Methylprednisolone in combination with interferon beta-1a for relapsing-remitting multiple sclerosis (MECOMBIN study): a multicentre, double-blind, randomised, placebo-controlled, parallel-group trial

Research output: Contribution to journalJournal articleResearchpeer-review

  • Mads Ravnborg
  • Sørensen, Per Soelberg
  • Magnus Andersson
  • Elisabeth G Celius
  • Peter J Jongen
  • Irina Elovaara
  • Emmanuel Bartholomé
  • Cris S Constantinescu
  • Karsten Beer
  • Ellen Garde
  • Bjørn Sperling
Interferon beta is commonly used to treat patients with relapsing-remitting multiple sclerosis; however, the treatment is only partially effective in reducing relapses and progression of disability. Corticosteroids are used to treat relapses in patients with multiple sclerosis. We therefore aimed to investigate the combination of cyclic methylprednisolone and interferon beta for the treatment of relapsing-remitting multiple sclerosis.
Original languageEnglish
JournalLancet Neurology
Volume9
Issue number7
Pages (from-to)672-80
Number of pages9
ISSN1474-4422
DOIs
Publication statusPublished - 1 Jul 2010

ID: 34093085