Kateterbaseret aortaklapsubstitution. Initiale erfaringer med implantation af stentklap
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Kateterbaseret aortaklapsubstitution. Initiale erfaringer med implantation af stentklap. / Nielsen, Hans Henrik Møller; Andersen, Henning Rud; Hjortdal, Vibeke Elisabeth; Klaaborg, Kaj-Erik; Jakobsen, Carl-Johan; Egeblad, Henrik; Terp, Kim; Lindskov, Christian; Sloth, Erik; Poulsen, Steen Hvidtfeldt; Bøing, Ingeborg; Thuesen, Leif.
In: Ugeskrift for Laeger, Vol. 171, No. 33, 10.08.2009, p. 2277-81.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Kateterbaseret aortaklapsubstitution. Initiale erfaringer med implantation af stentklap
AU - Nielsen, Hans Henrik Møller
AU - Andersen, Henning Rud
AU - Hjortdal, Vibeke Elisabeth
AU - Klaaborg, Kaj-Erik
AU - Jakobsen, Carl-Johan
AU - Egeblad, Henrik
AU - Terp, Kim
AU - Lindskov, Christian
AU - Sloth, Erik
AU - Poulsen, Steen Hvidtfeldt
AU - Bøing, Ingeborg
AU - Thuesen, Leif
PY - 2009/8/10
Y1 - 2009/8/10
N2 - INTRODUCTION: Recent years have seen the introduction of catheter-based aortic valve substitution with stent valves to treat aortic valve stenosis in patients who were deemed inoperable via conventional open heart surgery. We here report our initial experience.MATERIAL AND METHODS: Register-based study with prospective registration of prespecified parameters. A total of 26 patients were treated with an aortic stent valve, 12 via transfemoral (TFA-AVI) and 14 via transapical (TAP-AVI) access. In the TFA-AVI group, 75% were women and the average age was 85 4.5 years; in the TAP-AVI group, 71% were women and the average age was 79 8.4 years.RESULTS: In the TFA-AVI group, successful stent valve implantation was performed in 9/12 (75%) and TAP-AVI in 13/14 (93%) patients. Mortality after 30 days was 25% in the TFA-AVI and 7% in the TAP-AVI group. The aortic valve area increased from 0.6 0.13 cm(2) to 1.6 0.39 (2) in the TFA-AVI group and from 0.7 0.2 (2) to 1.6 0.37 (2) in the TAP-AVI group. 91% of patients showed clinical improvement after treatment.CONCLUSION: Transcatheter aortic valve implantation of conventional unresectable patients requires close cooperation between different specialities. The treatment seems to be a realistic alternative to medical treatment for inoperable patients and may even be used in operable high-risk patients.
AB - INTRODUCTION: Recent years have seen the introduction of catheter-based aortic valve substitution with stent valves to treat aortic valve stenosis in patients who were deemed inoperable via conventional open heart surgery. We here report our initial experience.MATERIAL AND METHODS: Register-based study with prospective registration of prespecified parameters. A total of 26 patients were treated with an aortic stent valve, 12 via transfemoral (TFA-AVI) and 14 via transapical (TAP-AVI) access. In the TFA-AVI group, 75% were women and the average age was 85 4.5 years; in the TAP-AVI group, 71% were women and the average age was 79 8.4 years.RESULTS: In the TFA-AVI group, successful stent valve implantation was performed in 9/12 (75%) and TAP-AVI in 13/14 (93%) patients. Mortality after 30 days was 25% in the TFA-AVI and 7% in the TAP-AVI group. The aortic valve area increased from 0.6 0.13 cm(2) to 1.6 0.39 (2) in the TFA-AVI group and from 0.7 0.2 (2) to 1.6 0.37 (2) in the TAP-AVI group. 91% of patients showed clinical improvement after treatment.CONCLUSION: Transcatheter aortic valve implantation of conventional unresectable patients requires close cooperation between different specialities. The treatment seems to be a realistic alternative to medical treatment for inoperable patients and may even be used in operable high-risk patients.
KW - Aged
KW - Aged, 80 and over
KW - Aortic Valve/surgery
KW - Bioprosthesis
KW - Cardiac Catheterization/methods
KW - Female
KW - Heart Valve Prosthesis
KW - Heart Valve Prosthesis Implantation/instrumentation
KW - Humans
KW - Male
KW - Prospective Studies
KW - Registries
KW - Stents
KW - Treatment Outcome
M3 - Tidsskriftartikel
C2 - 19732506
VL - 171
SP - 2277
EP - 2281
JO - Ugeskrift for Laeger
JF - Ugeskrift for Laeger
SN - 0041-5782
IS - 33
ER -
ID: 242714387