Persistent idiopathic facial pain: a prospective systematic study of clinical characteristics and neuroanatomical findings at 3.0 Tesla MRI
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Persistent idiopathic facial pain : a prospective systematic study of clinical characteristics and neuroanatomical findings at 3.0 Tesla MRI. / Maarbjerg, Stine; Wolfram, Frauke; Heinskou, Tone Bruvik; Rochat, Per; Gozalov, Aydin; Brennum, Jannick; Olesen, Jes; Bendtsen, Lars.
In: Cephalalgia, Vol. 37, No. 13, 2017, p. 1231-1240.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Persistent idiopathic facial pain
T2 - a prospective systematic study of clinical characteristics and neuroanatomical findings at 3.0 Tesla MRI
AU - Maarbjerg, Stine
AU - Wolfram, Frauke
AU - Heinskou, Tone Bruvik
AU - Rochat, Per
AU - Gozalov, Aydin
AU - Brennum, Jannick
AU - Olesen, Jes
AU - Bendtsen, Lars
PY - 2017
Y1 - 2017
N2 - Introduction: Persistent idiopathic facial pain (PIFP) is a poorly understood chronic orofacial pain disorder and a differential diagnosis to trigeminal neuralgia. To address the lack of systematic studies in PIFP we here report clinical characteristics and neuroimaging findings in PIFP. Methods: Data collection was prospective and standardized in consecutive PIFP patients. All patients underwent 3.0 MRI. Results: In a cohort of 53 PIFP patients, the average age of onset was 44.1 years. PIFP was found in more women 40 (75%) than men 13 (25%), p < 0.001. There was a high prevalence of bilateral pain 7 (13%), hypoesthesia 23 (48%), depression 16 (30%) and other chronic pain conditions 17 (32%) and a low prevalence of stabbing pain 21 (40%), touch-evoked pain 14 (26%) and remission periods 10 (19%). The odds ratio between neurovascular contact and the painful side was 1.4 (95% Cl 0.4–4.4, p = 0.565) and the odds ratio between neurovascular contact with displacement of the trigeminal nerve and the painful side was 0.2 (95% Cl 0.0–2.1, p = 0.195). Conclusion: PIFP is separated from trigeminal neuralgia both with respect to the clinical characteristics and neuroimaging findings, as NVC was not associated to PIFP.
AB - Introduction: Persistent idiopathic facial pain (PIFP) is a poorly understood chronic orofacial pain disorder and a differential diagnosis to trigeminal neuralgia. To address the lack of systematic studies in PIFP we here report clinical characteristics and neuroimaging findings in PIFP. Methods: Data collection was prospective and standardized in consecutive PIFP patients. All patients underwent 3.0 MRI. Results: In a cohort of 53 PIFP patients, the average age of onset was 44.1 years. PIFP was found in more women 40 (75%) than men 13 (25%), p < 0.001. There was a high prevalence of bilateral pain 7 (13%), hypoesthesia 23 (48%), depression 16 (30%) and other chronic pain conditions 17 (32%) and a low prevalence of stabbing pain 21 (40%), touch-evoked pain 14 (26%) and remission periods 10 (19%). The odds ratio between neurovascular contact and the painful side was 1.4 (95% Cl 0.4–4.4, p = 0.565) and the odds ratio between neurovascular contact with displacement of the trigeminal nerve and the painful side was 0.2 (95% Cl 0.0–2.1, p = 0.195). Conclusion: PIFP is separated from trigeminal neuralgia both with respect to the clinical characteristics and neuroimaging findings, as NVC was not associated to PIFP.
KW - atypical facial pain
KW - clinical characteristics
KW - neuroimaging
KW - orofacial pain
KW - Persistent idiopathic facial pain
U2 - 10.1177/0333102416675618
DO - 10.1177/0333102416675618
M3 - Journal article
C2 - 27789649
AN - SCOPUS:85033432901
VL - 37
SP - 1231
EP - 1240
JO - Cephalalgia
JF - Cephalalgia
SN - 0800-1952
IS - 13
ER -
ID: 189702561