Topoisomerase 1(TOP1) gene copy number in stage III colorectal cancer patients and its relation to prognosis

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A Topoisomerase 1 (Top1) poison is frequently included in the treatment regimens for metastatic colorectal cancer (mCRC). However, no predictive biomarkers for Top1 poisons are available. We here report a study on the TOP1 gene copy number in CRC patients and its association with patient prognosis and tumor cell proliferation.
Original languageEnglish
JournalMolecular Oncology
Issue number1
Pages (from-to)101-111
Number of pages11
Publication statusPublished - 2013

ID: 40707423