Plasma tissue inhibitor of metalloproteinases-1 as a biological marker? Pre-analytical considerations
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Tissue Inhibitor of Metalloproteinases-1 (TIMP-1) may be a valuable biological marker in Colorectal Cancer (CRC). However, prospective validation of TIMP-1 as a biological marker should include a series of pre-analytical considerations. TIMP-1 is stored in platelets, which may degranulate during collection and storage. The aim of this study was to evaluate the influence of platelet TIMP-1 contamination on plasma TIMP-1 levels in healthy volunteers.
Original language | English |
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Journal | Clinica Chimica Acta |
Volume | 380 |
Issue number | 1-2 |
Pages (from-to) | 128-32 |
Number of pages | 5 |
ISSN | 0009-8981 |
DOIs | |
Publication status | Published - 2007 |
ID: 34088844