Mannose-Binding Lectin Deficiency Is Associated with Myocardial Infarction: The HUNT2 Study in Norway
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Mannose-Binding Lectin Deficiency Is Associated with Myocardial Infarction : The HUNT2 Study in Norway. / Vengen, Inga Thorsen; Madsen, Hans O; Garred, Peter; Platou, Carl; Vatten, Lars; Videm, Vibeke.
In: P L o S One, Vol. 7, No. 7, 2012, p. e42113.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Mannose-Binding Lectin Deficiency Is Associated with Myocardial Infarction
T2 - The HUNT2 Study in Norway
AU - Vengen, Inga Thorsen
AU - Madsen, Hans O
AU - Garred, Peter
AU - Platou, Carl
AU - Vatten, Lars
AU - Videm, Vibeke
PY - 2012
Y1 - 2012
N2 - Mannose-binding lectin (MBL) and ficolins activate the complement cascade, which is involved in atherogenesis. Based on a pilot study, we hypothesized that functional polymorphisms in the MBL gene (MBL2) leading to dysfunctional protein are related to development of myocardial infarction (MI). The aim of the present study was to study polymorphisms in MBL2 and ficolin genes in relation to the risk of MI.
AB - Mannose-binding lectin (MBL) and ficolins activate the complement cascade, which is involved in atherogenesis. Based on a pilot study, we hypothesized that functional polymorphisms in the MBL gene (MBL2) leading to dysfunctional protein are related to development of myocardial infarction (MI). The aim of the present study was to study polymorphisms in MBL2 and ficolin genes in relation to the risk of MI.
U2 - 10.1371/journal.pone.0042113
DO - 10.1371/journal.pone.0042113
M3 - Journal article
C2 - 22848725
VL - 7
SP - e42113
JO - PLoS ONE
JF - PLoS ONE
SN - 1932-6203
IS - 7
ER -
ID: 48448976