The HUNT study: A population-based cohort for genetic research
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The HUNT study : A population-based cohort for genetic research. / Brumpton, Ben M.; Graham, Sarah; Surakka, Ida; Skogholt, Anne Heidi; Løset, Mari; Fritsche, Lars G.; Wolford, Brooke; Zhou, Wei; Nielsen, Jonas Bille; Holmen, Oddgeir L.; Gabrielsen, Maiken E.; Thomas, Laurent; Bhatta, Laxmi; Rasheed, Humaira; Zhang, He; Kang, Hyun Min; Hornsby, Whitney; Moksnes, Marta Riise; Coward, Eivind; Melbye, Mads; Giskeødegård, Guro F.; Fenstad, Jørn; Krokstad, Steinar; Næss, Marit; Langhammer, Arnulf; Boehnke, Michael; Abecasis, Gonçalo R.; Åsvold, Bjørn Olav; Hveem, Kristian; Willer, Cristen J.
In: Cell Genomics, Vol. 2, No. 10, 100193, 2022.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - The HUNT study
T2 - A population-based cohort for genetic research
AU - Brumpton, Ben M.
AU - Graham, Sarah
AU - Surakka, Ida
AU - Skogholt, Anne Heidi
AU - Løset, Mari
AU - Fritsche, Lars G.
AU - Wolford, Brooke
AU - Zhou, Wei
AU - Nielsen, Jonas Bille
AU - Holmen, Oddgeir L.
AU - Gabrielsen, Maiken E.
AU - Thomas, Laurent
AU - Bhatta, Laxmi
AU - Rasheed, Humaira
AU - Zhang, He
AU - Kang, Hyun Min
AU - Hornsby, Whitney
AU - Moksnes, Marta Riise
AU - Coward, Eivind
AU - Melbye, Mads
AU - Giskeødegård, Guro F.
AU - Fenstad, Jørn
AU - Krokstad, Steinar
AU - Næss, Marit
AU - Langhammer, Arnulf
AU - Boehnke, Michael
AU - Abecasis, Gonçalo R.
AU - Åsvold, Bjørn Olav
AU - Hveem, Kristian
AU - Willer, Cristen J.
N1 - Publisher Copyright: © 2022 The Author(s)
PY - 2022
Y1 - 2022
N2 - The Trøndelag Health Study (HUNT) is a population-based cohort of ∼229,000 individuals recruited in four waves beginning in 1984 in Trøndelag County, Norway. Approximately 88,000 of these individuals have available genetic data from array genotyping. HUNT participants were recruited during four community-based recruitment waves and provided information on health-related behaviors, self-reported diagnoses, family history of disease, and underwent physical examinations. Linkage via the Norwegian personal identification number integrates digitized health care information from doctor visits and national health registries including death, cancer and prescription registries. Genome-wide association studies of HUNT participants have provided insights into the mechanism of cardiovascular, metabolic, osteoporotic, and liver-related diseases, among others. Unique features of this cohort that facilitate research include nearly 40 years of longitudinal follow-up in a motivated and well-educated population, family data, comprehensive phenotyping, and broad availability of DNA, RNA, urine, fecal, plasma, and serum samples.
AB - The Trøndelag Health Study (HUNT) is a population-based cohort of ∼229,000 individuals recruited in four waves beginning in 1984 in Trøndelag County, Norway. Approximately 88,000 of these individuals have available genetic data from array genotyping. HUNT participants were recruited during four community-based recruitment waves and provided information on health-related behaviors, self-reported diagnoses, family history of disease, and underwent physical examinations. Linkage via the Norwegian personal identification number integrates digitized health care information from doctor visits and national health registries including death, cancer and prescription registries. Genome-wide association studies of HUNT participants have provided insights into the mechanism of cardiovascular, metabolic, osteoporotic, and liver-related diseases, among others. Unique features of this cohort that facilitate research include nearly 40 years of longitudinal follow-up in a motivated and well-educated population, family data, comprehensive phenotyping, and broad availability of DNA, RNA, urine, fecal, plasma, and serum samples.
KW - big data
KW - biobank
KW - cardiovascular health
KW - complex disease
KW - electronic health records
KW - genetic epidemiology
KW - genetics
KW - longitudinal
KW - omics
KW - public health
U2 - 10.1016/j.xgen.2022.100193
DO - 10.1016/j.xgen.2022.100193
M3 - Journal article
C2 - 36777998
AN - SCOPUS:85140027872
VL - 2
JO - Cell Genomics
JF - Cell Genomics
SN - 2666-979x
IS - 10
M1 - 100193
ER -
ID: 334988705