The Role of a Colon-in-Continuity in Short Bowel Syndrome

Research output: Contribution to journal › Review › Research › peer-review

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The Role of a Colon-in-Continuity in Short Bowel Syndrome. / Verbiest, Astrid; Jeppesen, Palle Bekker; Joly, Francisca; Vanuytsel, Tim.

In: Nutrients, Vol. 15, No. 3, 628, 2023.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Verbiest, A, Jeppesen, PB, Joly, F & Vanuytsel, T 2023, 'The Role of a Colon-in-Continuity in Short Bowel Syndrome', Nutrients, vol. 15, no. 3, 628. https://doi.org/10.3390/nu15030628

APA

Verbiest, A., Jeppesen, P. B., Joly, F., & Vanuytsel, T. (2023). The Role of a Colon-in-Continuity in Short Bowel Syndrome. Nutrients, 15(3), [628]. https://doi.org/10.3390/nu15030628

Vancouver

Verbiest A, Jeppesen PB, Joly F, Vanuytsel T. The Role of a Colon-in-Continuity in Short Bowel Syndrome. Nutrients. 2023;15(3). 628. https://doi.org/10.3390/nu15030628

Author

Verbiest, Astrid ; Jeppesen, Palle Bekker ; Joly, Francisca ; Vanuytsel, Tim. / The Role of a Colon-in-Continuity in Short Bowel Syndrome. In: Nutrients. 2023 ; Vol. 15, No. 3.

Bibtex

@article{029a7061b31a4c9c9118e9c0e6d50a2a,

title = "The Role of a Colon-in-Continuity in Short Bowel Syndrome",

abstract = "Short bowel syndrome (SBS) is a rare gastrointestinal condition that is defined as having less than 200 cm of remaining small intestine. SBS results from extensive surgical resection and is associated with a high risk for intestinal failure (IF) with a need for parenteral support (PS). Depending on the region of intestinal resection, three different main anatomy types can be distinguished from each other. In this review, we synthesize the current knowledge on the role of the colon in the setting of SBS-IF with a colon-in-continuity (SBS-IF-CiC), e.g., by enhancing the degree of intestinal adaptation, energy salvage, and the role of the microbiota. In addition, the effect of the disease-modifying treatment with glucagon-like peptide-2 (GLP-2) analogs in SBS-IF-CiC and how it differs from patients without a colon will be discussed. Overall, the findings explained in this review highlight the importance of preservation of the colon in SBS-IF.",

keywords = "colon-in-continuity, glucagon-like peptide-2 analogs, intestinal adaptation, intestinal failure, parenteral support, short bowel syndrome",

author = "Astrid Verbiest and Jeppesen, {Palle Bekker} and Francisca Joly and Tim Vanuytsel",

note = "Publisher Copyright: {\textcopyright} 2023 by the authors.",

year = "2023",

doi = "10.3390/nu15030628",

language = "English",

volume = "15",

journal = "Nutrients",

issn = "2072-6643",

publisher = "M D P I AG",

number = "3",

}

RIS

TY - JOUR

T1 - The Role of a Colon-in-Continuity in Short Bowel Syndrome

AU - Verbiest, Astrid

AU - Jeppesen, Palle Bekker

AU - Joly, Francisca

AU - Vanuytsel, Tim

PY - 2023

Y1 - 2023

N2 - Short bowel syndrome (SBS) is a rare gastrointestinal condition that is defined as having less than 200 cm of remaining small intestine. SBS results from extensive surgical resection and is associated with a high risk for intestinal failure (IF) with a need for parenteral support (PS). Depending on the region of intestinal resection, three different main anatomy types can be distinguished from each other. In this review, we synthesize the current knowledge on the role of the colon in the setting of SBS-IF with a colon-in-continuity (SBS-IF-CiC), e.g., by enhancing the degree of intestinal adaptation, energy salvage, and the role of the microbiota. In addition, the effect of the disease-modifying treatment with glucagon-like peptide-2 (GLP-2) analogs in SBS-IF-CiC and how it differs from patients without a colon will be discussed. Overall, the findings explained in this review highlight the importance of preservation of the colon in SBS-IF.

AB - Short bowel syndrome (SBS) is a rare gastrointestinal condition that is defined as having less than 200 cm of remaining small intestine. SBS results from extensive surgical resection and is associated with a high risk for intestinal failure (IF) with a need for parenteral support (PS). Depending on the region of intestinal resection, three different main anatomy types can be distinguished from each other. In this review, we synthesize the current knowledge on the role of the colon in the setting of SBS-IF with a colon-in-continuity (SBS-IF-CiC), e.g., by enhancing the degree of intestinal adaptation, energy salvage, and the role of the microbiota. In addition, the effect of the disease-modifying treatment with glucagon-like peptide-2 (GLP-2) analogs in SBS-IF-CiC and how it differs from patients without a colon will be discussed. Overall, the findings explained in this review highlight the importance of preservation of the colon in SBS-IF.

KW - colon-in-continuity

KW - glucagon-like peptide-2 analogs

KW - intestinal adaptation

KW - intestinal failure

KW - parenteral support

KW - short bowel syndrome

U2 - 10.3390/nu15030628

DO - 10.3390/nu15030628

M3 - Review

C2 - 36771335

AN - SCOPUS:85147802754

VL - 15

JO - Nutrients

JF - Nutrients

SN - 2072-6643

IS - 3

M1 - 628

ER -

ID: 367837289