Anne Tybjærg-Hansen
Clinical Professor
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Total and cause-specific mortality by elevated transferrin saturation and hemochromatosis genotype in individuals with diabetes - two general population studies
Ellervik, Christina, Mandrup-Poulsen, Thomas, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 15 Oct 2013, In: Diabetes Care. 37, 2, p. 444-452 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Total mortality by transferrin saturation levels: two general population studies and a metaanalysis
Ellervik, Christina, Tybjærg-Hansen, Anne, Nordestgaard, Børge, Ellervik, Christina, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2011, In: Clinical Chemistry. 57, 3, p. 459-66 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Total mortality by elevated transferrin saturation in patients with diabetes
Ellervik, Christina, Andersen, H. U., Tybjærg-Hansen, Anne, Frandsen, M. M., Birgens, H., Nordestgaard, Børge & Mandrup-Poulsen, Thomas, Sep 2013, In: Diabetes Care. 36, 9, p. 2646-54 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Elevated transferrin saturation and risk of diabetes: Three population-based studies
Ellervik, Christina, Mandrup-Poulsen, Thomas, Andersen, H. U., Tybjærg-Hansen, Anne, Frandsen, M., Birgens, H. & Nordestgaard, Børge, 2011, In: Diabetes Care. 34, 10, p. 2256-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Elevated transferrin saturation and risk of diabetes: three population-based studies
Ellervik, Christina, Mandrup-Poulsen, T., Andersen, H. U., Tybjærg-Hansen, Anne, Frandsen, M. M., Birgens, H. & Nordestgaard, Børge, 2011, In: Diabetes Care. 34, 10, p. 2256-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Total and cause-specific mortality by moderately and markedly increased ferritin concentrations: general population study and metaanalysis
Ellervik, Christina, Marott, J. L., Tybjærg-Hansen, Anne, Schnohr, P. & Nordestgaard, Børge, Nov 2014, In: Clinical Chemistry. 60, 11, p. 1419-1428 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of LDL Cholesterol on Microvascular Versus Macrovascular Disease: A Mendelian Randomization Study
Emanuelsson, F., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, Marianne, Sep 2019, In: Journal of the American College of Cardiology. 74, 11, p. 1465-1476Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of Glucose Level on Micro- and Macrovascular Disease in the General Population: A Mendelian Randomization Study
Emanuelsson, F., Marott, S., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Benn, Marianne, Apr 2020, In: Diabetes Care. 43, 4, p. 894-902 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Methylenetetrahydrofolate reductase polymorphism (C677T), hyperhomocysteinemia, and risk of ischemic cardiovascular disease and venous thromboembolism: prospective and case-control studies from the Copenhagen City Heart Study
Frederiksen, J., Juul, K., Grande, P., Jensen, G. B., Schroeder, T. V., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 15 Nov 2004, In: Blood. 104, 10, p. 3046-51 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Novel mutations in leukotriene C4 synthase and risk of cardiovascular disease based on genotypes from 50,000 individuals
Freiberg, J. J., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 1 Aug 2010, In: Journal of Thrombosis and Haemostasis. 8, 8, p. 1694-701 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Promotor polymorphisms in leukotriene C4 synthase and risk of ischemic cerebrovascular disease.
Freiberg, J. J., Tybjærg-Hansen, Anne, Sillesen, Henrik, Jensen, G. B., Nordestgaard, Børge, Freiberg, J. J., Tybjærg-Hansen, Anne, Sillesen, H., Jensen, G. B. & Nordestgaard, B. G., 2008, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 5, p. 990-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Triglycerides, depression, and risk of ischemic stroke
Freiberg, J. J., Tybjærg-Hansen, Anne & Nordestgaard, B. G., 2009, In: JAMA - Journal of the American Medical Association. 301, p. 1338-1339 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Nonfasting Triglycerides and Risk of Ischemic Stroke in the General Population
Freiberg, J. J., Tybjærg-Hansen, Anne, Jensen, J. S. & Nordestgaard, B. G., 2008, In: JAMA - Journal of the American Medical Association. 300, 18, p. 2142-2152 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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[Nonfasting triglycerides and risk of ischemic stroke--secondary publication]
Freiberg, J. J., Tybjærg-Hansen, Anne, Jensen, J. S. & Nordestgaard, B. G., 2009, In: Ugeskrift for læger. 171, 26, p. 2188-2191 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ikkefastende triglycerider og risiko for iskæmisk apopleksi - sekundærpublikation
