Employment status at time of first hospitalization for heart failure is associated with a higher risk of death and rehospitalization for heart failure
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Employment status at time of first hospitalization for heart failure is associated with a higher risk of death and rehospitalization for heart failure. / Rørth, Rasmus; Fosbøl, Emil L.; Mogensen, Ulrik M.; Kragholm, Kristian; Numé, Anna Karin; Gislason, Gunnar H.; Jhund, Pardeep S.; Petrie, Mark C.; McMurray, John J.V.; Torp-Pedersen, Christian; Køber, Lars; Kristensen, Søren L.
In: European Journal of Heart Failure, Vol. 20, No. 2, 2018, p. 240-247.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Employment status at time of first hospitalization for heart failure is associated with a higher risk of death and rehospitalization for heart failure
AU - Rørth, Rasmus
AU - Fosbøl, Emil L.
AU - Mogensen, Ulrik M.
AU - Kragholm, Kristian
AU - Numé, Anna Karin
AU - Gislason, Gunnar H.
AU - Jhund, Pardeep S.
AU - Petrie, Mark C.
AU - McMurray, John J.V.
AU - Torp-Pedersen, Christian
AU - Køber, Lars
AU - Kristensen, Søren L.
PY - 2018
Y1 - 2018
N2 - Aims: Employment status at time of first heart failure (HF) hospitalization may be an indicator of both self-perceived and objective health status. In this study, we examined the association between employment status and the risk of all-cause mortality and recurrent HF hospitalization in a nationwide cohort of patients with HF. Methods and results: We identified all patients of working age (18–60 years) with a first HF hospitalization in the period 1997–2015 in Denmark, categorized according to whether or not they were part of the workforce at time of the index admission. The primary outcome was death from any cause and the secondary outcome was readmission for HF. Cumulative incidence curves, binomial regression and Cox regression models were used to assess outcomes. Of 25 571 patients with a first hospitalization for HF, 15 428 (60%) were part of the workforce at baseline. Patients in the workforce were significantly younger (53 vs. 55 years) more likely to be male (75% vs 64%) and less likely to have diabetes (13% vs 22%) and chronic obstructive pulmonary disease (5% vs 10%) (all P < 0.0001). Not being part of the workforce was associated with a significantly higher risk of death [hazard ratio (HR) 1.59; 95% confidence interval (CI) 1.50–1.68] and rehospitalization for HF (HR 1.09; 95% CI 1.05–1.14), in analyses adjusted for age, sex, co-morbidities, education level, calendar time, and duration of first HF hospitalization. Conclusion: Not being part of the workforce at time of first HF hospitalization was independently associated with increased mortality and recurrent HF hospitalization.
AB - Aims: Employment status at time of first heart failure (HF) hospitalization may be an indicator of both self-perceived and objective health status. In this study, we examined the association between employment status and the risk of all-cause mortality and recurrent HF hospitalization in a nationwide cohort of patients with HF. Methods and results: We identified all patients of working age (18–60 years) with a first HF hospitalization in the period 1997–2015 in Denmark, categorized according to whether or not they were part of the workforce at time of the index admission. The primary outcome was death from any cause and the secondary outcome was readmission for HF. Cumulative incidence curves, binomial regression and Cox regression models were used to assess outcomes. Of 25 571 patients with a first hospitalization for HF, 15 428 (60%) were part of the workforce at baseline. Patients in the workforce were significantly younger (53 vs. 55 years) more likely to be male (75% vs 64%) and less likely to have diabetes (13% vs 22%) and chronic obstructive pulmonary disease (5% vs 10%) (all P < 0.0001). Not being part of the workforce was associated with a significantly higher risk of death [hazard ratio (HR) 1.59; 95% confidence interval (CI) 1.50–1.68] and rehospitalization for HF (HR 1.09; 95% CI 1.05–1.14), in analyses adjusted for age, sex, co-morbidities, education level, calendar time, and duration of first HF hospitalization. Conclusion: Not being part of the workforce at time of first HF hospitalization was independently associated with increased mortality and recurrent HF hospitalization.
KW - Employment status
KW - Epidemiology
KW - Heart failure
U2 - 10.1002/ejhf.1046
DO - 10.1002/ejhf.1046
M3 - Journal article
C2 - 29148231
AN - SCOPUS:85034212846
VL - 20
SP - 240
EP - 247
JO - European Journal of Heart Failure
JF - European Journal of Heart Failure
SN - 1567-4215
IS - 2
ER -
ID: 214403135