PET/MR in oncology: an introduction with focus on MR and future perspectives for hybrid imaging
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PET/MR in oncology : an introduction with focus on MR and future perspectives for hybrid imaging. / Balyasnikova, Svetlana; Löfgren, Johan; de Nijs, Robin; Zamogilnaya, Yanna; Højgaard, Liselotte; Fischer, Barbara M.
In: American Journal of Nuclear Medicine and Molecular Imaging, Vol. 2, No. 4, 2012, p. 458-74.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - PET/MR in oncology
T2 - an introduction with focus on MR and future perspectives for hybrid imaging
AU - Balyasnikova, Svetlana
AU - Löfgren, Johan
AU - de Nijs, Robin
AU - Zamogilnaya, Yanna
AU - Højgaard, Liselotte
AU - Fischer, Barbara M
PY - 2012
Y1 - 2012
N2 - After more than 20 years of research, a fully integrated PET/MR scanner was launched in 2010 enabling simultaneous acquisition of PET and MR imaging. Currently, no clinical indication for combined PET/MR has been established, however the expectations are high. In this paper we will discuss some of the challenges inherent in this new technology, but focus on potential applications for simultaneous PET/MR in the field of oncology. Methods and tracers for use with the PET technology will be familiar to most readers of this journal; thus this paper aims to provide a short and basic introduction to a number of different MRI techniques, such as DWI-MR (diffusion weighted imaging MR), DCE-MR (dynamic contrast enhanced MR), MRS (MR spectroscopy) and MR for attenuation correction of PET. All MR techniques presented in this paper have shown promising results in the treatment of patients with solid tumors and could be applied together with PET increasing the amount of information about the tissues of interest. The potential clinical benefit of applying PET/MR in staging, radiotherapy planning and treatment evaluation in oncology, as well as the research perspectives for the use of PET/MR in the development of new tracers and drugs will be discussed.
AB - After more than 20 years of research, a fully integrated PET/MR scanner was launched in 2010 enabling simultaneous acquisition of PET and MR imaging. Currently, no clinical indication for combined PET/MR has been established, however the expectations are high. In this paper we will discuss some of the challenges inherent in this new technology, but focus on potential applications for simultaneous PET/MR in the field of oncology. Methods and tracers for use with the PET technology will be familiar to most readers of this journal; thus this paper aims to provide a short and basic introduction to a number of different MRI techniques, such as DWI-MR (diffusion weighted imaging MR), DCE-MR (dynamic contrast enhanced MR), MRS (MR spectroscopy) and MR for attenuation correction of PET. All MR techniques presented in this paper have shown promising results in the treatment of patients with solid tumors and could be applied together with PET increasing the amount of information about the tissues of interest. The potential clinical benefit of applying PET/MR in staging, radiotherapy planning and treatment evaluation in oncology, as well as the research perspectives for the use of PET/MR in the development of new tracers and drugs will be discussed.
M3 - Journal article
VL - 2
SP - 458
EP - 474
JO - American Journal of Nuclear Medicine and Molecular Imaging
JF - American Journal of Nuclear Medicine and Molecular Imaging
SN - 2160-8407
IS - 4
ER -
ID: 48468225