Novel understanding of self-reactive T cells

Research output: Contribution to journalEditorialResearchpeer-review

In a recent issue of Immunity, Mark Davis and colleagues describe that thymic selection does not eliminate but prunes self-reactive T cell clones. Self-reactive T cells are a natural part of the T-cell repertoire and may be important in the fight against pathogens in addition to being important immune regulators.

Original languageEnglish
Article numbere1083672
JournalOncoImmunology
Volume5
Issue number3
Number of pages2
ISSN2162-4011
DOIs
Publication statusPublished - Mar 2016

    Research areas

  • Anti-Tregs, CD8, IDO, PD-L1, self-reactive T cells, thymic selection

ID: 180937487