Persistent wound drainage after tumor resection and endoprosthetic reconstruction of the proximal femur
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Persistent wound drainage after tumor resection and endoprosthetic reconstruction of the proximal femur. / Hettwer, Werner H; Horstmann, Peter F; Grum-Schwensen, Tomas A; Petersen, Michael M.
In: The Open Orthopaedics Journal, Vol. 8, 2014, p. 475-481.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Persistent wound drainage after tumor resection and endoprosthetic reconstruction of the proximal femur
AU - Hettwer, Werner H
AU - Horstmann, Peter F
AU - Grum-Schwensen, Tomas A
AU - Petersen, Michael M
PY - 2014
Y1 - 2014
N2 - PURPOSE: To examine the prevalence of prolonged wound drainage (PWD) after tumor resection and endoprosthetic reconstruction of the hip.METHODS: Retrospective review of 86 consecutive patients with metastatic bone disease, malignant hematologic bone disease or bone sarcoma, treated with tumor resection and subsequent endoprosthetic reconstruction of the proximal femur, between 2010 and 2012, in a single center.RESULTS: PWD for 7 days or more was observed in 41 cases (48%). The wounds only ceased oozing after a mean of 8.4 days, leading to prolonged administration of prophylactic antibiotics (mean 8.7 days) and length of hospital stay (mean 10.2 days). Total femur replacement, bone sarcoma and additional pelvic reconstruction were identified as significant independent risk factors for an even longer duration of PWD.CONCLUSION: Compared to conventional hip arthroplasty, PWD appears to be significantly more prevalent in patients undergoing tumor arthroplasty procedures of the hip. Given the potentially increased risk for periprosthetic joint infection (PJI), increased awareness, identification and implementation of adequate strategies for prevention and treatment of this avoidable complication are warranted.
AB - PURPOSE: To examine the prevalence of prolonged wound drainage (PWD) after tumor resection and endoprosthetic reconstruction of the hip.METHODS: Retrospective review of 86 consecutive patients with metastatic bone disease, malignant hematologic bone disease or bone sarcoma, treated with tumor resection and subsequent endoprosthetic reconstruction of the proximal femur, between 2010 and 2012, in a single center.RESULTS: PWD for 7 days or more was observed in 41 cases (48%). The wounds only ceased oozing after a mean of 8.4 days, leading to prolonged administration of prophylactic antibiotics (mean 8.7 days) and length of hospital stay (mean 10.2 days). Total femur replacement, bone sarcoma and additional pelvic reconstruction were identified as significant independent risk factors for an even longer duration of PWD.CONCLUSION: Compared to conventional hip arthroplasty, PWD appears to be significantly more prevalent in patients undergoing tumor arthroplasty procedures of the hip. Given the potentially increased risk for periprosthetic joint infection (PJI), increased awareness, identification and implementation of adequate strategies for prevention and treatment of this avoidable complication are warranted.
U2 - 10.2174/1874325001408010475
DO - 10.2174/1874325001408010475
M3 - Journal article
C2 - 25621083
VL - 8
SP - 475
EP - 481
JO - The Open Orthopaedics Journal
JF - The Open Orthopaedics Journal
SN - 1874-3250
ER -
ID: 137368565