Freiberg, J., Tybjærg-Hansen, Anne, Jensen, J. S. & Nordestgaard, Børge, 2009, In: Ugeskrift for læger. 171, p. 2188-2191Research output: Contribution to journal › Journal article › Research › peer-review
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Leukotriene C4 synthase and ischemic cardiovascular disease and obstructive pulmonary disease in 13,000 individuals
Freiberg, J. J., Dahl, M., Tybjærg-Hansen, Anne, Grande, P. & Nordestgaard, B. G., 2009, In: Journal of Molecular and Cellular Cardiology. 46, 4, p. 579-86 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Ikkefastende triglycerider og risiko for iskamisk apopleksi--sekundaerpublikation
Freiberg, J. J., Tybjærg-Hansen, Anne, Jensen, J. S. & Nordestgaard, B. G., 2009, In: Ugeskrift for læger. 171, 26, p. 2188-91 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Leukotriene C-4 synthase and ischemic cardiovascular disease and obstructive pulmonary disease in 13,000 individuals
Freiberg, J. J., Dahl, Morten, Tybjærg-Hansen, Anne, Grande, P. & Nordestgaard, B. G., Apr 2009, In: Journal of Molecular and Cellular Cardiology. 46, 4, p. 579-586Research output: Contribution to journal › Journal article › Research › peer-review
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Functional promoter variant in zinc finger protein 202 predicts severe atherosclerosis and ischemic heart disease
Frikke-Schmidt, Ruth, Nordestgaard, Børge, Grande, P., Tybjærg-Hansen, Anne & Schnohr, P., 2008, In: Journal of the American College of Cardiology. 52, 5, p. 369-377 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Subgroups at high risk for ischaemic heart disease:identification and validation in 67 000 individuals from the general population
Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Dyson, G., Haase, C. L., Benn, Marianne, Nordestgaard, Børge & Sing, C. F., 2015, In: International Journal of Epidemiology. 44, 1, p. 117-128 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Common clinical practice versus new PRIM score in predicting coronary heart disease risk
Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Schnohr, P., Jensen, G. B. & Nordestgaard, Børge, 1 Dec 2010, In: Atherosclerosis. 213, 2, p. 532-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Observational and genetic studies of C-reactive protein levels and risk of Alzheimer's disease
Frikke-Schmidt, Ruth, Hegazy, S. H., Rasmussen, I. J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Thomassen, J. Q., 2022, In: Alzheimer's and Dementia. 18, 12, p. 2734-2735Research output: Contribution to journal › Comment/debate › Research › peer-review
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Genetic variation in ABCA1 predicts ischemic heart disease in the general population
Frikke-Schmidt, Ruth, Nordestgaard, B., Jensen, G. B., Steffensen, R., Tybjaerg-Hansen, A., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Frikke-Schmidt, R. & Steffensen, R., 2008, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 28, 1, p. 180-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic variation in ABC transporter A1 contributes to HDL cholesterol in the general population
Frikke-Schmidt, R., Nordestgaard, Børge, Jensen, G. B. & Tybjærg-Hansen, Anne, 2004, In: Journal of Clinical Investigation. 114, 9, p. 1343-53 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Residual vascular risk in diabetes: Will the SPPARM alpha concept hold the key?
Fruchart, J. C., Santos, R. D., Yamashita, S., Libby, P., International Atherosclerosis Society/R3i Foundation Consensus Panel, I. A. S. F. C. P., Fruchart, J., Santos, R. D., Yamashita, S., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Watts, G. F., Yokote, K. & Zambon, A., 2019, In: Diabetes and Metabolic Syndrome: Clinical Research and Reviews. 13, 4, p. 2723-2725Research output: Contribution to journal › Review › Research › peer-review
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The selective peroxisome proliferator-activated receptor alpha modulator (SPPARMα) paradigm: conceptual framework and therapeutic potential : A consensus statement from the International Atherosclerosis Society (IAS) and the Residual Risk Reduction Initiative (R3i) Foundation
Fruchart, J-C., Santos, R. D., Aguilar-Salinas, C., Aikawa, M., Al Rasadi, K., Amarenco, P., Barter, P. J., Ceska, R., Corsini, A., Després, J-P., Duriez, P., Eckel, R. H., Ezhov, M. V., Farnier, M., Ginsberg, H. N., Hermans, M. P., Ishibashi, S., Karpe, F., Kodama, T., Koenig, W. & 35 others, , 2019, In: Cardiovascular Diabetology. 18, 20 p., 71.Research output: Contribution to journal › Review › Research › peer-review
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Mild-to-Moderate Kidney Dysfunction and Cardiovascular Disease: Observational and Mendelian Randomization Analyses
