Perioperative blood transfusion does not decrease survival after surgical treatment of spinal metastases

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Perioperative blood transfusion does not decrease survival after surgical treatment of spinal metastases. / Clausen, Caroline; Lönn, Lars; Morgen, Søren Schmidt; Nielsen, Michael Bachmann; Frevert, Susanne Christiansen; Johansson, Pär Ingemar; Dahl, Benny.

In: European Spine Journal, Vol. 23, No. 8, 08.2014, p. 1791-1796.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Clausen, C, Lönn, L, Morgen, SS, Nielsen, MB, Frevert, SC, Johansson, PI & Dahl, B 2014, 'Perioperative blood transfusion does not decrease survival after surgical treatment of spinal metastases', European Spine Journal, vol. 23, no. 8, pp. 1791-1796. https://doi.org/10.1007/s00586-014-3330-y

APA

Clausen, C., Lönn, L., Morgen, S. S., Nielsen, M. B., Frevert, S. C., Johansson, P. I., & Dahl, B. (2014). Perioperative blood transfusion does not decrease survival after surgical treatment of spinal metastases. European Spine Journal, 23(8), 1791-1796. https://doi.org/10.1007/s00586-014-3330-y

Vancouver

Clausen C, Lönn L, Morgen SS, Nielsen MB, Frevert SC, Johansson PI et al. Perioperative blood transfusion does not decrease survival after surgical treatment of spinal metastases. European Spine Journal. 2014 Aug;23(8):1791-1796. https://doi.org/10.1007/s00586-014-3330-y

Author

Clausen, Caroline ; Lönn, Lars ; Morgen, Søren Schmidt ; Nielsen, Michael Bachmann ; Frevert, Susanne Christiansen ; Johansson, Pär Ingemar ; Dahl, Benny. / Perioperative blood transfusion does not decrease survival after surgical treatment of spinal metastases. In: European Spine Journal. 2014 ; Vol. 23, No. 8. pp. 1791-1796.

Bibtex

@article{9dff1a3e3a71472b87ffa0767a0d08ba,

title = "Perioperative blood transfusion does not decrease survival after surgical treatment of spinal metastases",

abstract = "PURPOSE: To assess whether perioperative allogenic blood transfusions in patients undergoing surgical treatment for spinal metastases independently influence patient survival.METHODS: A retrospective study including 170 consecutive patients undergoing surgical treatment for spinal metastases in 2009 and 2010 at a tertiary referral center. Variables related to postoperative survival were all included in the same multivariable logistic regression analysis with either 3- or 12-month survival as the dependent variable. The independent variables were: transfusion of allogenic red blood cells, age at surgery, gender, preoperative hemoglobin, revised Tokuhashi score and no. of instrumented levels.RESULTS: Perioperative allogenic blood transfusion of 1-2 units was associated with increased 12-month survival [p = 0.049, odds ratio 2.619 (confidence interval 1.004-6.831)], but not with 3-month survival. Larger transfusion volumes did not significantly influence survival.CONCLUSION: The results of the present study support that perioperative blood transfusion of <5 units does not decrease survival in patients operated for spinal metastases. Transfusion of 1-2 units seems to be associated with increased 12-month survival. Future studies should assess if a liberal transfusion regime can be applied to this group of patients; thereby, prioritizing early postoperative mobilization.",

keywords = "Aged, Blood Transfusion, Female, Follow-Up Studies, Humans, Male, Middle Aged, Odds Ratio, Preoperative Care, Retrospective Studies, Spinal Neoplasms, Survival Rate, Treatment Outcome",

author = "Caroline Clausen and Lars L{\"o}nn and Morgen, {S{\o}ren Schmidt} and Nielsen, {Michael Bachmann} and Frevert, {Susanne Christiansen} and Johansson, {P{\"a}r Ingemar} and Benny Dahl",

year = "2014",

month = aug,

doi = "10.1007/s00586-014-3330-y",

language = "English",

volume = "23",

pages = "1791--1796",

journal = "European Spine Journal",

issn = "0940-6719",

publisher = "Springer",

number = "8",

}

RIS

TY - JOUR

T1 - Perioperative blood transfusion does not decrease survival after surgical treatment of spinal metastases

AU - Clausen, Caroline

AU - Lönn, Lars

AU - Morgen, Søren Schmidt

AU - Nielsen, Michael Bachmann

AU - Frevert, Susanne Christiansen

AU - Johansson, Pär Ingemar

AU - Dahl, Benny

PY - 2014/8

Y1 - 2014/8

N2 - PURPOSE: To assess whether perioperative allogenic blood transfusions in patients undergoing surgical treatment for spinal metastases independently influence patient survival.METHODS: A retrospective study including 170 consecutive patients undergoing surgical treatment for spinal metastases in 2009 and 2010 at a tertiary referral center. Variables related to postoperative survival were all included in the same multivariable logistic regression analysis with either 3- or 12-month survival as the dependent variable. The independent variables were: transfusion of allogenic red blood cells, age at surgery, gender, preoperative hemoglobin, revised Tokuhashi score and no. of instrumented levels.RESULTS: Perioperative allogenic blood transfusion of 1-2 units was associated with increased 12-month survival [p = 0.049, odds ratio 2.619 (confidence interval 1.004-6.831)], but not with 3-month survival. Larger transfusion volumes did not significantly influence survival.CONCLUSION: The results of the present study support that perioperative blood transfusion of <5 units does not decrease survival in patients operated for spinal metastases. Transfusion of 1-2 units seems to be associated with increased 12-month survival. Future studies should assess if a liberal transfusion regime can be applied to this group of patients; thereby, prioritizing early postoperative mobilization.

AB - PURPOSE: To assess whether perioperative allogenic blood transfusions in patients undergoing surgical treatment for spinal metastases independently influence patient survival.METHODS: A retrospective study including 170 consecutive patients undergoing surgical treatment for spinal metastases in 2009 and 2010 at a tertiary referral center. Variables related to postoperative survival were all included in the same multivariable logistic regression analysis with either 3- or 12-month survival as the dependent variable. The independent variables were: transfusion of allogenic red blood cells, age at surgery, gender, preoperative hemoglobin, revised Tokuhashi score and no. of instrumented levels.RESULTS: Perioperative allogenic blood transfusion of 1-2 units was associated with increased 12-month survival [p = 0.049, odds ratio 2.619 (confidence interval 1.004-6.831)], but not with 3-month survival. Larger transfusion volumes did not significantly influence survival.CONCLUSION: The results of the present study support that perioperative blood transfusion of <5 units does not decrease survival in patients operated for spinal metastases. Transfusion of 1-2 units seems to be associated with increased 12-month survival. Future studies should assess if a liberal transfusion regime can be applied to this group of patients; thereby, prioritizing early postoperative mobilization.

KW - Aged

KW - Blood Transfusion

KW - Female

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Middle Aged

KW - Odds Ratio

KW - Preoperative Care

KW - Retrospective Studies

KW - Spinal Neoplasms

KW - Survival Rate

KW - Treatment Outcome

U2 - 10.1007/s00586-014-3330-y

DO - 10.1007/s00586-014-3330-y

M3 - Journal article

C2 - 24866254

VL - 23

SP - 1791

EP - 1796

JO - European Spine Journal

JF - European Spine Journal

SN - 0940-6719

IS - 8

ER -

ID: 138376793