Increased risk of nonmelanoma skin cancer in patients with alpha-1 antitrypsin deficiency: A nationwide cohort study
Research output: Contribution to journal › Letter › Research › peer-review
α1-Antitrypsin deficiency causes emphysema, liver cirrhosis and hepatic cancer, and is also associated with a slightly increased risk of non-hepatic cancer.1 α1-Antitrypsin deficiency is known as a rare cause of panniculitis,2 but its relation to skin cancer is poorly described.3 We hypothesized that α1-antitrypsin deficiency is associated with increased risks of nonmelanoma and melanoma skin cancer. To test this hypothesis, we followed 2702 individuals with α1-antitrypsin deficiency and 26,750 control subjects without α1-antitrypsin deficiency matched by age, sex, and municipality in Denmark and recorded skin cancer as outcome during 62 years of follow-up
Original language | English |
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Journal | Journal of the European Academy of Dermatology and Venereology |
ISSN | 0926-9959 |
DOIs | |
Publication status | Accepted/In press - 2024 |
ID: 391777797