Is it safe to discontinue primary Pneumocystis jiroveci pneumonia prophylaxis in patients with virologically suppressed HIV infection and a CD4 cell count

Research output: Contribution to journalJournal articleResearchpeer-review

  • Amanda Mocroft
  • Peter Reiss
  • Kirk, Ole
  • Cristina Mussini
  • Enrico Girardi
  • Philippe Morlat
  • Christoph Stephan
  • Stephane De Wit
  • Katja Doerholt
  • Jade Ghosn
  • Heiner C Bucher
  • Lundgren, Jens
  • Genevieve Chene
  • Jose M Miro
  • Hansjakob Furrer
  • Opportunistic Infections Project Team of the Collaboration of Observational HIV Epidemiological Research in Europe (COHERE)
Current guidelines suggest that primary prophylaxis for Pneumocystis jiroveci pneumonia (PcP) can be safely stopped in human immunodeficiency virus (HIV)-infected patients who are receiving combined antiretroviral therapy (cART) and who have a CD4 cell count >200 cells/microL. There are few data regarding the incidence of PcP or safety of stopping prophylaxis in virologically suppressed patients with CD4 cell counts of 101-200 cells/microL.
Original languageEnglish
JournalClinical Infectious Diseases
Volume51
Issue number5
Pages (from-to)611-9
Number of pages9
ISSN1058-4838
DOIs
Publication statusPublished - 1 Sep 2010

    Research areas

  • AIDS-Related Opportunistic Infections, Adult, Anti-HIV Agents, Antifungal Agents, CD4 Lymphocyte Count, Europe, Female, HIV Infections, Humans, Incidence, Male, Middle Aged, Pneumocystis jirovecii, Pneumonia, Pneumocystis, Risk Factors

ID: 33863666