Enhanced uptake and photoactivation of topical methyl aminolevulinate after fractional CO2 laser pretreatment
Research output: Contribution to journal › Journal article › Research › peer-review
Photodynamic therapy (PDT) of thick skin lesions is limited by topical drug uptake. Ablative fractional resurfacing (AFR) creates vertical channels that may facilitate topical PDT drug penetration and improve PDT-response in deep skin layers. The purpose of this study was to evaluate whether pre-treating the skin with AFR before topically applied methyl aminolevulinate (MAL) could enable a deep PDT-response.
Original language | English |
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Journal | Lasers in Surgery and Medicine |
Volume | 43 |
Issue number | 8 |
Pages (from-to) | 804-13 |
Number of pages | 10 |
ISSN | 0196-8092 |
DOIs | |
Publication status | Published - 2011 |
ID: 40161115