Genetiske undersøgelser i arbejdsmiljøsammenhaeng
Research output: Contribution to journal › Journal article › Research › peer-review
Standard
Genetiske undersøgelser i arbejdsmiljøsammenhaeng. / Knudsen, Lisbeth E.; Nørby, Søren.
In: Ugeskrift for læger, Vol. 156, No. 26, 1994, p. 3880-6.Research output: Contribution to journal › Journal article › Research › peer-review
Harvard
APA
Vancouver
Author
Bibtex
}
RIS
TY - JOUR
T1 - Genetiske undersøgelser i arbejdsmiljøsammenhaeng
AU - Knudsen, Lisbeth E.
AU - Nørby, Søren
N1 - Keywords: Evaluation Studies as Topic; Genetic Techniques; Genetic Testing; Humans; Occupational Exposure; Risk Factors
PY - 1994
Y1 - 1994
N2 - Individuals with an increased risk of occupationally and nonoccupationally induced adverse health effects may be identified by genetic monitoring and genetic screening. Genetic monitoring of induced genetic changes is performed by measurements of chromosomal aberrations or DNA-lesions. Genetic screening includes detection of inherited traits by measurements of enzyme activities in blood, the presence of a specific gene or a specific mutation. Inherited serum alpha-1-antitrypsin deficiency increases the risk of developing a chronic obstructive pulmonary disease. The risk is exacerbated by occupational exposure to dust. The available methods used for genetic screening of individual susceptibility to occupational exposures are not sufficiently validated for routine use. This is especially relevant concerning the population validity referring to how well the markers depict an event in a population. Legal and ethical aspects of preemployment genetic testing are currently discussed in Denmark. Udgivelsesdato: 1994-Jun-27
AB - Individuals with an increased risk of occupationally and nonoccupationally induced adverse health effects may be identified by genetic monitoring and genetic screening. Genetic monitoring of induced genetic changes is performed by measurements of chromosomal aberrations or DNA-lesions. Genetic screening includes detection of inherited traits by measurements of enzyme activities in blood, the presence of a specific gene or a specific mutation. Inherited serum alpha-1-antitrypsin deficiency increases the risk of developing a chronic obstructive pulmonary disease. The risk is exacerbated by occupational exposure to dust. The available methods used for genetic screening of individual susceptibility to occupational exposures are not sufficiently validated for routine use. This is especially relevant concerning the population validity referring to how well the markers depict an event in a population. Legal and ethical aspects of preemployment genetic testing are currently discussed in Denmark. Udgivelsesdato: 1994-Jun-27
M3 - Tidsskriftartikel
C2 - 8059470
VL - 156
SP - 3880
EP - 3886
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 26
ER -
ID: 19231647