Risk for depression and anxiety in long-term survivors of hematologic cancer
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Risk for depression and anxiety in long-term survivors of hematologic cancer. / Kuba, Katharina; Esser, Peter; Mehnert, Anja; Hinz, Andreas; Johansen, Christoffer; Lordick, Florian; Götze, Heide.
In: Health Psychology, Vol. 38, No. 3, 03.2019, p. 187-195.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Risk for depression and anxiety in long-term survivors of hematologic cancer
AU - Kuba, Katharina
AU - Esser, Peter
AU - Mehnert, Anja
AU - Hinz, Andreas
AU - Johansen, Christoffer
AU - Lordick, Florian
AU - Götze, Heide
PY - 2019/3
Y1 - 2019/3
N2 - OBJECTIVE: An increasing number of hematologic cancer patients outlive 10 years past diagnosis. Nevertheless, few studies investigated psychological strain in this patient group beyond 5 years after diagnosis. We conducted a registry-based investigation of risk for depression and anxiety among long-term hematologic cancer survivors up to 26 years after diagnosis compared to the general population.METHODS: In this cross-sectional postal survey, cancer survivors were recruited through 2 regional cancer registries in Germany. Depression (Patient Health Questionnaire-9) and anxiety (Generalized Anxiety Disorder-7) were assessed. Survivor data were compared to age- and gender-matched comparison groups (CG) randomly drawn from large representative samples (N > 5,000).RESULTS: Out of 2,001 eligible patients, 46% participated (n = 922). Survivors were significantly more likely than the CG to report elevated depressive (relative risk [RR] = 3.1; 95% confidence interval [CI]: 2.2-4.3) and anxious symptomatology (RR = 1.7; 95% CI: 1.2-2.3). Depression scores remained high even in the survivor Group 12-26 years after diagnosis. RR for anxiety decreased to values comparable to the CG. Younger and middle-aged survivors (≤65 years) were at highest relative and absolute risk to be psychologically impaired.CONCLUSION: This study shows that depression rather than anxiety is a prominent problem in long-term survivors of hematologic cancer. The results stress the importance of monitoring patients even years after diagnosing and supplying psychosocial support to patients in need. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
AB - OBJECTIVE: An increasing number of hematologic cancer patients outlive 10 years past diagnosis. Nevertheless, few studies investigated psychological strain in this patient group beyond 5 years after diagnosis. We conducted a registry-based investigation of risk for depression and anxiety among long-term hematologic cancer survivors up to 26 years after diagnosis compared to the general population.METHODS: In this cross-sectional postal survey, cancer survivors were recruited through 2 regional cancer registries in Germany. Depression (Patient Health Questionnaire-9) and anxiety (Generalized Anxiety Disorder-7) were assessed. Survivor data were compared to age- and gender-matched comparison groups (CG) randomly drawn from large representative samples (N > 5,000).RESULTS: Out of 2,001 eligible patients, 46% participated (n = 922). Survivors were significantly more likely than the CG to report elevated depressive (relative risk [RR] = 3.1; 95% confidence interval [CI]: 2.2-4.3) and anxious symptomatology (RR = 1.7; 95% CI: 1.2-2.3). Depression scores remained high even in the survivor Group 12-26 years after diagnosis. RR for anxiety decreased to values comparable to the CG. Younger and middle-aged survivors (≤65 years) were at highest relative and absolute risk to be psychologically impaired.CONCLUSION: This study shows that depression rather than anxiety is a prominent problem in long-term survivors of hematologic cancer. The results stress the importance of monitoring patients even years after diagnosing and supplying psychosocial support to patients in need. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
KW - Adolescent
KW - Adult
KW - Aged
KW - Aged, 80 and over
KW - Anxiety/psychology
KW - Anxiety Disorders/epidemiology
KW - Cancer Survivors/statistics & numerical data
KW - Cross-Sectional Studies
KW - Depression/psychology
KW - Depressive Disorder/epidemiology
KW - Female
KW - Germany
KW - Hematologic Neoplasms/pathology
KW - Humans
KW - Male
KW - Middle Aged
KW - Prevalence
KW - Registries
KW - Risk Factors
KW - Young Adult
U2 - 10.1037/hea0000713
DO - 10.1037/hea0000713
M3 - Journal article
C2 - 30762398
VL - 38
SP - 187
EP - 195
JO - Health Psychology
JF - Health Psychology
SN - 0278-6133
IS - 3
ER -
ID: 234701263