thio, C. H. L., Yu, H., Loaiza, N., Oldoni, F., van der Graaf, A., Wang, S., Said, M. A., Blauw, L. L., Girardeau, A., Bray, L., Caillaud, A., Bloks, V. W., Marrec, M., Mouli, P., Rensen, P. C. N., van de Sluis, B., Snieder, H. & 6 others, , 2022, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 42, 10, p. 1262-1271 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A common variant in CCDC93 protects against myocardial infarction and cardiovascular mortality by regulating endosomal trafficking of low-density lipoprotein receptor
Rimbert, A., Dalila, N., Wolters, J. C., Huijkman, N., Smit, M., Kloosterhuis, N., Riemsma, M., Van Der Veen, Y., Singla, A., Van Dijk, F., Frikke-Schmidt, Ruth, Burstein, E., Tybjærg-Hansen, Anne, Van De Sluis, B. & Kuivenhoven, J. A., 2020, In: European Heart Journal. 41, 9, p. 1040-1053 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of genotype on vascular endothelial growth factor and regulation of myocardial collateral blood flow in patients with acute and chronic coronary heart disease
Ripa, R. S., Jorgensen, E., Baldazzi, F., Frikke-Schmidt, Ruth, Wang, Y., Tybjærg-Hansen, Anne & Kastrup, J., 2009, In: Scandinavian Journal of Clinical & Laboratory Investigation. 69, 6, p. 722-728 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Women, lipids, and atherosclerotic cardiovascular disease: a call to action from the European Atherosclerosis Society
Roeters Van Lennep, J. E., Tokgözoǧlu, L. S., Badimon, L., Dumanski, S. M., Gulati, M., Hess, C. N., Holven, K. B., Kavousi, M., Kaylkçloǧlu, M., Lutgens, E., Michos, E. D., Prescott, Eva, Stock, J. K., Tybjærg-Hansen, Anne, Wermer, M. J. H. & Benn, Marianne, 2023, In: European Heart Journal. 44, 39, p. 4157-4173 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Diabetes mellitus, fasting blood glucose concentration, and risk of vascular disease: a collaborative meta-analysis of 102 prospective studies
Sarwar, N., Gao, P., Seshasai, S. R. K., Gobin, R., Kaptoge, S., Di Angelantonio, E., Ingelsson, E., Lawlor, D. A., Selvin, E., Stampfer, M., Stehouwer, C. D. A., Lewington, S., Pennells, L., Thompson, A., Sattar, N., White, I. R., Ray, K. K., Danesh, J., Jørgensen, T., Emerging Risk Factors Collaboration & 3 others, , 26 Jun 2010, In: Lancet. 375, 9733, p. 2215-22 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Triglyceride-mediated pathways and coronary disease: collaborative analysis of 101 studies
Sarwar, N., Sandhu, M. S., Ricketts, S. L., Butterworth, A. S., Di Angelantonio, E., Boekholdt, S. M., Ouwehand, W., Watkins, H., Samani, N. J., Saleheen, D., Lawlor, D., Reilly, M. P., Hingorani, A. D., Talmud, P. J., Danesh, J., Jørgensen, T., Triglyceride Coronary Disease Genetics Consortium and Emerging Risk Factors Collaboration, T. C. D. G. C. A. E. R. F. C., Tybjærg-Hansen, Anne, Frikke-Schmidt, R. & Nordestgaard, Børge, 8 May 2010, In: Lancet. 375, 9726, p. 1634-9 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin-6 receptor pathways in coronary heart disease: a collaborative meta-analysis of 82 studies
Sarwar, N., Butterworth, A. S., Freitag, D. F., Gregson, J., Willeit, P., Gorman, D. N., Gao, P., Saleheen, D., Rendon, A., Nelson, C. P., Braund, P. S., Hall, A. S., Chasman, D. I., Tybjærg-Hansen, A., Chambers, J. C., Benjamin, E. J., Franks, P. W., Clarke, R., Wilde, A. A. M., Trip, M. D. & 31 others, , 31 Mar 2012, In: Lancet. 379, 9822, p. 1205-13 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ABC transporter genes and risk of type 2 diabetes: a study of 40,000 individuals from the general population
Schou, J., Tybjærg-Hansen, Anne, Møller, H. J., Nordestgaard, Børge & Frikke-Schmidt, R., 2012, In: Diabetes Care. 35, 12, p. 2600-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variation in ABCG1 and Risk of Myocardial Infarction and Ischemic Heart Disease
Schou, J., Frikke-Schmidt, R., Kardassis, D., Thymiakou, E., Nordestgaard, Børge, Jensen, G., Grande, P. & Tybjærg-Hansen, Anne, 2012, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 32, p. 506-15 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A rare genetic variant in the manganese transporter SLC30A10 and elevated liver enzymes in the general population
Seidelin, A. S., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Yaghootkar, H. & Stender, Stefan, 2022, In: Hepatology International. 16, 3, p. 702-711Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic Variation at PPP1R3B Increases Hepatic CT Attenuation and Interacts With Prandial Status on Plasma Glucose
Seidelin, A., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Stender, S., 2020, In: Journal of Clinical Endrocrinology and Metabolism. 105, 6, p. 1963–1972Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diabetes mellitus, fasting glucose, and risk of cause-specific death
Seshasai, S. R. K., Kaptoge, S., Thompson, A., Di Angelantonio, E., Gao, P., Sarwar, N., Whincup, P. H., Mukamal, K. J., Gillum, R. F., Holme, I., Njølstad, I., Fletcher, A., Nilsson, C. M. P., Lewington, S., Collins, R., Gudnason, V., Thompson, S. G., Sattar, N., Selvin, E., Hu, F. B. & 7 others, , 2011, In: New England Journal of Medicine. 364, 9, p. 829-41 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
164Ile allele in the beta2-Adrenergic receptor gene is associated with risk of elevated blood pressure in women. The Copenhagen City Heart Study
