Trichotillomania and its clinical relationship to depression and anxiety
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Trichotillomania and its clinical relationship to depression and anxiety. / Grant, Jon E.; Redden, Sarah A.; Medeiros, Gustavo C.; Odlaug, Brian L.; Curley, Erin E.; Tavares, Hermano; Keuthen, Nancy J.
In: International Journal of Psychiatry in Clinical Practice, Vol. 21, No. 4, 2017, p. 302-306.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Trichotillomania and its clinical relationship to depression and anxiety
AU - Grant, Jon E.
AU - Redden, Sarah A.
AU - Medeiros, Gustavo C.
AU - Odlaug, Brian L.
AU - Curley, Erin E.
AU - Tavares, Hermano
AU - Keuthen, Nancy J.
PY - 2017
Y1 - 2017
N2 - Objective: Trichotillomania (TTM) is associated with high rates of co-occurring depression and anxiety disorders. What the co-occurrence of TTM, depression or anxiety disorders means clinically and cognitively, however, has garnered little research attention. Methods: About 530 adults with TTM were examined on a variety of clinical measures including symptom severity, psychosocial measures of functioning, psychiatric comorbidity and neurocognitive testing assessing motor inhibition and cognitive flexibility. Clinical features and cognitive functioning were compared between TTM patients with current comorbid major depressive disorder (MDD), a current anxiety disorder, both MDD and an anxiety disorder, or neither. Results: Of 530 participants, 58 (10.3%) had MDD only, 97 (18.3%) had an anxiety disorder only, 58 (10.3%) had both MDD and an anxiety disorder, and 317 (59.8%) had neither. For almost all clinical measures, those with MDD only reported worse symptoms than those with an anxiety disorder only, and the combination of MDD and an anxiety disorder reported the worst level of symptom severity. Conclusions: These results suggest that adults with TTM and co-occurring MDD and anxiety disorders exhibit unique clinical differences. The clinical differences may also have treatment implications.
AB - Objective: Trichotillomania (TTM) is associated with high rates of co-occurring depression and anxiety disorders. What the co-occurrence of TTM, depression or anxiety disorders means clinically and cognitively, however, has garnered little research attention. Methods: About 530 adults with TTM were examined on a variety of clinical measures including symptom severity, psychosocial measures of functioning, psychiatric comorbidity and neurocognitive testing assessing motor inhibition and cognitive flexibility. Clinical features and cognitive functioning were compared between TTM patients with current comorbid major depressive disorder (MDD), a current anxiety disorder, both MDD and an anxiety disorder, or neither. Results: Of 530 participants, 58 (10.3%) had MDD only, 97 (18.3%) had an anxiety disorder only, 58 (10.3%) had both MDD and an anxiety disorder, and 317 (59.8%) had neither. For almost all clinical measures, those with MDD only reported worse symptoms than those with an anxiety disorder only, and the combination of MDD and an anxiety disorder reported the worst level of symptom severity. Conclusions: These results suggest that adults with TTM and co-occurring MDD and anxiety disorders exhibit unique clinical differences. The clinical differences may also have treatment implications.
KW - anxiety
KW - cognition
KW - comorbidity
KW - depression
KW - Trichotillomania
U2 - 10.1080/13651501.2017.1314509
DO - 10.1080/13651501.2017.1314509
M3 - Journal article
C2 - 28429625
AN - SCOPUS:85018839361
VL - 21
SP - 302
EP - 306
JO - International Journal of Psychiatry in Clinical Practice
JF - International Journal of Psychiatry in Clinical Practice
SN - 1365-1501
IS - 4
ER -
ID: 196716400