Gaziano, L., Sun, L., Arnold, M., Bell, S., Cho, K., Kaptoge, S. K., Song, R. J., Burgess, S., Posner, D. C., Mosconi, K., Robinson-Cohen, C., Mason, A. M., Bolton, T. R., Tao, R., Allara, E., Schubert, P., Chen, L., Staley, J. R., Staplin, N., Altay, S. & 30 others, , 2022, In: Circulation. 146, 20, p. 1507-1517 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic risk of fatty liver disease and mortality in the general population: A Mendelian randomization study
Gellert-Kristensen, H., Tybjærg-Hansen, Anne, Nordestgaard, Børge, Ghouse, Jonas, Fuchs, A., Kühl, J. T., Sigvardsen, P. E., Kofoed, Klaus Fuglsang & Stender, S., 2023, In: Liver International. 43, 9, p. 1955-1965 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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High Risk of Fatty Liver Disease Amplifies the Alanine Transaminase–Lowering Effect of a HSD17B13 Variant
Gellert-Kristensen, H., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Stender, S., 2020, In: Hepatology. 71, 1, p. 56-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Combined Effect of PNPLA3, TM6SF2, and HSD17B13 Variants on Risk of Cirrhosis and Hepatocellular Carcinoma in the General Population
Gellert-Kristensen, H., Richardson, T. G., Davey Smith, G., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Stender, Steen, 2020, In: Hepatology. 72, 3, p. 845-856Research output: Contribution to journal › Journal article › Research › peer-review
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Identification and Replication of Six Loci Associated With Gallstone Disease
Gellert-Kristensen, H., Dalila, N., Fallgaard Nielsen, S., Grønne Nordestgaard, B., Tybjærg-Hansen, Anne & Stender, S., Aug 2019, In: Hepatology. 70, 2, p. 597-609 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Integrative common and rare variant analyses provide insights into the genetic architecture of liver cirrhosis
Ghouse, J., Sveinbjörnsson, G., Vujkovic, M., Seidelin, A-S., Gellert-Kristensen, H., Ahlberg, G., Tragante, V., Rand, S. A., Brancale, J., Vilarinho, S., Lundegaard, P. R., Sørensen, E., Erikstrup, C., Bruun, M. T., Jensen, B. A., Brunak, S., Banasik, K., Ullum, H., Verweij, N., Lotta, L. & 31 others, , 2024, In: Nature Genetics. 56, p. 827–837 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Triglyceride-rich lipoproteins and their remnants: Metabolic insights, role in atherosclerotic cardiovascular disease, and emerging therapeutic strategies - a consensus statement from the European Atherosclerosis Society
Ginsberg, H. N., Packard, C. J., Chapman, M. J., Borén, J., Aguilar-Salinas, C. A., Averna, M., Ference, B. A., Gaudet, D., Hegele, R. A., Kersten, S., Lewis, G. F., Lichtenstein, A. H., Moulin, P., Nordestgaard, B. G., Remaley, A. T., Staels, B., Stroes, E. S. G., Taskinen, M-R., Tokgözoğlu, L. S., Tybjaerg-Hansen, A. & 2 others, , 2021, In: European Heart Journal. 42, 47, p. 4791-4806 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Medullary thyroid cancer: RET testing of an archival material
Godballe, C., Jørgensen, G., Gerdes, Anne-Marie Axø, Krogdahl, A. S., Tybjærg-Hansen, Anne & Nielsen, Finn Cilius, 1 Apr 2010, In: European Archives of Oto-Rhino-Laryngology. 267, 4, p. 613-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Association of Low Plasma Transthyretin Concentration with Risk of Heart Failure in the General Population
Greve, A. M., Christoffersen, M., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2021, In: JAMA Cardiology. 6, 3, p. 258-266Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes
Gusarova, V., O'Dushlaine, C., Teslovich, T. M., Benotti, P. N., Mirshahi, T., Gottesman, O., Van Hout, C. V., Murray, M. F., Mahajan, A., Nielsen, J. B., Fritsche, L., Wulff, A. B., Gudbjartsson, D. F., Sjögren, M., Emdin, C. A., Scott, R. A., Lee, W. J., Small, A., Kwee, L. C., Dwivedi, O. P. & 61 others, , 2018, In: Nature Communications. 9, 1, 2252.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutation in APOA1 predicts increased risk of ischaemic heart disease and total mortality without low HDL cholesterol levels
Haase, C. L., Frikke-Schmidt, Ruth, Nordestgaard, Børge, Kateifides, A. K., Kardassis, D., Nielsen, L. B., Andersen, C. B., Køber, Lars Valeur, Johnsen, A. H., Grande, P., Zannis, V. I. & Tybjærg-Hansen, Anne, 2011, In: Journal of Internal Medicine. 270, 2, p. 136-46 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Mutation in APOA1 predicts increased risk of ischaemic heart disease and mortality without low HDL cholesterol
Haase, C. L., Frikke-Schmidt, Ruth, Nordestgaard, Børge, Kateifides, A. K., Kardassis, D., Nielsen, L. B., Johnsen, A. H., Grande, P., Zannis, V. I., Tybjaerg-Hansen, A., Johnsen, A. H. & Tybjærg-Hansen, Anne, 2010, In: Amyloid: the Journal of Protein Folding Disorders. 17, p. 129 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Common Genetic Variation in Apoa1 Contributes to Elevated Hdl Cholesterol in the General Population
