Effects of F/G-actin ratio and actin turn-over rate on NADPH oxidase activity in microglia
Research output: Contribution to journal › Journal article › Research › peer-review
Most in vivo studies that have addressed the role of actin dynamics in NADPH oxidase function in phagocytes have used toxins to modulate the polymerization state of actin and mostly effects on actin has been evaluated by end point measurements of filamentous actin, which says little about actin dynamics, and without consideration for the subcellular distribution of the perturbed actin cytoskeleton.
| Original language | English |
|---|---|
| Journal | B M C Immunology |
| Volume | 11 |
| Pages (from-to) | 44 |
| ISSN | 1471-2172 |
| DOIs | |
| Publication status | Published - 1 Sep 2010 |
- Actin Depolymerizing Factors, Actins, Animals, Cell Line, Cloning, Molecular, Cytoskeleton, Enzyme Activation, Humans, Lim Kinases, Mice, Microglia, N-Formylmethionine Leucyl-Phenylalanine, NADPH Oxidase, Polymerization, RNA, Small Interfering, Transgenes
Research areas
ID: 33750982