Human migraine models

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Human migraine models. / Iversen, Helle Klingenberg.

In: Cephalalgia : an international journal of headache, Vol. 21, No. 7, 09.2001, p. 781-5.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Iversen, HK 2001, 'Human migraine models', Cephalalgia : an international journal of headache, vol. 21, no. 7, pp. 781-5.

APA

Iversen, H. K. (2001). Human migraine models. Cephalalgia : an international journal of headache, 21(7), 781-5.

Vancouver

Iversen HK. Human migraine models. Cephalalgia : an international journal of headache. 2001 Sep;21(7):781-5.

Author

Iversen, Helle Klingenberg. / Human migraine models. In: Cephalalgia : an international journal of headache. 2001 ; Vol. 21, No. 7. pp. 781-5.

Bibtex

@article{3d8dba513fc545108d87853aff9fb7e0,
title = "Human migraine models",
abstract = "The need for experimental models is obvious. In animal models it is possible to study vascular responses, neurogenic inflammation, c-fos expression etc. However, the pathophysiology of migraine remains unsolved, why results from animal studies not directly can be related to the migraine attack, which is a human experience. A set-up for investigations of experimental headache and migraine in humans, has been evaluated and headache mechanisms explored by using nitroglycerin and other headache-inducing agents. Nitric oxide (NO) or other parts of the NO activated cascade seems to be responsible for the induced headache and migraine. Perspectives are discussed.",
keywords = "Animals, Cerebrovascular Circulation, Humans, Migraine Disorders, Models, Neurological, Nitroglycerin, Vasodilator Agents",
author = "Iversen, {Helle Klingenberg}",
year = "2001",
month = sep,
language = "English",
volume = "21",
pages = "781--5",
journal = "Cephalalgia",
issn = "0800-1952",
publisher = "SAGE Publications",
number = "7",

}

RIS

TY - JOUR

T1 - Human migraine models

AU - Iversen, Helle Klingenberg

PY - 2001/9

Y1 - 2001/9

N2 - The need for experimental models is obvious. In animal models it is possible to study vascular responses, neurogenic inflammation, c-fos expression etc. However, the pathophysiology of migraine remains unsolved, why results from animal studies not directly can be related to the migraine attack, which is a human experience. A set-up for investigations of experimental headache and migraine in humans, has been evaluated and headache mechanisms explored by using nitroglycerin and other headache-inducing agents. Nitric oxide (NO) or other parts of the NO activated cascade seems to be responsible for the induced headache and migraine. Perspectives are discussed.

AB - The need for experimental models is obvious. In animal models it is possible to study vascular responses, neurogenic inflammation, c-fos expression etc. However, the pathophysiology of migraine remains unsolved, why results from animal studies not directly can be related to the migraine attack, which is a human experience. A set-up for investigations of experimental headache and migraine in humans, has been evaluated and headache mechanisms explored by using nitroglycerin and other headache-inducing agents. Nitric oxide (NO) or other parts of the NO activated cascade seems to be responsible for the induced headache and migraine. Perspectives are discussed.

KW - Animals

KW - Cerebrovascular Circulation

KW - Humans

KW - Migraine Disorders

KW - Models, Neurological

KW - Nitroglycerin

KW - Vasodilator Agents

M3 - Journal article

C2 - 11595013

VL - 21

SP - 781

EP - 785

JO - Cephalalgia

JF - Cephalalgia

SN - 0800-1952

IS - 7

ER -

ID: 128983639