International Society for Heart and Lung Transplantation consensus statement for the standardization of bronchoalveolar lavage in lung transplantation

Research output: Contribution to journalEditorialResearchpeer-review

  • Tereza Martinu
  • Angela Koutsokera
  • Christian Benden
  • Edward Cantu
  • Daniel Chambers
  • Marcelo Cypel
  • Jeffrey Edelman
  • Amir Emtiazjoo
  • Andrew J. Fisher
  • John R. Greenland
  • Don Hayes
  • David Hwang
  • Brian C. Keller
  • Erika D. Lease
  • Perch, Michael
  • Masaaki Sato
  • Jamie L. Todd
  • Stijn Verleden
  • Jan von der Thüsen
  • S. Samuel Weigt
  • Shaf Keshavjee
  • Cecilia Chaparro
  • David Wilson Roe
  • Frank D'Ovidio
  • George Chaux
  • Greg Snell
  • Laurent Godinas
  • Mohamed Al-Aloul
  • Steven Hays
  • Jamie Todd
  • Amy Rigby
  • Louis Clauden
  • Matthew Morrell
  • Puneet Garcha
  • Sanjeev Raman
  • Soma Jyothula
  • Michael Trotter
  • Erika Lease
  • Cassie Kennedy
  • Chadi A. Hage
  • Saima Aslam
  • Shahid Husain
  • Katharina Wassilew
  • Reinaldo Rampolla-Selles
  • Siddhartha G. Kapnadak
  • Umesh Goswami
  • John Greenland
  • Aric Gregson
  • Bart Vanaudenaerde
  • Tji Gan
  • bronchoalveolar lavage standardization workgroup

Bronchoalveolar lavage (BAL) is a key clinical and research tool in lung transplantation (LTx). However, BAL collection and processing are not standardized across LTx centers. This International Society for Heart and Lung Transplantation–supported consensus document on BAL standardization aims to clarify definitions and propose common approaches to improve clinical and research practice standards. The following 9 areas are covered: (1) bronchoscopy procedure and BAL collection, (2) sample handling, (3) sample processing for microbiology, (4) cytology, (5) research, (6) microbiome, (7) sample inventory/tracking, (8) donor bronchoscopy, and (9) pediatric considerations. This consensus document aims to harmonize clinical and research practices for BAL collection and processing in LTx. The overarching goal is to enhance standardization and multicenter collaboration within the international LTx community and enable improvement and development of new BAL-based diagnostics.

Original languageEnglish
JournalJournal of Heart and Lung Transplantation
Volume39
Issue number11
Pages (from-to)1171-1190
Number of pages20
ISSN1053-2498
DOIs
Publication statusPublished - 2020

    Research areas

  • bronchial wash, bronchoalveolar lavage, donor bronchoscopy, lung transplantation, methodology, pediatric bronchoscopy, standardization

ID: 260250274