Haase, C. L., Frikke-Schmidt, Ruth, Nordestgaard, Børge, Jensen, G., Tybjaerg-Hansen, A. & Tybjærg-Hansen, Anne, 2010, In: Atherosclerosis. Supplement. 11, 2, p. 90 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Population-Based Resequencing of APOA1 in 10,330 Individuals: Spectrum of Genetic Variation, Phenotype, and Comparison with Extreme Phenotype Approach
Haase, C. L., Frikke-Schmidt, R., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2012, In: P L o S Genetics. 8, 11, p. e1003063Research output: Contribution to journal › Journal article › Research › peer-review
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HDL Cholesterol and Risk of Type 2 Diabetes: A Mendelian Randomization Study
Haase, C. L., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, Sep 2015, In: Diabetes. 64, 9, p. 3328-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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LCAT, HDL Cholesterol and Ischemic Cardiovascular Disease: A Mendelian Randomization Study of HDL Cholesterol in 54,500 Individuals
Haase, C. L., Tybjærg-Hansen, Anne, Ali Qayyum, A., Schou, J., Nordestgaard, Børge & Frikke-Schmidt, R., Feb 2012, In: Journal of Clinical Endocrinology and Metabolism. p. E248-56 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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SCORE2 risk prediction algorithms: new models to estimate 10-year risk of cardiovascular disease in Europe
Hageman, S., Pennells, L., Ojeda, F., Kaptoge, S., Kuulasmaa, K., de Vries, T., Xu, Z., Kee, F., Chung, R., Wood, A., McEvoy, J. W., Veronesi, G., Bolton, T., Dendale, P., Ference, B. A., Halle, M., Timmis, A., Vardas, P., Danesh, J., Graham, I. & 32 others, , 2021, In: European Heart Journal. 42, 25, p. 2439-2454 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Apolipoprotein M and Risk of Type 2 Diabetes
Hajny, Stefan, Christoffersen, M., Dalila, N., Nielsen, L. B., Tybjærg-Hansen, Anne & Christoffersen, Christina, 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 9, p. 3046-3057Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Actionability and familial uptake following opportunistic genomic screening in a pediatric cancer cohort
Hammer-Hansen, S., Stoltze, U., Bartels, Emil Daniel, Hansen, Thomas van Overeem, Byrjalsen, A., Tybjærg-Hansen, Anne, Juul, K., Schmiegelow, Kjeld, Tfelt-Hansen, Jacob, Bundgård, Henning, Wadt, Karin Anna Wallentin & Diness, Birgitte Rode, 2024, (E-pub ahead of print) In: European Journal of Human Genetics. 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic Variants Associated With Increased Plasma Levels of Triglycerides, via Effects on the Lipoprotein Lipase Pathway, Increase Risk of Acute Pancreatitis
Hansen, S. E. J., Madsen, C. M., Varbo, A., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2021, In: Clinical Gastroenterology and Hepatology. 19, 8, p. 1652-1660.e6Research output: Contribution to journal › Journal article › Research › peer-review
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Low and high pancreatic amylase is associated with pancreatic cancer and chronic pancreatitis
Hansen, S. E. J., Langsted, A., Varbo, A., Madsen, C. M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2021, In: European Journal of Epidemiology. 36, p. 975–984Research output: Contribution to journal › Journal article › Research › peer-review
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Comparison of sixteen serological SARS-CoV-2 immunoassays in sixteen clinical laboratories
Harritshøj, L. H., Gybel-Brask, M., Afzal, S., Kamstrup, P. R., Jørgensen, C. S., Thomsen, M. K., Hilsted, L., Friis-Hansen, L., Szecsi, P. B., Pedersen, L., Nielsen, L., Hansen, C. B., Garred, P., Korsholm, T-L., Mikkelsen, S., Nielsen, K. O., Møller, B. K., Hansen, A. T., Iversen, K. K., Nielsen, P. B. & 18 others, , 11 Feb 2021, In: Journal of Clinical Microbiology. 59, 5, e02596-20.Research output: Contribution to journal › Journal article › Research › peer-review
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C-reactive protein levels and risk of dementia — Observational and genetic studies of 111,242 individuals from the general population
Hegazy, S. H., Thomassen, J. Q., Rasmussen, I. J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Alzheimer's & Dementia. 18, 11, p. 2262-2271 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The polygenic nature of hypertriglyceridaemia: implications for definition, diagnosis, and management
