NOD2/CARD15 genotype, cardiovascular disease and cancer in 43,600 individuals from the general population
Research output: Contribution to journal › Journal article › Research › peer-review
The NOD2/CARD15 gene is involved in the innate immune response, and thus in inflammation. Three polymorphisms in this gene (Arg702Trp rs2066844, Gly908Arg rs2066845 and Leu1007fsinsC rs5743293) have been associated with increased risk of the inflammatory bowel disease, the Crohn's disease. We tested whether these polymorphisms are also associated with increased risk of cardiovascular disease and cancer, in which the innate immune system and inflammation may influence pathogenesis.
Original language | English |
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Journal | The Egyptian Journal of Internal Medicine |
Volume | 268 |
Issue number | 2 |
Pages (from-to) | 162-70 |
Number of pages | 9 |
ISSN | 1110-7782 |
DOIs | |
Publication status | Published - Aug 2010 |
ID: 48538453