New insights into the diagnosis of hidradenitis suppurativa: Clinical presentations and phenotypes

Research output: Contribution to journalJournal articleResearchpeer-review

Current classifications for hidradenitis suppurativa (HS), such as the Hurley staging system, are not very specific. The absence of rigorous classifications is incongruous with the clinical variability of the condition. There is no pathognomonic sign for HS that leads to a diagnosis that is unquestionable. Consequently, diagnosis is made largely through clinical presentation of the condition. The use of several validated tools assists in confirming the diagnosis and the severity of the disease. In future investigations, the identification of phenotypes and clinical subtypes--taking into account genetic variants--will serve to identify subpopulations of patients who are responsive to particular therapies, thereby improving the overall therapeutic picture for patients with HS. There is a potential for personalized, tailored delivery of therapy in the HS setting.

Original languageEnglish
JournalJournal of the American Academy of Dermatology
Volume73
Issue number5 Suppl 1
Pages (from-to)S23-6
ISSN0190-9622
DOIs
Publication statusPublished - Nov 2015

    Research areas

  • Adult, Anti-Infective Agents, Anti-Inflammatory Agents, Biopsy, Needle, Female, Genetic Predisposition to Disease, Hidradenitis Suppurativa, Humans, Immunohistochemistry, Male, Phenotype, Sensitivity and Specificity, Severity of Illness Index, Treatment Outcome, Young Adult, Comparative Study, Journal Article, Review

ID: 179171766