European Ultrahigh-Field Imaging Network for Neurodegenerative Diseases (EUFIND)
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- D-zel_et_al-2019-Alzheimer's_&_Dementia__Diagnosis,_Assessment_&_Disease_Monitoring
Final published version, 2.35 MB, PDF document
Introduction: The goal of European Ultrahigh-Field Imaging Network in Neurodegenerative Diseases (EUFIND) is to identify opportunities and challenges of 7 Tesla (7T) MRI for clinical and research applications in neurodegeneration. EUFIND comprises 22 European and one US site, including over 50 MRI and dementia experts as well as neuroscientists.
Methods: EUFIND combined consensus workshops and data sharing for multisite analysis, focusing on 7 core topics: clinical applications/clinical research, highest resolution anatomy, functional imaging, vascular systems/vascular pathology, iron mapping and neuropathology detection, spectroscopy, and quality assurance. Across these topics, EUFIND considered standard operating procedures, safety, and multivendor harmonization.
Results: The clinical and research opportunities and challenges of 7T MRI in each subtopic are set out as a roadmap. Specific MRI sequences for each subtopic were implemented in a pilot study presented in this report. Results show that a large multisite 7T imaging network with highly advanced and harmonized imaging sequences is feasible and may enable future multicentre ultrahigh-field MRI studies and clinical trials.
Discussion: The EUFIND network can be a major driver for advancing clinical neuroimaging research using 7T and for identifying use-cases for clinical applications in neurodegeneration.
Original language | English |
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Journal | Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring |
Volume | 11 |
Issue number | 1 |
Pages (from-to) | 538-549 |
Number of pages | 12 |
ISSN | 2352-8729 |
DOIs | |
Publication status | Published - Dec 2019 |
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