Pharmacological characterization of social isolation-induced hyperactivity

Research output: Contribution to journalJournal articleResearchpeer-review

Social isolation (SI) of rats directly after weaning is a non-pharmacological, non-lesion animal model based on the neurodevelopmental hypothesis of schizophrenia. The model causes several neurobiological and behavioral alterations consistent with observations in schizophrenia.
Original languageEnglish
Issue number2
Pages (from-to)257-66
Number of pages10
Publication statusPublished - 2011

    Research areas

  • Acoustic Stimulation, Analysis of Variance, Animals, Animals, Newborn, Antipsychotic Agents, Behavior, Animal, Cohort Studies, Dose-Response Relationship, Drug, Hyperkinesis, Inhibition (Psychology), Male, Motor Activity, Psychoacoustics, Random Allocation, Rats, Social Isolation, Time Factors

ID: 37581644