Identifying QTL and genetic correlations between fur quality traits in mink (Neovison vison)
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Identifying QTL and genetic correlations between fur quality traits in mink (Neovison vison). / Thirstrup, Janne Pia; Anistoroaei, Razvan Marian; Guldbrandtsen, Bernt; Christensen, Knud Arnbjerg; Fredholm, Merete; Nielsen, V. H.
In: Animal Genetics, Vol. 45, No. 1, 2014, p. 105-110.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Identifying QTL and genetic correlations between fur quality traits in mink (Neovison vison)
AU - Thirstrup, Janne Pia
AU - Anistoroaei, Razvan Marian
AU - Guldbrandtsen, Bernt
AU - Christensen, Knud Arnbjerg
AU - Fredholm, Merete
AU - Nielsen, V. H.
PY - 2014
Y1 - 2014
N2 - Mapping of QTL affecting fur quality traits (guard hair length, guard hair thickness, density of wool, surface of the fur and quality) and skin length was performed in a three-generation mink population (F design). In the parental generation, Nordic Brown mink were crossed reciprocally with American Black short nap mink. In all, 1082 mink encompassing three generations were used for the analyses. The mink were genotyped for 104 microsatellites covering all 14 autosomes. The QTL analyses were performed by least-square regression implemented in gridqtl software. Genetic and phenotypic correlations and heritabilities were estimated using the average information-restricted maximum-likelihood method. Evidence was found for QTL affecting fur quality traits on nine autosomes. QTL were detected for guard hair thickness on chromosomes 1, 2, 3, 6 and 13; for guard hair length on chromosomes 2, 3 and 6; for wool density on chromosomes 6 and 13; for surface on chromosomes 7, 12 and 13; for quality on chromosomes 6, 7, 11 and 13; and for skin length on chromosomes 7 and 9. Proximity of locations of QTL for guard hair length, guard hair thickness and for wool density and quality suggests that some of the traits are in part under the influence of the same genes. Traits under the influence of QTL at close or identical positions also were traits that were strongly genotypically correlated. Based on the results of correlation analyses, the most important single traits influencing the quality were found to be density of wool, guard hair thickness and appearance of the surface.
AB - Mapping of QTL affecting fur quality traits (guard hair length, guard hair thickness, density of wool, surface of the fur and quality) and skin length was performed in a three-generation mink population (F design). In the parental generation, Nordic Brown mink were crossed reciprocally with American Black short nap mink. In all, 1082 mink encompassing three generations were used for the analyses. The mink were genotyped for 104 microsatellites covering all 14 autosomes. The QTL analyses were performed by least-square regression implemented in gridqtl software. Genetic and phenotypic correlations and heritabilities were estimated using the average information-restricted maximum-likelihood method. Evidence was found for QTL affecting fur quality traits on nine autosomes. QTL were detected for guard hair thickness on chromosomes 1, 2, 3, 6 and 13; for guard hair length on chromosomes 2, 3 and 6; for wool density on chromosomes 6 and 13; for surface on chromosomes 7, 12 and 13; for quality on chromosomes 6, 7, 11 and 13; and for skin length on chromosomes 7 and 9. Proximity of locations of QTL for guard hair length, guard hair thickness and for wool density and quality suggests that some of the traits are in part under the influence of the same genes. Traits under the influence of QTL at close or identical positions also were traits that were strongly genotypically correlated. Based on the results of correlation analyses, the most important single traits influencing the quality were found to be density of wool, guard hair thickness and appearance of the surface.
UR - http://www.scopus.com/inward/record.url?scp=84889065695&partnerID=8YFLogxK
U2 - 10.1111/age.12102
DO - 10.1111/age.12102
M3 - Journal article
C2 - 24303917
VL - 45
SP - 105
EP - 110
JO - Animal Genetics
JF - Animal Genetics
SN - 0268-9146
IS - 1
ER -
ID: 91795687