Hegele, R. A., Ginsberg, H. N., Chapman, M. J., Nordestgaard, B. G., Kuivenhoven, J. A., Averna, M., Borén, J., Bruckert, E., Catapano, A. L., Descamps, O. S., Hovingh, G. K., Humphries, S. E., Kovanen, P. T., Masana, L., Pajukanta, P., Parhofer, K. G., Raal, F. J., Ray, K. K., Santos, R. D., Stalenhoef, A. F. H. & 6 others, , Aug 2014, In: The Lancet Diabetes & Endocrinology. 2, 8, p. 655-666 12 p.Research output: Contribution to journal › Review › Research › peer-review
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Endogenous sex hormones and risk of venous thromboembolism in women and men
Holmegard, H. N., Nordestgaard, Børge, Schnohr, P., Tybjærg-Hansen, Anne & Benn, Marianne, 2014, In: Journal of Thrombosis and Haemostasis. 12, 3, p. 297-305 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Sex Hormones and Ischemic Stroke: A Prospective Cohort Study and Meta-Analyses
Holmegard, H. N., Nordestgaard, Børge, Jensen, G. B., Tybjærg-Hansen, Anne & Benn, Marianne, Jan 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 1, p. 69-78 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Response to the Letter: Response to "Use of biomarkers to identify new drug targets and to predict risk of cardiometabolic outcomes" by Abasi A., et al
Holmegard, H. N., Nordestgaard, Børge, Jensen, G. B., Tybjærg-Hansen, Anne & Benn, Marianne, Feb 2016, In: The Journal of clinical endocrinology and metabolism. 101, 2, p. L22-L23Research output: Contribution to journal › Letter › Research › peer-review
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A systematic review and meta-analysis of 130,000 individuals shows smoking does not modify the association of APOE genotype on risk of coronary heart disease
Holmes, M. V., Frikke-Schmidt, R., Melis, D., Luben, R., Asselbergs, F. W., Boer, J. M. A., Cooper, J., Palmen, J., Horvat, P., Engmann, J., Li, K-W., Onland-Moret, N. C., Hofker, M. H., Kumari, M., Keating, B. J., Hubacek, J. A., Adamkova, V., Kubinova, R., Bobak, M., Khaw, K-T. & 6 others, , Nov 2014, In: Atherosclerosis. 237, 1, p. 5-12 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Secretory Phospholipase A2-IIA and Cardiovascular Disease
Holmes, M. V., Simon, T., Exeter, H. J., Folkersen, L. W., Asselbergs, F. W., Guardiola, M., Cooper, J. A., Palmen, J., Hubacek, J. A., Carruthers, K. F., Horne, B. D., Brunisholz, K. D., Mega, J. L., van Iperen, E. P. A., Li, M., Leusink, M., Trompet, S., Verschuren, J. J. W., Hovingh, G. K., Dehghan, A. & 93 others, , 2013, In: Journal of the American College of Cardiology. 62 , 21, p. 1966–1976 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Heterozygosity for R1141X in Abcc6 and Risk of Ischemic Vascular Disease
Hornstrup, L. S., Tybjaerg-Hansen, A., Haase, C. L., Nordestgaard, Børge, Grande, P., Frikke-Schmidt, Ruth & Tybjærg-Hansen, Anne, 2010, In: Atherosclerosis. Supplement. 11, 2, p. 38 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Genetic stabilization of transthyretin, cerebrovascular disease, and life expectancy
Hornstrup, L. S., Frikke-Schmidt, R., Nordestgaard, Børge & Tybjærg-Hansen, Anne, Jun 2013, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 33, 6, p. 1441-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Heterozygosity for R1141X in ABCC6 and risk of ischemic vascular disease
Hornstrup, L. S., Tybjærg-Hansen, Anne, Haase, C. L., Nordestgaard, Børge, Sillesen, H., Grande, P. & Frikke-Schmidt, R., 2011, In: Circulation: Cardiovascular Genetics. 4, 5, p. 534-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fifteen new risk loci for coronary artery disease highlight arterial-wall-specific mechanisms
Howson, J. M. M., Zhao, W., Barnes, D. R., Ho, W. K., Young, R., Paul, D. S., Waite, L., Freitag, D. F., Fauman, E. B., Salfati, E. L., Sun, B. B., Eicher, J. D., Johnson, A. D., Sheu, W. H-H., Nielsen, S. F., Lin, W-Y., Surendran, P., Malarstig, A., Wilk, J. B., Tybjærg-Hansen, A. & 36 others, , 2017, In: Nature Genetics. 49, p. 1113-1119Research output: Contribution to journal › Letter › Research › peer-review
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Improved imputation of low-frequency and rare variants using the UK10K haplotype reference panel
Huang, J., Howie, B., Mccarthy, S., Memari, Y., Walter, K., Min, J. L., Danecek, P., Malerba, G., Trabetti, E., Zheng, H., Al Turki, S., Amuzu, A., Anderson, C. A., Anney, R., Antony, D., Artigas, M. S., Ayub, M., Bala, S., Barrett, J. C., Barroso, I. & 219 others, , 2015, In: Nature Communications. 6, 9 p., 8111.Research output: Contribution to journal › Journal article › Research › peer-review
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Systematically missing confounders in individual participant data meta-analysis of observational cohort studies