Sethi, A., Tybjærg-Hansen, A., Jensen, G. B., Nordestgaard, B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2005, In: Pharmacogenetics and Genomics. 15, 9, p. 633-45 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High pre-beta1 HDL concentrations and low lecithin: cholesterol acyltransferase activities are strong positive risk markers for ischemic heart disease and independent of HDL-cholesterol
Sethi, A. A., Sampson, M., Warnick, R., Muniz, N., Vaisman, B., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Remaley, A. T., 1 Jul 2010, In: Clinical Chemistry. 56, 7, p. 1128-37 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Age-Specific Quantitative Effects of Metabolic Risk Factors on Cardiovascular Diseases and Diabetes: A Pooled Analysis
Singh, G. M., Danaei, G., Farzadfar, F., Stevens, G. A., Woodward, M., Wormser, D., Kaptoge, S., Whitlock, G., Qiao, Q., Lewington, S., Di Angelantonio, E., Vander Hoorn, S., Lawes, C. M. M., Ali, M. K., Mozaffarian, D., Ezzati, M., Tybjærg-Hansen, Anne, Frikke-Schmidt, Ruth, Benn, Marianne & Nordestgaard, Børge, Jul 2013, In: P L o S One. 8, 7, p. 1-10 10 p., e65174.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Strengthening the Reporting of Observational Studies in Epidemiology Using Mendelian Randomization: The STROBE-MR Statement
Skrivankova, V. W., Richmond, R. C., Woolf, B. A. R., Yarmolinsky, J., Davies, N. M., Swanson, S. A., Vanderweele, T. J., Higgins, J. P. T., Timpson, N. J., Dimou, N., Langenberg, C., Golub, R. M., Loder, E. W., Gallo, V., Tybjærg-Hansen, Anne, Davey Smith, G., Egger, M. & Richards, J. B., 2021, In: JAMA - Journal of the American Medical Association. 326, 16, p. 1614-1621Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of allele-specific FAIRE to determine functional regulatory polymorphism using large-scale genotyping arrays
Smith, F. A., Howard, P., Shah, S., Eriksson, P., Stender, S., Giambartolomei, C., Folkersen, L. W., Tybjærg-Hansen, Anne, Kumari, M., Palmen, J., Hingorani, A. D., Talmud, P. J. & Humphries, S. E., 2012, In: P L o S Genetics. 8, 8, p. e1002908Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipoprotein distribution and serum concentrations of 7α-hydroxy-4-cholesten-3-one and bile acids: effects of monogenic disturbances in high-density lipoprotein metabolism
Steiner, C., Holleboom, A. G., Karuna, R., Motazacker, M. M., Kuivenhoven, J. A., Frikke-Schmidt, R., Tybjærg-Hansen, Anne, Rohrer, L., Rentsch, K. M. & von Eckardstein, A., 2012, In: Clinical Science. 122, 8, p. 385-96 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation in liver x receptor alpha and risk of ischemic vascular disease in the general population
Stender, S., Frikke-Schmidt, R., Anestis, A., Kardassis, D., Sethi, A. A., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2011, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 31, 12, p. 2990-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Extreme Bilirubin Levels as a Causal Risk Factor for Symptomatic Gallstone Disease
Stender, Stefan, Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2013, In: Annals of Internal Medicine. 173, 13, p. 1222-1228 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci
Stender, S., Kozlitina, J., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Hobbs, H. H. & Cohen, J. C., Jun 2017, In: Nature Genetics. 49, 6, p. 842-847 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationship between genetic variation at PPP1R3B and levels of liver glycogen and triglyceride
Stender, S., Smagris, E., Lauridsen, B. K., Kofoed, Klaus Fuglsang, Nordestgaard, Børge, Tybjærg-Hansen, Anne, Pennacchio, L. A., Dickel, D. E., Cohen, J. C. & Hobbs, H. H., 2018, In: Hepatology. 67, 6, p. 2182-2195 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ABCG5/8 Cholesterol Transporter and Myocardial Infarction Versus Gallstone Disease
Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2014, In: Journal of the American College of Cardiology. 63, 20, p. 2121-2128 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetically elevated bilirubin and risk of ischaemic heart disease: three Mendelian randomization studies and a meta-analysis
Stender, S., Frikke-Schmidt, R., Nordestgaard, Børge, Grande, P. & Tybjærg-Hansen, Anne, 2013, In: The Internet Journal of Internal Medicine. 273, 1, p. 59-68 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to: liver fat content, non-alcoholic fatty liver disease, and ischaemic heart disease
Stender, S. & Tybjærg-Hansen, Anne, 2018, In: European Heart Journal. 39, 36, p. 3399Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Elevated body mass index as a causal risk factor for symptomatic gallstone disease: A Mendelian randomization study
Stender, Stefan, Nordestgaard, B. G. & Tybjærg-Hansen, Anne, 2013, In: Hepatology. 58, 6, p. 2133–2141Research output: Contribution to journal › Journal article › Research › peer-review
ID: 924951
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ABCA7 and risk of dementia and vascular disease in the Danish population
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The UK10K project identifies rare variants in health and disease
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Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease
Research output: Contribution to journal › Journal article › Research › peer-review
Published