Functional health status late after surgical correction of aortic coarctation
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Functional health status late after surgical correction of aortic coarctation. / Pedersen, Thais Almeida Lins; Røpcke, Diana Mathilde; Hjortdal, Vibeke Elisabeth.
In: Congenital Heart Disease, Vol. 6, No. 6, 29.11.2011, p. 566-72.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Functional health status late after surgical correction of aortic coarctation
AU - Pedersen, Thais Almeida Lins
AU - Røpcke, Diana Mathilde
AU - Hjortdal, Vibeke Elisabeth
N1 - © 2011 Copyright the Authors. Congenital Heart Disease © 2011 Wiley Periodicals, Inc.
PY - 2011/11/29
Y1 - 2011/11/29
N2 - OBJECTIVES: To investigate functional health status among adults previously operated for aortic coarctation (CoA) compared with healthy subjects; to assess the influence of medication and exercise capacity on patients' functional health.DESIGN: Questionnaire-based investigation among 119 patients who underwent surgical repair of CoA during 1965-1985 and 36 age- and gender-matched healthy subjects using the SF-36 health survey. Original scores were transformed into norm-based scores, and summary scale scores were calculated. Exercise capacity was measured by symptom-limited bicycle ergometer testing.SETTING: Tertiary referral center.PATIENTS: Among 156 current survivors, 119 (74 males) participated in the study. Median age (range) at repair was 11 (0.1-40) years and 44 (26-72) years at follow-up.OUTCOME MEASURES: Comparison of all components of SF-36 survey between patients and controls, as well as within patients regarding use of cardiovascular medication and exercise capacity.RESULTS: Norm-based physical functioning scores were significantly lower among patients compared with controls (51.8 ± 7.1 vs. 54.3 ± 4.7, P < 0.05). Patients using antihypertensive medication scored significantly lower in all physical categories (physical component summary= 48.9 ± 10.4 vs. 54.9 ± 4.9, P < 0.05) as well as in vitality (46.4 ± 10.5 vs. 51.4 ± 10.4, P < 0.05). Patients with reduced exercise capacity scored significantly lower in several mental and physical categories compared with patients with normal exercise capacity (physical component summary= 49.7 ± 10.7 vs. 54.0 ± 6.2, P < 0.05; mental component summary= 44.9 ± 14.6 vs. 50.1 ± 10.0, P < 0.05).CONCLUSION: Functional health status in patients late after CoA repair is only slightly impaired when compared with controls. However, the subgroup with reduced exercise capacity and need for cardiovascular medications have significant impairment on both physical and mental aspects of functional health.
AB - OBJECTIVES: To investigate functional health status among adults previously operated for aortic coarctation (CoA) compared with healthy subjects; to assess the influence of medication and exercise capacity on patients' functional health.DESIGN: Questionnaire-based investigation among 119 patients who underwent surgical repair of CoA during 1965-1985 and 36 age- and gender-matched healthy subjects using the SF-36 health survey. Original scores were transformed into norm-based scores, and summary scale scores were calculated. Exercise capacity was measured by symptom-limited bicycle ergometer testing.SETTING: Tertiary referral center.PATIENTS: Among 156 current survivors, 119 (74 males) participated in the study. Median age (range) at repair was 11 (0.1-40) years and 44 (26-72) years at follow-up.OUTCOME MEASURES: Comparison of all components of SF-36 survey between patients and controls, as well as within patients regarding use of cardiovascular medication and exercise capacity.RESULTS: Norm-based physical functioning scores were significantly lower among patients compared with controls (51.8 ± 7.1 vs. 54.3 ± 4.7, P < 0.05). Patients using antihypertensive medication scored significantly lower in all physical categories (physical component summary= 48.9 ± 10.4 vs. 54.9 ± 4.9, P < 0.05) as well as in vitality (46.4 ± 10.5 vs. 51.4 ± 10.4, P < 0.05). Patients with reduced exercise capacity scored significantly lower in several mental and physical categories compared with patients with normal exercise capacity (physical component summary= 49.7 ± 10.7 vs. 54.0 ± 6.2, P < 0.05; mental component summary= 44.9 ± 14.6 vs. 50.1 ± 10.0, P < 0.05).CONCLUSION: Functional health status in patients late after CoA repair is only slightly impaired when compared with controls. However, the subgroup with reduced exercise capacity and need for cardiovascular medications have significant impairment on both physical and mental aspects of functional health.
KW - Adolescent
KW - Adult
KW - Aged
KW - Aortic Coarctation/complications
KW - Cardiac Surgical Procedures
KW - Cardiovascular Agents/therapeutic use
KW - Case-Control Studies
KW - Child
KW - Child, Preschool
KW - Denmark
KW - Emotions
KW - Exercise Test
KW - Exercise Tolerance
KW - Female
KW - Health Status
KW - Humans
KW - Infant
KW - Linear Models
KW - Male
KW - Mental Health
KW - Middle Aged
KW - Multivariate Analysis
KW - Quality of Life
KW - Social Behavior
KW - Surveys and Questionnaires
KW - Survivors
KW - Time Factors
KW - Treatment Outcome
KW - Young Adult
U2 - 10.1111/j.1747-0803.2011.00595.x
DO - 10.1111/j.1747-0803.2011.00595.x
M3 - Journal article
C2 - 22117860
VL - 6
SP - 566
EP - 572
JO - Congenital Heart Disease
JF - Congenital Heart Disease
SN - 1747-079X
IS - 6
ER -
ID: 242711730