Jackson, D., White, I., Kostis, J. B., Wilson, A. C., Folsom, A. R., Wu, K., Chambless, L., Benderly, M., Goldbourt, U., Willeit, J., Kiechl, S., Yarnell, J. W., Sweetnam, P. M., Elwood, P. C., Cushman, M., Psaty, B. M., Tracy, R. P., Tybjaerg-Hansen, A., Haverkate, F., Maat, M. P. D. & 98 others, , 2009, In: Statistics in Medicine. 28, 8, p. 1218-1237 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hepatic lipase, genetically elevated high-density lipoprotein, and risk of ischemic cardiovascular disease
Johannsen, T. H., Kamstrup, P. R., Andersen, R. V., Jensen, G. B., Sillesen, Henrik, Tybjærg-Hansen, Anne & Nordestgaard, B. G., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1264-73 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Genetic inhibition of CETP, ischemic vascular disease and mortality, and possible adverse effects
Johannsen, T. H., Frikke-Schmidt, R., Schou, J., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2012, In: Journal of the American College of Cardiology. 60, 20, p. 2041-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma YKL-40 and total and disease-specific mortality in the general population
Johansen, Julia Sidenius, Bojesen, Stig Egil, Tybjærg-Hansen, Anne, Mylin, A. K., Price, P. A. & Nordestgaard, Børge, 1 Oct 2010, In: Clinical Chemistry. 56, 10, p. 1580-91 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Common Genetic Variation in Apoa5, Levels of Triglycerides and Risk of Myocardial Infarction in the General Population
Jorgensen, A. B., Frikke-Schmidt, Ruth, Grande, P., Nordestgaard, Børge, Tybjaerg-Hansen, A. & Tybjærg-Hansen, Anne, 2010, In: Atherosclerosis. Supplement. 11, 2, p. 89 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Four Susceptibility Loci for Gallstone Disease Identified in a Meta-analysis of Genome-Wide Association Studies
Joshi, A. D., Andersson, C., Buch, S., Stender, S., Noordam, R., Weng, L-C., Weeke, P. E., Auer, P. L., Boehm, B., Chen, C., Choi, H., Curhan, G., Denny, J. C., De Vivo, I., Eicher, J. D., Ellinghaus, D., Folsom, A. R., Fuchs, C., Gala, M., Haessler, J. & 35 others, , Aug 2016, In: Gastroenterology. 151, 2, 351 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Factor V leiden homozygosity, dyspnea, and reduced pulmonary function.
Juul, K., Tybjærg-Hansen, A., Lange, P., Vestbo, J., Nordestgaard, B., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2005, In: Archives of Internal Medicine.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetically increased antioxidative protection and decreased chronic obstructive pulmonary disease
Juul, K., Tybjærg-Hansen, A., Marklund, S., Lange, Peter, Nordestgaard, B. G. & Tybjærg-Hansen, Anne, 2006, In: American Journal of Respiratory and Critical Care Medicine. 173, 8, p. 858-64Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetisk betinget reduktion i antioxidativ beskyttelse og øget risiko for iskaemisk hjertesygdom--sekundaerpublikation
Juul, K., Tybjærg-Hansen, Anne, Marklund, S., Heegaard, N. H. H., Steffensen, R., Sillesen, H. H., Jensen, G. B. & Nordestgaard, Børge, 2005, In: Ugeskrift for Laeger. 167, 7, p. 767-70 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Blood–brain barrier transcytosis genes, risk of dementia and stroke: a prospective cohort study of 74,754 individuals
Juul Rasmussen, I., Tybjærg-Hansen, Anne, Rasmussen, K. L., Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2019, In: European Journal of Epidemiology. 34, 6, p. 579-590 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of cardiovascular risk factors and genetics on 10-year absolute risk of dementia: risk charts for targeted prevention
Juul Rasmussen, I., Rasmussen, K. L., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2020, In: European Heart Journal. 41, 41, p. 4024-4033 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physical activity in leisure time and at work and risk of dementia: A prospective cohort study of 117,616 individuals
Juul Rasmussen, I., Rasmussen, Katrine Laura, Thomassen, J. Q., Nordestgaard, Børge, Schnohr, P., Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Atherosclerosis. 360, p. 53-60 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetically elevated non-fasting triglycerides and calculated remnant cholesterol as causal risk factors for myocardial infarction
Jørgensen, A. B., Frikke-Schmidt, R., West, A. S., Grande, P., Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2012, In: European Heart Journal.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss-of-Function Mutations in APOC3 and Risk of Ischemic Vascular Disease
Jørgensen, A. B., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, Jul 2014, In: New England Journal of Medicine. 371, 1, p. 32-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pentanucleotide repeat polymorphism, lipoprotein(a) levels, and risk of ischemic heart disease
Kamstrup, P. R., Tybjærg-Hansen, Anne, Steffensen, R. & Nordestgaard, B. G., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 3769-3776 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated lipoprotein(a) and risk of aortic valve stenosis in the general population
Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 11 Feb 2014, In: Journal of the American College of Cardiology. 63, 5, p. 470-477 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetically elevated lipoprotein(a) and increased risk of myocardial infarction
Kamstrup, P. R., Tybjærg-Hansen, Anne, Steffensen, R., Nordestgaard, B. G., Kamstrup, P. R., Tybjærg-Hansen, Anne, Steffensen, R. & Nordestgaard, Børge, 2009, In: JAMA - Journal of the American Medical Association. 301, 22, p. 2331-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lipoprotein(a) and risk of myocardial infarction--genetic epidemiologic evidence of causality
Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2011, In: Scandinavian Journal of Clinical & Laboratory Investigation. 71, 2, p. 87-93 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extreme lipoprotein(a) levels and risk of myocardial infarction in the general population: the Copenhagen City Heart Study
Kamstrup, P. R., Benn, M., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2008, In: Circulation. 117, 2, p. 176-84 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extreme lipoprotein(a) levels and improved cardiovascular risk prediction
Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 19 Mar 2013, In: Journal of the American College of Cardiology. 61, 11, p. 1146-56 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic evidence that lipoprotein(a) associates with atherosclerotic stenosis rather than venous thrombosis
Kamstrup, P. R., Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2012, In: Arteriosclerosis, Thrombosis, and Vascular Biology. 32, 7, p. 1732-41 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
C-reactive protein, fibrinogen, and cardiovascular disease prediction
Kaptoge, S., Di Angelantonio, E., Pennells, L., Wood, A. M., White, I. R., Gao, P., Walker, M., Thompson, A., Sarwar, N., Caslake, M., Butterworth, A. S., Amouyel, P., Assmann, G., Bakker, S. J. L., Barr, E. L. M., Barrett-Connor, E., Benjamin, E. J., Björkelund, C., Brenner, H., Brunner, E. & 31 others, , 2012, In: New England Journal of Medicine. 367, 14, p. 1310-20 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma levels of 27-hydroxycholesterol in humans and mice with monogenic disturbances of high density lipoprotein metabolism
Karuna, R., Holleboom, A. G., Motazacker, M. M., Kuivenhoven, J. A., Frikke-Schmidt, Ruth, Tybjærg-Hansen, Anne, Georgopoulos, S., van Eck, M., van Berkel, T. J. C., von Eckardstein, A. & Rentsch, K. M., 1 Feb 2011, In: Atherosclerosis. 214, 2, p. 448-55 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CYP1B1 genotype and risk of cardiovascular disease, pulmonary disease, and cancer in 50,000 individuals
Knudsen, Diljit Kaur, Nordestgaard, B. G., Tybjærg-Hansen, Anne & Bojesen, S. E., 2009, In: Pharmacogenetics and Genomics (Print Edition). 19, 9, p. 685-694 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nicotinic acetylcholine receptor polymorphism, smoking behavior, and tobacco-related cancer and lung and cardiovascular diseases: a cohort study
Kaur-Knudsen, D., Bojesen, Stig Egil, Tybjærg-Hansen, Anne & Nordestgaard, Børge, 2011, In: Journal of Clinical Oncology. 29, 21, p. 2875-82 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Apolipoprotein E genotype, cardiovascular biomarkers and risk of stroke: Systematic review and meta-analysis of 14 015 stroke cases and pooled analysis of primary biomarker data from up to 60 883 individuals
Khan, T. A., Shah, T., Prieto, D., Zhang, W., Price, J., Fowkes, G. R., Cooper, J., Talmud, P. J., Humphries, S. E., Sundstrom, J., Hubacek, J. A., Ebrahim, S., Lawlor, D. A., Ben-Shlomo, Y., Abdollahi, M. R., Slooter, A. J. C., Szolnoki, Z., Sandhu, M., Wareham, N., Frikke-Schmidt, R. & 29 others, , 2013, In: International Journal of Epidemiology. 42, 2, p. 475-492 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Estrogen receptor alpha polymorphism and risk of cardiovascular disease, cancer, and hip fracture: cross-sectional, cohort, and case-control studies and a meta-analysis
Kjaergaard, A., Ellervik, C., Tybjaerg-Hansen, A., Axelsson, C., Grønholdt, M., Grande, P., Jensen, G. B., Nordestgaard, B., Tybjærg-Hansen, Anne, Kjaergaard, A. D., Ellervik, Christina, Axelsson, C. K., Grønholdt, M., Grande, P. & Nordestgaard, Børge, 2007, In: Circulation. 115, 7, p. 861-71 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adherence to dietary guidelines and risk of dementia: a prospective cohort study of 94 184 individuals
