Evaluating the dosimetric effect of intra-fractional variations in deep inspiration breath-hold radiotherapy - a proof-of-concept study
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Evaluating the dosimetric effect of intra-fractional variations in deep inspiration breath-hold radiotherapy - a proof-of-concept study. / Håkansson, K; Josipovic, M; Ottosson, W; Behrens, C P; Vogelius, I R; Persson, G.
In: Acta oncologica (Stockholm, Sweden), Vol. 62, No. 10, 2023, p. 1246-1250.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Evaluating the dosimetric effect of intra-fractional variations in deep inspiration breath-hold radiotherapy - a proof-of-concept study
AU - Håkansson, K
AU - Josipovic, M
AU - Ottosson, W
AU - Behrens, C P
AU - Vogelius, I R
AU - Persson, G
PY - 2023
Y1 - 2023
N2 - Deep inspiration breath-hold (DIBH) for radiotherapy (RT) can mitigate breathing motion [Citation1–3], improve cone-beam computed tomography (CBCT) image quality [Citation4] and create a favorable anatomy regarding dose to organs at risk (OARs) [Citation1,Citation5–8]. Initial concerns about patient compliance [Citation9] have been reconsidered, as both spirometry based and voluntary, optical tracking based DIBH technique are tolerated by most patients [Citation3,Citation7,Citation10,Citation11]. However, reproducibility and dosimetric benefit vary between patients, so a method for individual assessment is warranted. It is desirable to supplement geometrical/anatomical evaluation of the reproducibility with an estimate of the dosimetric effect of an observed variation in DIBH level.We provide a method to evaluate the dosimetric effect of intra-fractional variation in DIBH levels on a patient- and treatment plan specific level.
AB - Deep inspiration breath-hold (DIBH) for radiotherapy (RT) can mitigate breathing motion [Citation1–3], improve cone-beam computed tomography (CBCT) image quality [Citation4] and create a favorable anatomy regarding dose to organs at risk (OARs) [Citation1,Citation5–8]. Initial concerns about patient compliance [Citation9] have been reconsidered, as both spirometry based and voluntary, optical tracking based DIBH technique are tolerated by most patients [Citation3,Citation7,Citation10,Citation11]. However, reproducibility and dosimetric benefit vary between patients, so a method for individual assessment is warranted. It is desirable to supplement geometrical/anatomical evaluation of the reproducibility with an estimate of the dosimetric effect of an observed variation in DIBH level.We provide a method to evaluate the dosimetric effect of intra-fractional variation in DIBH levels on a patient- and treatment plan specific level.
KW - Humans
KW - Radiometry
KW - Radiotherapy Dosage
KW - Breath Holding
KW - Radiotherapy Planning, Computer-Assisted
KW - Heart
KW - Unilateral Breast Neoplasms
U2 - 10.1080/0284186X.2023.2259084
DO - 10.1080/0284186X.2023.2259084
M3 - Journal article
C2 - 37738385
VL - 62
SP - 1246
EP - 1250
JO - Acta Oncologica
JF - Acta Oncologica
SN - 1100-1704
IS - 10
ER -
ID: 387697277