Genome-wide association study of follicular lymphoma identifies a risk locus at 6p21.32
Research output: Contribution to journal › Journal article › Research › peer-review
To identify susceptibility loci for non-Hodgkin lymphoma subtypes, we conducted a three-stage genome-wide association study. We identified two variants associated with follicular lymphoma at 6p21.32 (rs10484561, combined P = 1.12 × 10-29 and rs7755224, combined P = 2.00 × 10-19; r2 = 1.0), supporting the idea that major histocompatibility complex genetic variation influences follicular lymphoma susceptibility. We also found confirmatory evidence of a previously reported association between chronic lymphocytic leukemia/small lymphocytic lymphoma and rs735665 (combined P = 4.24 × 10-9).
Original language | English |
---|---|
Journal | Nature Genetics |
Volume | 42 |
Issue number | 8 |
Pages (from-to) | 661-664 |
Number of pages | 4 |
ISSN | 1061-4036 |
DOIs | |
Publication status | Published - Aug 2010 |
ID: 258216911