Langt QT-syndrom--gener, mekanismer og risici. Indikation for genetisk familieudredning?
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Langt QT-syndrom--gener, mekanismer og risici. Indikation for genetisk familieudredning? / Bundgaard, Henning; Havndrup, Ole; Christiansen, Michael; Andersen, Paal Skytt; Jensen, Henrik Kjaerulff; Svendsen, Jesper Hastrup; Kjeldsen, Keld P.
In: Ugeskrift for læger, Vol. 168, No. 26-32, 2006, p. 2537-42.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Langt QT-syndrom--gener, mekanismer og risici. Indikation for genetisk familieudredning?
AU - Bundgaard, Henning
AU - Havndrup, Ole
AU - Christiansen, Michael
AU - Andersen, Paal Skytt
AU - Jensen, Henrik Kjaerulff
AU - Svendsen, Jesper Hastrup
AU - Kjeldsen, Keld P
N1 - Keywords: Death, Sudden, Cardiac; Genetic Predisposition to Disease; Genetic Testing; Humans; Ion Channels; Long QT Syndrome; Risk Factors; Syncope
PY - 2006
Y1 - 2006
N2 - Inherited long QT syndrome (LQTS) is a cardiac disease characterised by episodes of ventricular tachyarrhythmia, presenting as syncope or sudden death. Untreated, the annual mortality rate is 1-2%. Sudden death has been reported as the first manifestation of the disease in some cases. Therefore, early (pre-symptomatic) diagnosis and management may save lives. However, clinically false negative relatives are also at risk of sudden death. On this basis we conclude assessment of relatives should be extended with genetic testing. Udgivelsesdato: 2006-Jun-26
AB - Inherited long QT syndrome (LQTS) is a cardiac disease characterised by episodes of ventricular tachyarrhythmia, presenting as syncope or sudden death. Untreated, the annual mortality rate is 1-2%. Sudden death has been reported as the first manifestation of the disease in some cases. Therefore, early (pre-symptomatic) diagnosis and management may save lives. However, clinically false negative relatives are also at risk of sudden death. On this basis we conclude assessment of relatives should be extended with genetic testing. Udgivelsesdato: 2006-Jun-26
M3 - Tidsskriftartikel
C2 - 16824406
VL - 168
SP - 2537
EP - 2542
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 26-32
ER -
ID: 21258917