Molecular biomarkers have the potential to improve the diagnostic work-up of pancreatic cystic lesions

Research output: Contribution to journal › Review › Research › peer-review

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Molecular biomarkers have the potential to improve the diagnostic work-up of pancreatic cystic lesions. / Plougmann, Julie Isabelle; Klausen, Pia; Karstensen, John Gásdal; Vilmann, Peter; Hasselby, Jane Preuss; Hansen, Carsten Palnæs; Kalaitzakis, Evangelos.

In: Scandinavian Journal of Gastroenterology, Vol. 52, No. 9, 09.2017, p. 932-940.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Plougmann, JI, Klausen, P, Karstensen, JG, Vilmann, P, Hasselby, JP, Hansen, CP & Kalaitzakis, E 2017, 'Molecular biomarkers have the potential to improve the diagnostic work-up of pancreatic cystic lesions', Scandinavian Journal of Gastroenterology, vol. 52, no. 9, pp. 932-940. https://doi.org/10.1080/00365521.2017.1333628

APA

Plougmann, J. I., Klausen, P., Karstensen, J. G., Vilmann, P., Hasselby, J. P., Hansen, C. P., & Kalaitzakis, E. (2017). Molecular biomarkers have the potential to improve the diagnostic work-up of pancreatic cystic lesions. Scandinavian Journal of Gastroenterology, 52(9), 932-940. https://doi.org/10.1080/00365521.2017.1333628

Vancouver

Plougmann JI, Klausen P, Karstensen JG, Vilmann P, Hasselby JP, Hansen CP et al. Molecular biomarkers have the potential to improve the diagnostic work-up of pancreatic cystic lesions. Scandinavian Journal of Gastroenterology. 2017 Sep;52(9):932-940. https://doi.org/10.1080/00365521.2017.1333628

Author

Plougmann, Julie Isabelle ; Klausen, Pia ; Karstensen, John Gásdal ; Vilmann, Peter ; Hasselby, Jane Preuss ; Hansen, Carsten Palnæs ; Kalaitzakis, Evangelos. / Molecular biomarkers have the potential to improve the diagnostic work-up of pancreatic cystic lesions. In: Scandinavian Journal of Gastroenterology. 2017 ; Vol. 52, No. 9. pp. 932-940.

Bibtex

@article{8035f0c4f9a74325aeda8328112a91d8,
title = "Molecular biomarkers have the potential to improve the diagnostic work-up of pancreatic cystic lesions",
abstract = "Pancreatic cysts are increasingly diagnosed due to the widespread use of cross-sectional imaging, and some of these lesions harbor malignant potential. Mucinous cystic neoplasms and intraductal papillary mucinous neoplasms are the major premalignant cystic neoplasms of the pancreas. A variety of diagnostic tools are used to predict the malignant potential of these cysts, but specificity and sensitivity are limited. Thus, many patients undergo unnecessary operations for benign cysts. Balancing the risks of watchful waiting with those of operative management is key in managing these lesions. During the last decade, genetic changes of pancreatic cysts have been examined extensively to estimate their malignant potential. In this review, we provide an overview of the latest molecular and genetic aspects of pancreatic cysts and how they may contribute to the differential diagnosis in patients with pancreatic cystic neoplasms.",
keywords = "Journal Article",
author = "Plougmann, {Julie Isabelle} and Pia Klausen and Karstensen, {John G{\'a}sdal} and Peter Vilmann and Hasselby, {Jane Preuss} and Hansen, {Carsten Paln{\ae}s} and Evangelos Kalaitzakis",
year = "2017",
month = sep,
doi = "10.1080/00365521.2017.1333628",
language = "English",
volume = "52",
pages = "932--940",
journal = "Scandinavian Journal of Gastroenterology. Supplement",
issn = "0085-5928",
publisher = "Taylor & Francis",
number = "9",

}

RIS

TY - JOUR

T1 - Molecular biomarkers have the potential to improve the diagnostic work-up of pancreatic cystic lesions

AU - Plougmann, Julie Isabelle

AU - Klausen, Pia

AU - Karstensen, John Gásdal

AU - Vilmann, Peter

AU - Hasselby, Jane Preuss

AU - Hansen, Carsten Palnæs

AU - Kalaitzakis, Evangelos

PY - 2017/9

Y1 - 2017/9

N2 - Pancreatic cysts are increasingly diagnosed due to the widespread use of cross-sectional imaging, and some of these lesions harbor malignant potential. Mucinous cystic neoplasms and intraductal papillary mucinous neoplasms are the major premalignant cystic neoplasms of the pancreas. A variety of diagnostic tools are used to predict the malignant potential of these cysts, but specificity and sensitivity are limited. Thus, many patients undergo unnecessary operations for benign cysts. Balancing the risks of watchful waiting with those of operative management is key in managing these lesions. During the last decade, genetic changes of pancreatic cysts have been examined extensively to estimate their malignant potential. In this review, we provide an overview of the latest molecular and genetic aspects of pancreatic cysts and how they may contribute to the differential diagnosis in patients with pancreatic cystic neoplasms.

AB - Pancreatic cysts are increasingly diagnosed due to the widespread use of cross-sectional imaging, and some of these lesions harbor malignant potential. Mucinous cystic neoplasms and intraductal papillary mucinous neoplasms are the major premalignant cystic neoplasms of the pancreas. A variety of diagnostic tools are used to predict the malignant potential of these cysts, but specificity and sensitivity are limited. Thus, many patients undergo unnecessary operations for benign cysts. Balancing the risks of watchful waiting with those of operative management is key in managing these lesions. During the last decade, genetic changes of pancreatic cysts have been examined extensively to estimate their malignant potential. In this review, we provide an overview of the latest molecular and genetic aspects of pancreatic cysts and how they may contribute to the differential diagnosis in patients with pancreatic cystic neoplasms.

KW - Journal Article

U2 - 10.1080/00365521.2017.1333628

DO - 10.1080/00365521.2017.1333628

M3 - Review

C2 - 28552018

VL - 52

SP - 932

EP - 940

JO - Scandinavian Journal of Gastroenterology. Supplement

JF - Scandinavian Journal of Gastroenterology. Supplement

SN - 0085-5928

IS - 9

ER -

ID: 186645649