Improved cardiopulmonary exercise function after modified Nuss operation for pectus excavatum
Research output: Contribution to journal › Journal article › Research › peer-review
OBJECTIVES: Patients with pectus excavatum have compromised cardiac function during exercise. We hypothesized that the Nuss technique would improve cardiopulmonary function during exercise.
METHODS: We investigated 75 teenagers (49 patients and 26 controls) at rest and during bicycle exercise prior to surgery and 1 year postoperative.
RESULTS: Prior to surgery, patients had a lower cardiac index 6.6 ± 1.1 l/min/m(2) when compared with controls 8.1 ± 1.0 l/min/m(2) during submaximal exercise, P = 0.0001. There was no difference in heart rate or increase in heart rate between the two groups. One year after surgery, cardiac index had significantly increased in the pectus group, P = 0.0054 although cardiac index was still significantly lower 7.2 ± 1.0 l/min/m(2) when compared with the control subjects (8.5 ± 1.6 l/min/m(2), P = 0.0008). Both the patients and the controls increased their VO(2) max during the one-year study period although the controls increased most. Right ventricular diastolic dimension increased in both groups over the one-year study period and left ventricular dimensions increased in the patients. Before operation, the patients had lower forced expiratory capacity FEV(1) 86 ± 13% when compared with controls 94 ± 10%, P = 0.009. Patients increased FEV(1)/forced vital capacity over the one-year long study course although there were no differences between groups.
CONCLUSION: Patients with pectus excavatum have lower cardiac index at submaximal exercise when compared with healthy age-matched controls. Their cardiac index and FEV(1) are increased one year after the modified Nuss operation.
Original language | English |
---|---|
Journal | European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery |
Volume | 41 |
Issue number | 5 |
Pages (from-to) | 1063-7 |
Number of pages | 5 |
ISSN | 1010-7940 |
DOIs | |
Publication status | Published - May 2012 |
- Adolescent, Cardiac Output/physiology, Case-Control Studies, Exercise Test/methods, Forced Expiratory Volume/physiology, Funnel Chest/diagnostic imaging, Heart Rate/physiology, Humans, Minimally Invasive Surgical Procedures/methods, Oxygen Consumption/physiology, Postoperative Period, Spirometry/methods, Treatment Outcome, Ultrasonography, Vital Capacity/physiology
Research areas
ID: 242614000