Differential outcomes of open and clamp-on distal anastomosis techniques in acute type A aortic dissection
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Differential outcomes of open and clamp-on distal anastomosis techniques in acute type A aortic dissection. / Geirsson, Arnar; Shioda, Kayoko; Olsson, Christian; Ahlsson, Anders; Gunn, Jarmo; Hansson, Emma C; Hjortdal, Vibeke; Jeppsson, Anders; Mennander, Ari; Wickbom, Anders; Zindovic, Igor; Gudbjartsson, Tomas.
In: The Journal of Thoracic and Cardiovascular Surgery, Vol. 157, No. 5, 05.2019, p. 1750-1758.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Differential outcomes of open and clamp-on distal anastomosis techniques in acute type A aortic dissection
AU - Geirsson, Arnar
AU - Shioda, Kayoko
AU - Olsson, Christian
AU - Ahlsson, Anders
AU - Gunn, Jarmo
AU - Hansson, Emma C
AU - Hjortdal, Vibeke
AU - Jeppsson, Anders
AU - Mennander, Ari
AU - Wickbom, Anders
AU - Zindovic, Igor
AU - Gudbjartsson, Tomas
N1 - Published by Elsevier Inc.
PY - 2019/5
Y1 - 2019/5
N2 - OBJECTIVES: Open-distal anastomosis is the preferred technique over clamp-on technique for surgical repair of acute type A aortic dissection (ATAAD). The aim of this study was to define how outcomes of ATAAD were affected by the use of either technique.METHODS: Nordic Consortium for Acute Type A Aortic Dissection includes 8 academic cardiothoracic hospitals in 4 Nordic countries. The cohort consisted of 1134 patients, 153 clamp-on and 981 open-distal, from 2005 to 2014.RESULTS: Patients who underwent operation with the clamp-on were younger, more frequently had coronary artery disease, bicuspid aortic valve, hypotension/shock or syncope, and a greater PennClass than open-distal patients. Postoperative cerebral vascular accident occurred less frequently in clamp-on (14/153, 10%) compared with the open-distal group (190/981, 20%). Clamp-on had greater 30-day mortality (39/153, 25%) than the open-distal group (158/981, 16%), and 5-year survival was also worse in clamp-on (61.8% ± 4.4%) compared with the open-distal group (73.0% ± 1.6%). The open-distal technique was used more frequently in greater-volume hospitals but was not independently associated with 30-day mortality. Preoperative condition was an independent risk factor whereas hospital volume and later year of operation were beneficial in regard to short-term outcome. Open-distal was independently associated with improved mid-term survival.CONCLUSIONS: Patients who underwent operation with the clamp-on were sicker on presentation and had worse short- and mid-term survival compared with the open-distal group. Patients in the open-distal group had greater rates of cerebrovascular complications. The results support the routine use of open-distal anastomosis as the primary operative strategy for ATAAD, although clamp-on can be performed successfully in select cases.
AB - OBJECTIVES: Open-distal anastomosis is the preferred technique over clamp-on technique for surgical repair of acute type A aortic dissection (ATAAD). The aim of this study was to define how outcomes of ATAAD were affected by the use of either technique.METHODS: Nordic Consortium for Acute Type A Aortic Dissection includes 8 academic cardiothoracic hospitals in 4 Nordic countries. The cohort consisted of 1134 patients, 153 clamp-on and 981 open-distal, from 2005 to 2014.RESULTS: Patients who underwent operation with the clamp-on were younger, more frequently had coronary artery disease, bicuspid aortic valve, hypotension/shock or syncope, and a greater PennClass than open-distal patients. Postoperative cerebral vascular accident occurred less frequently in clamp-on (14/153, 10%) compared with the open-distal group (190/981, 20%). Clamp-on had greater 30-day mortality (39/153, 25%) than the open-distal group (158/981, 16%), and 5-year survival was also worse in clamp-on (61.8% ± 4.4%) compared with the open-distal group (73.0% ± 1.6%). The open-distal technique was used more frequently in greater-volume hospitals but was not independently associated with 30-day mortality. Preoperative condition was an independent risk factor whereas hospital volume and later year of operation were beneficial in regard to short-term outcome. Open-distal was independently associated with improved mid-term survival.CONCLUSIONS: Patients who underwent operation with the clamp-on were sicker on presentation and had worse short- and mid-term survival compared with the open-distal group. Patients in the open-distal group had greater rates of cerebrovascular complications. The results support the routine use of open-distal anastomosis as the primary operative strategy for ATAAD, although clamp-on can be performed successfully in select cases.
KW - Acute Disease
KW - Adult
KW - Age Factors
KW - Aged
KW - Anastomosis, Surgical
KW - Aortic Aneurysm/diagnostic imaging
KW - Comorbidity
KW - Constriction
KW - Female
KW - Humans
KW - Male
KW - Middle Aged
KW - Postoperative Complications/mortality
KW - Retrospective Studies
KW - Risk Assessment
KW - Risk Factors
KW - Scandinavian and Nordic Countries/epidemiology
KW - Time Factors
KW - Treatment Outcome
KW - Vascular Surgical Procedures/adverse effects
U2 - 10.1016/j.jtcvs.2018.09.020
DO - 10.1016/j.jtcvs.2018.09.020
M3 - Journal article
C2 - 30401530
VL - 157
SP - 1750
EP - 1758
JO - Journal of Thoracic and Cardiovascular Surgery
JF - Journal of Thoracic and Cardiovascular Surgery
SN - 0022-5223
IS - 5
ER -
ID: 246199472