Kjeldsen, E. W., Thomassen, J. Q., Rasmussen, Katrine Laura, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Epidemiology and Psychiatric Sciences. 31, e71.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of diet on ten-year absolute cardiovascular risk in a prospective cohort of 94 321 individuals: A tool for implementation of healthy diets
Kjeldsen, E. W., Thomassen, J. Q., Rasmussen, Katrine Laura, Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: The Lancet Regional Health - Europe. 19, 100419.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ABCA7 and risk of dementia and vascular disease in the Danish population
Kjeldsen, E. W., Tybjærg-Hansen, Anne, Nordestgaard, Børge & Frikke-Schmidt, Ruth, 2018, In: Annals of Clinical and Translational Neurology. 5, 1, p. 41-51 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma high-density lipoprotein cholesterol and risk of dementia: observational and genetic studies
Kjeldsen, E. W., Thomassen, J. Q., Juul Rasmussen, I., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Frikke-Schmidt, Ruth, 2022, In: Cardiovascular Research. 118, 5, p. 1330-1343 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated Fibrinogen Levels Associate with Risk of Pulmonary Embolism, but not with Deep Venous Thrombosis
Klovaite, J., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Benn, M., 2013, In: American Journal of Respiratory and Critical Care Medicine. 187, 3, p. 286-93Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Using genetics to explore whether the cholesterol-lowering drug ezetimibe may cause an increased risk of cancer
Kobberø Lauridsen, B., Stender, S., Frikke-Schmidt, Ruth, Nordestgaard, Børge & Tybjærg-Hansen, Anne, 2017, In: International Journal of Epidemiology. 46, 6, p. 1777-1785Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Postprandial Hypertriglyceridaemia Revisited in the Era of Non-fasting Lipid Profiles: Executive Summary of a 2019 Expert Panel Statement
Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, Anne, Tentolouris, N. & Nordestgaard, Børge, 2019, In: Current Vascular Pharmacology. 17, 5, p. 538-540Research output: Contribution to journal › Review › Research › peer-review
- Published
Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Narrative Review
Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, Anne, Tentolouris, N. & Nordestgaard, Børge, 2019, In: Current Vascular Pharmacology. 17, 5, p. 515-537Research output: Contribution to journal › Review › Research › peer-review
- Published
Postprandial Hypertriglyceridaemia Revisited in the Era of Non-Fasting Lipid Profile Testing: A 2019 Expert Panel Statement, Main Text
Kolovou, G. D., Watts, G. F., Mikhailidis, D. P., Pérez-Martínez, P., Mora, S., Bilianou, H., Panotopoulos, G., Katsiki, N., Ooi, T. C., Lopez-Miranda, J., Tybjærg-Hansen, Anne, Tentolouris, N. & Nordestgaard, Børge, 2019, In: Current Vascular Pharmacology. 17, 5, p. 498-514Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Seven prostate cancer susceptibility loci identified by a multi-stage genome-wide association study
Kote-Jarai, Z., Olama, A. A. A., Giles, G. G., Severi, G., Schleutker, J., Weischer, M., Campa, D., Riboli, E., Key, T., Gronberg, H., Hunter, D. J., Kraft, P., Thun, M. J., Ingles, S., Chanock, S., Albanes, D., Hayes, R. B., Neal, D. E., Hamdy, F. C., Donovan, J. L. & 31 others, , 2011, In: Nature Genetics. 43, 8, p. 785-91 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exome-wide association study identifies a TM6SF2 variant that confers susceptibility to nonalcoholic fatty liver disease
Kozlitina, J., Smagris, E., Stender, Stefan, Nordestgaard, Børge, Zhou, H. H., Tybjærg-Hansen, Anne, Vogt, T. F., Hobbs, H. H. & Cohen, J. C., Apr 2014, In: Nature Genetics. 46, 4, p. 352-356 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of APOE ε Genotype on Lipoprotein(a) and the Associated Risk of Myocardial Infarction and Aortic Valve Stenosis
Kritharides, L., Nordestgaard, Børge, Tybjærg-Hansen, Anne, Kamstrup, P. R. & Afzal, Shoaib, 1 Sep 2017, In: Journal of Clinical Endocrinology and Metabolism. 102, 9, p. 3390-3399 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High fat in blood and body and increased risk of clinically diagnosed non-alcoholic fatty liver disease in 105,981 individuals
Kyhl, L. K., Nordestgaard, Børge, Tybjærg-Hansen, Anne & Nielsen, S. F., 2023, In: Atherosclerosis. 376, p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 924951
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ABCA7 and risk of dementia and vascular disease in the Danish population
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The UK10K project identifies rare variants in health and disease
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Data on plasma levels of apolipoprotein E, correlations with lipids and lipoproteins stratified by APOE genotype, and risk of ischemic heart disease
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